Top 10 Companies in the Olive Squalene Market: Leaders Driving Sustainable Skincare and Pharmaceutical Innovation

In Business Insights
January 08, 2026



The Global Olive Squalene Market was valued at USD 140.3 Million in 2024 and is projected to reach USD 220.8 Million by 2032, growing at a Compound Annual Growth Rate (CAGR) of 5.8% during the forecast period (2024–2032). This growth is being driven by rising consumer demand for natural and sustainable cosmetic ingredients, expanding pharmaceutical applications, and the shift away from shark-derived squalene due to environmental concerns.

As the cosmetics and pharmaceutical industries increasingly prioritize plant-based, biocompatible ingredients, olive squalene has emerged as a premium alternative. This natural emollient, derived from olive oil, offers superior moisturizing and antioxidant properties. In this blog, we profile the Top 10 Companies in the Olive Squalene Industry—a mix of biotechnology pioneers, specialty chemical producers, and ingredient suppliers shaping the future of this high-growth market.


🔟 1. Amyris, Inc.

Headquarters: Emeryville, California, USA
Key Offering: Biofene® (Farnesene-derived Squalene), High-Purity Pharmaceutical Grade

Amyris is a leading biotechnology company that produces squalene through its proprietary fermentation technology, offering a sustainable and scalable alternative to traditional sources. Their Biofene® brand is a key ingredient in high-end cosmetics and vaccine adjuvants.

Sustainability Initiatives:

  • 100% plant-based, renewable production process

  • Strategic partnerships with major cosmetic and vaccine manufacturers

  • Commitment to reducing environmental impact through synthetic biology

Download FREE Sample Report: https://www.24chemicalresearch.com/download-sample/263015/olive-squalene-market


9️⃣ 2. Clariant AG

Headquarters: Muttenz, Switzerland
Key Offering: Vegapure® Squalene, Cosmetic and Pharmaceutical Grades

Clariant is a global specialty chemicals leader, offering high-purity olive-derived squalene under its Vegapure® brand. The company focuses on natural, high-performance ingredients for the personal care and healthcare industries.

Sustainability Initiatives:

  • Investment in green chemistry and sustainable sourcing

  • Development of eco-friendly extraction and purification processes


8️⃣ 3. EFP Biotek

Headquarters: Barcelona, Spain
Key Offering: Olive Squalene, Squalane, and custom lipid formulations

EFP Biotek specializes in the production of high-quality lipids from vegetable sources, with a strong focus on olive squalene. The company serves the pharmaceutical, nutraceutical, and cosmetic sectors with certified organic and conventional products.

Sustainability Initiatives:

  • Vertically integrated supply chain from Spanish olive groves

  • Certified organic production and full traceability


7️⃣ 4. Green Oleo

Headquarters: Grasse, France
Key Offering: Olive Squalene OLEÏSQUAL®, Squalane

Green Oleo is a French company dedicated to producing natural ingredients from olive oil by-products. Their OLEÏSQUAL® range is known for its high purity and is used in luxury skincare and pharmaceutical formulations.

Sustainability Initiatives:

  • Utilization of olive pomace, a by-product of olive oil production

  • Commitment to a circular economy model

Download FREE Sample Report: https://www.24chemicalresearch.com/download-sample/263015/olive-squalene-market


6️⃣ 5. Botani Pty Ltd

Headquarters: Melbourne, Australia
Key Offering: Botani Olive Squalene, 100% Pure Organic

Botani is an Australian natural skincare brand and ingredient supplier that produces 100% pure olive squalene. Their product is renowned for its organic certification and effectiveness in sensitive skin formulations.

Sustainability Initiatives:

  • Focus on organic and ethically sourced ingredients

  • Development of cruelty-free and vegan-certified products


5️⃣ 6. Krishana Enterprises

Headquarters: Mumbai, India
Key Offering: Olive Squalene, Pharmaceutical and Cosmetic Grades

Krishana Enterprises is a key supplier of natural oils and lipids in the Asian market, offering competitively priced olive squalene. The company caters to a growing domestic and international demand for plant-based ingredients.

Sustainability Initiatives:

  • Sourcing from sustainable olive farms

  • Investment in green extraction technologies


4️⃣ 7. OLEICFAT, S.L.

Headquarters: Seville, Spain
Key Offering: Olive-derived Squalene, Refined Olive Oil Fractions

Based in the heart of Spain’s olive oil region, OLEICFAT specializes in extracting high-value compounds like squalene from olive oil. The company leverages its proximity to raw materials to ensure supply chain efficiency.

Sustainability Initiatives:

  • Local sourcing reducing carbon footprint

  • Zero-waste production philosophy


3️⃣ 8. Nucelis LLC

Headquarters: San Diego, California, USA
Key Offering: Fermentation-derived Squalene, Sustainable Alternatives

Nucelis is a biotechnology firm using advanced fermentation to produce sustainable ingredients, including squalene. Their innovative approach provides a consistent and scalable supply independent of agricultural variables.

Sustainability Initiatives:

  • Development of non-GMO microbial fermentation processes

  • Focus on creating a secure, non-commodity-based supply chain


2️⃣ 9. SeaDragon Marine Oils Ltd

Headquarters: Nelson, New Zealand
Key Offering: Olive Squalene, Shark Squalene, Omega-3 Oils

SeaDragon, traditionally known for marine oils, has expanded into plant-based squalene to meet the demand for sustainable alternatives. They offer both olive-derived and shark-derived options, catering to diverse market needs.

Sustainability Initiatives:

  • Transitioning product portfolio towards plant-based sources

  • Investment in refining technologies for olive squalene


1️⃣ 10. Sophim

Headquarters: Peyruis, France
Key Offering: Phytosqualan®, Olive-derived Squalane

Sophim is a leading European producer of squalane derived from olive oil. Their flagship product, Phytosqualan®, is a hydrogenated form of squalene known for its exceptional stability and skin compatibility in cosmetic formulations.

Sustainability Initiatives:

  • Ethical sourcing from European olive growers

  • Eco-friendly manufacturing processes with low energy consumption

Get Full Report Here: https://www.24chemicalresearch.com/reports/263015/olive-squalene-market


🌿 Outlook: The Future of Olive Squalene is Natural and High-Performance

The olive squalene market is undergoing a significant transformation. While traditional shark-derived squalene is still used, the industry is rapidly shifting towards plant-based alternatives driven by sustainability demands and superior consumer perception.

📈 Key Trends Shaping the Market:

  • Rising demand for clean-label and natural ingredients in cosmetics

  • Expansion of pharmaceutical applications, particularly in vaccine adjuvants and drug delivery systems

  • Technological advancements in extraction and purification improving yield and purity

  • Strategic partnerships between ingredient suppliers and major cosmetic brands

Get Full Report Here: https://www.24chemicalresearch.com/reports/263015/olive-squalene-market

The companies listed above are not only supplying a crucial ingredient—they are pioneering the sustainable evolution of the personal care and pharmaceutical industries.