The Global Sodium Hyaluronate Market was valued at USD 520 Million in 2025 and is projected to reach USD 1,117 Million by 2032, growing at a Compound Annual Growth Rate (CAGR) of 14.1% during the forecast period (2025–2032). This impressive growth is being driven by escalating demand in anti-aging skincare, expanding applications in pharmaceutical treatments, and the recent regulatory approval for use in functional foods, particularly in key markets like China.

As the global beauty and wellness industries continue their upward trajectory, the focus intensifies on the key ingredient manufacturers who are pioneering advanced formulations and sustainable production methods. In this blog, we profile the Top 10 Companies in the Sodium Hyaluronate Industry—a diverse group of biotechnology firms, pharmaceutical giants, and specialty chemical producers shaping the future of this dynamic market.

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🔟 1. Bloomage Biotech

Headquarters: Jinan, Shandong, China
Key Offering: Pharmaceutical-grade, Cosmetic-grade, and Food-grade Sodium Hyaluronate

Bloomage Biotech is the undisputed global leader in the sodium hyaluronate market, commanding a significant revenue share. The company operates as a fully integrated manufacturer, controlling the entire production process from microbial fermentation to final product formulation. Its diverse portfolio serves the cosmetic, pharmaceutical, and nutraceutical industries worldwide.

Innovation Initiatives:

• Pioneering ultra-low molecular weight HA for enhanced skin penetration
• Major investments in fermentation technology to increase yield and purity
• Strategic partnerships with global cosmetic and pharmaceutical brands

Download FREE Sample Report: Sodium Hyaluronate Market – View in Detailed Research Report

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9️⃣ 2. Fidia Farmaceutici

Headquarters: Abano Terme, Italy
Key Offering: High-purity Medical-grade Sodium Hyaluronate, Orthopedic and Ophthalmic Products

Fidia Farmaceutici is a world-renowned specialist in hyaluronic acid-based medical devices and pharmaceuticals. With decades of expertise, the company is a key player in viscosupplementation for osteoarthritis and products for ophthalmic surgery. Its stringent quality control and extensive clinical data make it a trusted partner in the healthcare sector.

Innovation Initiatives:

• Leading research in cross-linked hyaluronic acid for long-lasting joint treatments
• Development of novel formulations for wound healing and scar management

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8️⃣ 3. Kewpie Corporation

Headquarters: Tokyo, Japan
Key Offering: High Molecular Weight Sodium Hyaluronate, Q’tyl® (Hydrolyzed Hyaluronic Acid)

Kewpie Corporation, a leading Japanese food and cosmetic ingredient company, has established a strong position in the sodium hyaluronate market. Leveraging its expertise in bioscience, Kewpie produces high-quality HA through proprietary microbial fermentation processes and offers specialized low-molecular-weight variants for superior skin absorption.

Innovation Initiatives:

• Focus on sustainable, bio-fermented production methods
• Expansion into oral hyaluronic acid supplements for beauty-from-within trends

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7️⃣ 4. Seikagaku Corporation

Headquarters: Tokyo, Japan
Key Offering: Pharmaceutical-grade Sodium Hyaluronate, ARTZ® for osteoarthritis

Seikagaku Corporation is a prominent Japanese pharmaceutical company with a longstanding focus on glycoscience, including hyaluronic acid. It is a major supplier of high-purity sodium hyaluronate for intra-articular injections and ophthalmic viscosurgical devices, backed by robust research and development.

Innovation Initiatives:

• Continuous improvement of purification processes for ultra-pure medical-grade HA
• Research into new therapeutic applications for hyaluronic acid in regenerative medicine

Download FREE Sample Report: Sodium Hyaluronate Market – View in Detailed Research Report

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6️⃣ 5. Contipro

Headquarters: Dolní Dobrouč, Czech Republic
Key Offering: Hyaluronic Acid of various molecular weights, Dermal Fillers

Contipro is a leading European biotechnology company specializing in the research, development, and production of hyaluronic acid and its derivatives. It is recognized for its innovative approach, producing a wide range of HA molecular weights tailored for specific cosmetic and medical applications, including its own line of dermal fillers.

Innovation Initiatives:

• Development of proprietary stabilized HA forms (e.g., OxiFree®)
• Strong focus on R&D for advanced drug delivery systems using HA

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5️⃣ 6. HTL Biotechnology

Headquarters: Javené, France
Key Offering: HYAJE® (Hyaluronic Acid) ingredients, Custom Hyaluronic Acid solutions

HTL Biotechnology is a key European manufacturer of fermented hyaluronic acid. The company supplies high-quality ingredients to the cosmetic, nutraceutical, and pharmaceutical industries, with a reputation for technical expertise and the ability to create customized HA solutions for specific customer formulations.

Innovation Initiatives:

• Investment in eco-friendly fermentation processes
• Expansion of product portfolio to include new derivatives and complexes

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4️⃣ 7. Givaudan Active Beauty

Headquarters: Vernier, Switzerland
Key Offering: Hyaluronic Acid-based active ingredients, Finished formulations

While not a primary producer of raw sodium hyaluronate, Givaudan Active Beauty is a crucial player in the value chain, incorporating HA into sophisticated active ingredients and finished formulations for the global cosmetics industry. Its market influence lies in its ability to drive demand through innovative product development and strong client relationships.

Innovation Initiatives:

• Development of multi-functional complexes featuring hyaluronic acid
• Focus on sustainable sourcing and green chemistry principles

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3️⃣ 8. Fufeng Group

Headquarters: Shandong, China
Key Offering: Bulk Sodium Hyaluronate, Fermentation-based Bio-products

Fufeng Group is a major Chinese bio-fermentation company that produces a wide array of products, including sodium hyaluronate. Leveraging its large-scale fermentation capabilities and cost advantages, Fufeng is a significant supplier of bulk HA, particularly for the cosmetic and food industries.

Innovation Initiatives:

• Scaling up production capacity to meet growing global demand
• Optimizing fermentation strains for higher yield and efficiency

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2️⃣ 9. China Eastar Group

Headquarters: Dongying, Shandong, China
Key Offering: Cosmetic and Food grade Sodium Hyaluronate

China Eastar Group is another key Chinese manufacturer contributing significantly to the global supply of sodium hyaluronate. The company focuses on producing quality HA for the expanding cosmetic and, more recently, the food and beverage markets following regulatory changes in China.

Innovation Initiatives:

• Expansion into value-added HA derivatives
• Certification and compliance efforts for international market access

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1️⃣ 10. Kikkoman Corporation

Headquarters: Noda, Chiba, Japan
Key Offering: Hyaluronic Acid for food and cosmetics

Known globally for its soy sauce, Kikkoman Corporation also has a biotechnology division that produces hyaluronic acid. Utilizing its expertise in fermentation, Kikkoman produces high-quality HA, with a particular focus on applications in functional foods and cosmetics, capitalizing on the “beauty from within” trend.

Innovation Initiatives:

• Leveraging food-grade fermentation expertise for HA production
• Promoting the use of HA in nutraceuticals and health foods

Get Full Report Here: Sodium Hyaluronate Market – View in Detailed Research Report

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🧴 Outlook: The Future of Sodium Hyaluronate Is Personalized and Sustainable

The sodium hyaluronate market is experiencing a paradigm shift. While traditional skincare applications continue to dominate, the industry is heavily investing in medical-grade innovations, sustainable production technologies, and new applications in nutraceuticals.

📈 Key Trends Shaping the Market:

• Rising demand for high-purity, pharmaceutical-grade HA in orthopedics and ophthalmology
• Expansion of the “edible beauty” segment with HA-infused functional foods and supplements
• Advancements in fermentation technology for cost-effective and eco-friendly production
• Growing consumer preference for scientifically-backed, “clean” beauty ingredients

Get Full Report Here: Sodium Hyaluronate Market – View in Detailed Research Report

The companies listed above are not only supplying a key global ingredient—they’re pioneering the science of hydration and regeneration across multiple industries.