The Global Liquiritigenin Market was valued at US$ 25.8 Million in 2023 and is projected to reach US$ 39.5 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 6.3% during the forecast period (2024–2030). This growth is being driven by the rising demand for natural therapeutics, increasing research into flavonoid-based medicines, and the expanding application of liquiritigenin in pharmaceuticals, nutraceuticals, and functional foods.

As the health and wellness sector increasingly turns to plant-derived bioactive compounds, the focus intensifies on the key manufacturers and suppliers ensuring the quality, purity, and availability of liquiritigenin. In this blog, we profile the Top 10 Companies in the Liquiritigenin Industry—a blend of established life science reagent suppliers, biotechnology firms, and specialized chemical producers shaping the future of this niche but vital market.

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🔟 1. Tocris Bioscience (A Bio-Techne Brand)

Headquarters: Bristol, United Kingdom
Key Offering: High-Purity Liquiritigenin (≥98% by HPLC), Research Grade

Tocris Bioscience, a renowned Bio-Techne brand, is a leading global supplier of high-quality performance biochemicals for life science research. Their liquiritigenin is widely used in academic and pharmaceutical R&D for studying estrogen receptor beta (ERβ) activity and other pharmacological pathways.

Research & Development Initiatives:

• Provision of high-purity, well-characterized reference standards
• Support for preclinical research in oncology, neurology, and inflammation
• Integration into comprehensive pharmacological toolkits for scientists

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9️⃣ 2. ChemFaces

Headquarters: Wuhan, Hubei, China
Key Offering: Liquiritigenin (98%-99% Purity), Natural Product Extracts

ChemFaces specializes in the isolation and synthesis of high-purity natural products and reference standards. The company serves the global research community with a reliable supply of liquiritigenin, sourced and purified to meet stringent quality requirements for analytical and biological testing.

Research & Development Initiatives:

• Extensive catalog of flavonoid and isoflavonoid compounds
• Custom purification and synthesis services for research institutions
• Focus on scalability for transitioning from research to potential commercial applications

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8️⃣ 3. Merck KGaA

Headquarters: Darmstadt, Germany
Key Offering: Liquiritigenin (Analytical Standard), Life Science Reagents

Merck, a global leader in science and technology, offers liquiritigenin as part of its extensive portfolio of life science reagents and analytical standards. The company’s products are critical for drug discovery, quality control, and academic research worldwide, ensuring reproducibility and compliance.

Research & Development Initiatives:

• Distribution of certified reference materials for accurate analytical results
• Investment in sustainable sourcing and production of natural products
• Support for global pharmaceutical and academic research collaborations

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7️⃣ 4. Santa Cruz Biotechnology, Inc.

Headquarters: Dallas, Texas, USA
Key Offering: Liquiritigenin (for research use), Antibodies, Biochemicals

Santa Cruz Biotechnology is a major supplier of research reagents, including a diverse range of small molecules like liquiritigenin. The company supports investigative biology with products designed for studying cell signaling, gene expression, and metabolic pathways.

Research & Development Initiatives:

• Provision of reagents for cancer, metabolic, and neurological disease research
• Development of companion research tools, such as antibodies for related targets
• Commitment to supplying the global biomedical research community

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6️⃣ 5. Cayman Chemical Company

Headquarters: Ann Arbor, Michigan, USA
Key Offering: High-Purity Liquiritigenin, Screening Libraries, Bioactive Lipids

Cayman Chemical is a leading supplier of biochemicals for research, including a comprehensive portfolio of natural products. Their high-purity liquiritigenin is utilized in drug discovery programs focused on its anti-inflammatory, neuroprotective, and phytoestrogen properties.

Research & Development Initiatives:

• Specialization in assay-ready chemicals and screening compounds
• Integration into targeted libraries for high-throughput screening (HTS)
• Focus on quality control for reproducible pharmacological data

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5️⃣ 6. TargetMol Chemicals Inc.

Headquarters: Boston, Massachusetts, USA
Key Offering: Liquiritigenin (for Inhibitor Screening), Natural Product Libraries

TargetMol provides a vast collection of bioactive small molecules, including liquiritigenin, for drug discovery and development. The company is known for its expertly curated compound libraries that help researchers identify novel therapeutic agents efficiently.

Research & Development Initiatives:

• Classification of liquiritigenin within natural product and inhibitor libraries
• Provision of detailed pharmacological data and structure-activity relationships (SAR)
• Support for virtual screening and cheminformatics applications

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4️⃣ 7. BOC Sciences

Headquarters: Shirley, New York, USA
Key Offering: Liquiritigenin (Custom Purity Grades), API Sourcing

BOC Sciences offers a wide array of chemical products and services, from research chemicals to potential Active Pharmaceutical Ingredient (API) sourcing. Their liquiritigenin supply caters to both early-stage research and later-stage development needs.

Research & Development Initiatives:

• Custom synthesis and scale-up services for development candidates
• GMP-compliant services for advancing natural products towards clinical trials
• Strong sourcing network for plant-derived compounds

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3️⃣ 8. Selleck Chemicals

Headquarters: Houston, Texas, USA
Key Offering: Liquiritigenin (High-Grade), Targeted Cancer Therapy Compounds

Selleck Chemicals is a global supplier of novel inhibitors for cancer research and other therapeutic areas. The company lists liquiritigenin among its natural product offerings, highlighting its potential application in oncology and inflammation research.

Research & Development Initiatives:

• Focus on providing inhibitors for well-defined biological targets
• Contribution to preclinical research in hormone-related cancers and metabolic diseases
• Emphasis on batch-to-batch consistency for research integrity

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2️⃣ 9. AdooQ BioScience

Headquarters: Irvine, California, USA
Key Offering: Liquiritigenin (Bioassay Grade), Cell Signaling Inhibitors

AdooQ BioScience specializes in small molecule inhibitors and agonists for research use. Their liquiritigenin product is marketed for its role as a selective ERβ agonist, supporting research into endocrine-disrupting chemicals, women’s health, and more.

Research & Development Initiatives:

• Development of compound-based research kits for specific pathways
• Supply of bioassay-ready compounds with verified activity data
• Support for academic and pharmaceutical discovery programs

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1️⃣ 10. Sigma-Aldrich (Merck Group)

Headquarters: St. Louis, Missouri, USA
Key Offering: Liquiritigenin (Analytical Standard, ≥98%), Laboratory Reagents

As part of the Merck Group, Sigma-Aldrich is one of the world’s largest suppliers of laboratory chemicals and biochemicals. The company provides liquiritigenin as a high-purity standard essential for analytical chemistry, quality control labs, and biological research.

Research & Development Initiatives:

• Global distribution network ensuring reliable supply for researchers
• Rigorous quality control and certification for analytical standards
• Integration into a vast ecosystem of research tools and technologies

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Liquiritigenin Market – View in Detailed Research Report

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🌍 Outlook: The Future of Liquiritigenin Is Rooted in Science and Sustainability

The liquiritigenin market is experiencing a significant transformation. While its primary use remains in research, growing evidence of its health benefits is paving the way for broader applications in nutraceuticals and pharmaceuticals.

📈 Key Trends Shaping the Market:

• Increasing R&D investment into natural products for chronic disease management
• Rising consumer preference for plant-based and natural therapeutic agents
• Advancements in extraction and purification technologies enhancing yield and purity
• Strategic collaborations between academic institutions and ingredient suppliers for clinical validation

The companies listed above are not only supplying a critical research chemical—they are enabling the scientific exploration that could unlock its full therapeutic potential for global health.

Get Full Report Here:
Liquiritigenin Market – View in Detailed Research Report