The Global Protocatechuic Acid (CAS 99-50-3) Market was valued at USD 12.3 Million in
2024 and is projected to grow from USD 12.8 Million in 2025 to reach USD
16 Million by 2032, exhibiting a Compound Annual Growth Rate (CAGR) of 3.9% during
the forecast period. This growth is driven by increasing demand for natural antioxidants in pharmaceutical
formulations, the expanding nutraceutical industry, and rising research into the compound’s therapeutic potential
for chronic diseases.

As the healthcare and chemical industries increasingly prioritize natural and bioactive ingredients, the spotlight
is on the key manufacturers who are driving innovation, production efficiency, and quality control. In this blog,
we profile the Top 10 Companies in the Protocatechuic Acid Industry—a mix of established Chinese
producers, specialized chemical suppliers, and emerging players shaping the global supply chain for this
versatile phenolic acid.

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🔟 1. Taizhou Zhongda Chemical Co., Ltd.

Headquarters: Taizhou, Jiangsu, China
Key Offering: Pharmaceutical Grade PCA, Industrial Grade PCA, Custom Synthesis

Taizhou Zhongda Chemical is a leading producer of Protocatechuic Acid, controlling approximately 15% of the
global production capacity. The company leverages its integrated manufacturing facilities in China’s
pharmaceutical hub to offer high-purity PCA for diverse applications, from drug intermediates to food
antioxidants.

Innovation Initiatives:

• Investment in advanced purification technologies for >99% purity grades

• Strategic partnerships with international nutraceutical brands

• Focus on scaling up production to meet rising global demand

Download FREE Sample Report:
Protocatechuic Acid (CAS 99-50-3) Market – View in Detailed Research Report

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9️⃣ 2. Henan Lyle Wormwood Industrial Co., Ltd.

Headquarters: Zhengzhou, Henan, China
Key Offering: Plant-Extracted PCA, Botanical Extracts, Natural Antioxidants

Henan Lyle Wormwood specializes in plant-derived Protocatechuic Acid, utilizing sustainable extraction
methodologies from wormwood and other botanical sources. The company has established a strong presence in the
natural products market, supplying ingredients for health supplements and functional foods.

Innovation Initiatives:

• Development of proprietary extraction techniques for higher yields

• Emphasis on organic and non-GMO sourcing of raw materials

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8️⃣ 3. Aktin Chemicals, Inc.

Headquarters: Xi’an, Shaanxi, China
Key Offering: High-Purity PCA, Research Chemicals, Custom Manufacturing

Aktin Chemicals is a respected supplier focusing on high-quality Protocatechuic Acid for research and development
purposes. The company caters to pharmaceutical companies and academic institutions requiring precise
specifications for clinical studies and formulation development.

Innovation Initiatives:

• Supply of PCA metabolites and derivatives for advanced research

• Collaboration with universities on bioavailability enhancement studies

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7️⃣ 4. Xi’an Season Biotechnology Co., Ltd.

Headquarters: Xi’an, Shaanxi, China
Key Offering: PCA Extracts, Herbal Active Ingredients, Nutraceutical Raw Materials

Xi’an Season Biotechnology is a key player in the botanical extract industry, producing Protocatechuic Acid from
green tea and other phenolic-rich plants. The company’s expertise lies in standardizing active compounds for
consistent quality in end products.

Innovation Initiatives:

• Implementation of rigorous quality control protocols for international standards

• Expansion into cosmeceutical applications for PCA

Download FREE Sample Report:
Protocatechuic Acid (CAS 99-50-3) Market – View in Detailed Research Report

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6️⃣ 5. Hangzhou Hyper Chemicals Limited

Headquarters: Hangzhou, Zhejiang, China
Key Offering: Synthetic PCA, Chemical Intermediates, Bulk Pharma Ingredients

Hangzhou Hyper Chemicals focuses on the chemical synthesis of Protocatechuic Acid, offering cost-effective
solutions for large-volume industrial and pharmaceutical customers. The company’s strength lies in its scalable
production processes and competitive pricing.

Innovation Initiatives:

• Optimization of synthesis routes to reduce production costs

• Development of stable PCA formulations for enhanced shelf life

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5️⃣ 6. Kingherbs Limited

Headquarters: Xi’an, Shaanxi, China
Key Offering: Organic PCA, Standardized Extracts, GMP-certified Ingredients

Kingherbs Limited has built a reputation for supplying high-quality, GMP-certified Protocatechuic Acid derived
from organic sources. The company serves premium segments of the nutraceutical and functional food markets,
particularly in North America and Europe.

Innovation Initiatives:

• Certification for organic and non-GMO product lines

• Investment in green chemistry principles for sustainable production

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4️⃣ 7. Shaanxi Huike Botanical Development Co., Ltd.

Headquarters: Xi’an, Shaanxi, China
Key Offering: Botanical PCA, Plant-Based Actives, Traditional Medicine Ingredients

Shaanxi Huike Botanical Development specializes in extracting Protocatechuic Acid from traditional medicinal
plants. The company combines modern extraction technologies with knowledge of herbal medicine to produce PCA
with specific phytochemical profiles.

Innovation Initiatives:

• Research on synergistic effects of PCA with other plant compounds

• Development of standardized extracts for traditional medicine applications

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3️⃣ 8. Hunan NutraMax Inc.

Headquarters: Changsha, Hunan, China
Key Offering: Nutraceutical-Grade PCA, Dietary Supplement Ingredients, Functional Food
Additives

Hunan NutraMax focuses on the nutraceutical applications of Protocatechuic Acid, developing formulations tailored
for dietary supplements and health foods. The company works closely with brand owners to customize PCA solutions
for specific health claims.

Innovation Initiatives:

• Formulation support for PCA-based supplement products

• Stability testing for various delivery formats (capsules, powders, liquids)

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2️⃣ 9. Jiangsu Panson Extraction Technology Co.

Headquarters: Nantong, Jiangsu, China
Key Offering: Advanced PCA Extracts, Extraction Technology Services, Custom Isolation

Jiangsu Panson Extraction Technology distinguishes itself through advanced extraction methodologies, including
supercritical CO2 and microwave-assisted extraction for Protocatechuic Acid. The company serves as both a
manufacturer and a technology provider to the industry.

Innovation Initiatives:

• Licensing of proprietary extraction technologies to other manufacturers

• Development of solvent-free extraction processes for premium markets

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1️⃣ 10. Other Emerging Players

Headquarters: Various global locations
Key Offering: Niche PCA applications, Regional specialties, Innovation-focused solutions

Beyond the established leaders, several emerging companies are making significant contributions to the
Protocatechuic Acid market. These include specialized chemical suppliers in India, botanical extractors in
Southeast Asia, and biotechnology startups in Western markets focusing on novel applications and production
methods.

Innovation Initiatives:

• Development of PCA for specialized therapeutic areas

• Exploration of microbial fermentation for sustainable PCA production

Get Full Report Here:
Protocatechuic Acid (CAS 99-50-3) Market – View in Detailed Research Report

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🌍 Outlook: The Future of Protocatechuic Acid Is Diversified and Innovative

The Protocatechuic Acid market is undergoing a significant transformation. While traditional pharmaceutical
applications continue to dominate, the industry is investing in novel extraction technologies,
application development, and sustainability initiatives.

📈 Key Trends Shaping the Market:

• Expansion into cosmeceuticals and advanced drug delivery systems

• Growing consumer preference for plant-derived bioactive compounds

• Increasing research validating PCA’s therapeutic potential in chronic diseases

• Technological advancements improving production efficiency and purity levels

Get Full Report Here:
Protocatechuic Acid (CAS 99-50-3) Market – View in Detailed Research Report

The companies listed above are not only supplying a critical bioactive compound—they’re driving
the innovation ecosystem for natural products in healthcare and wellness.