The Global Sialic Acid Powder Market was valued at USD 198.75 Million in 2024 and is projected to reach USD 325.41 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 8.6% during the forecast period (2024–2030). This impressive growth is driven by rising consumer awareness of the health benefits of sialic acid, increased demand for infant nutrition products, and expanding applications in biopharmaceuticals and cosmetics.

As the health and wellness sector advances, the focus intensifies on the key manufacturers and suppliers who are pioneering the production, purification, and application of this vital nutrient. In this blog, we profile the Top 10 Companies in the Sialic Acid Powder Industry—a combination of established biochemical firms, specialized biotech pioneers, and ingredient suppliers shaping the future of this high-growth market.

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🔟 1. Oryza Oil & Fat Chemical Co., Ltd.

Headquarters: Aichi Prefecture, Japan
Key Offering: High-Purity Sialic Acid Powder (N-Acetylneuraminic Acid)

Oryza is a leading Japanese manufacturer specializing in the extraction and refinement of high-value compounds from natural sources. The company has established itself as a key supplier of high-purity sialic acid powder, primarily derived from natural origins, for the nutraceutical and food industries.

Key Strengths and Initiatives:

• Proprietary extraction and purification technologies ensuring >98% purity

• Strong focus on sustainable and natural sourcing methods

• Strategic partnerships with major infant formula manufacturers globally

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9️⃣ 2. Sanyo Fine Co., Ltd.

Headquarters: Osaka, Japan
Key Offering: Pharmaceutical and Food Grade Sialic Acid

Sanyo Fine is a well-respected Japanese chemical company with a long history in fine chemicals and specialty ingredients. Its expertise in carbohydrate chemistry positions it as a significant player in the sialic acid market, catering to demanding pharmaceutical and high-end food applications.

Key Strengths and Initiatives:

• Advanced synthesis and fermentation capabilities for consistent quality

• Rigorous quality control systems compliant with international standards (GMP, ISO)

• Active in R&D for novel sialic acid derivatives for therapeutic use

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8️⃣ 3. Cabio Bioengineering (Wuhan) Co., Ltd.

Headquarters: Wuhan, Hubei, China
Key Offering: Bio-fermented Sialic Acid Powder

Cabio Biotech is a prominent Chinese biotech firm that leverages advanced microbial fermentation technology to produce sialic acid. This approach offers a scalable and cost-effective alternative to traditional extraction methods, making high-quality sialic acid more accessible.

Key Strengths and Initiatives:

• Pioneer in large-scale fermentation production of N-Acetylneuraminic Acid

• Focus on reducing production costs to expand market penetration

• Expanding production capacity to meet growing global demand

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7️⃣ 4. Hangzhou Higrand Biotech Co., Ltd.

Headquarters: Hangzhou, Zhejiang, China
Key Offering: Sialic Acid Powder for Nutraceuticals and Cosmetics

Higrand Biotech is a specialized manufacturer of high-purity nutritional ingredients, including sialic acid. The company supplies a range of grades suitable for dietary supplements, functional foods, and cosmetic formulations, emphasizing product safety and efficacy.

Key Strengths and Initiatives:

• Comprehensive product portfolio with various purity levels for different applications

• Strong R&D focus on enhancing the bioavailability of sialic acid

• Certifications for quality management and food safety (FSSC 22000, HACCP)

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6️⃣ 5. Ingredia SA

Headquarters: Arras, France
Key Offering: Dairy-derived Bioactive Ingredients, including Sialic Acid-rich Fractions

Ingredia, a global dairy-ingredient leader, offers specialized milk fractions that are naturally rich in sialic acid. While not a pure sialic acid powder supplier, its bioactive ingredient solutions are crucial for infant nutrition and adult wellness products that harness the benefits of sialylated compounds.

Key Strengths and Initiatives:

• Expertise in milk fractionation to concentrate naturally occurring sialic acid

• Strong presence in the infant formula ingredient market

• Commitment to sustainable dairy farming and ingredient traceability

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5️⃣ 6. Zhejiang Kingdomway Biotechnology Co., Ltd.

Headquarters: Shaoxing, Zhejiang, China
Key Offering: Pharmaceutical Intermediates and Bio-Chemicals, including Sialic Acid

Kingdomway is a major manufacturer of pharmaceutical intermediates and fine chemicals. The company produces sialic acid as part of its broad portfolio, serving clients in the pharmaceutical industry who require high-purity building blocks for drug development, particularly for glycobiology-based therapeutics.

Key Strengths and Initiatives:

• Large-scale production capacity for chemical and biochemical products

• Focus on serving the research and pharmaceutical sectors

• Investment in R&D for efficient synthetic pathways

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4️⃣ 7. Biozyme (A Thermo Fisher Scientific Company)

Headquarters: Aachen, Germany / Waltham, Massachusetts, USA
Key Offering: High-Purity Biochemicals for Life Science Research

Biozyme, now part of Thermo Fisher Scientific, is a critical supplier for the life sciences sector. It provides high-purity sialic acid and related glycobiology reagents to academic institutions, research labs, and biopharma companies worldwide, supporting fundamental research and drug discovery.

Key Strengths and Initiatives:

• Unmatched quality and consistency required for critical research applications

• Global distribution network through Thermo Fisher Scientific

• Supporting advancements in glycomics and cell biology research

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3️⃣ 8. Carbosynth Limited

Headquarters: Compton, Berkshire, United Kingdom
Key Offering: Carbohydrates, Nucleosides, and Biochemicals, including Sialic Acid

Carbosynth is a leading global supplier of fine chemicals and biochemicals for research and development. The company offers a range of sialic acid derivatives and related compounds, catering to the needs of scientists in glycobiology, diagnostics, and pharmaceutical development.

Key Strengths and Initiatives:

• Extensive catalog of rare sugars and glycobiology tools

• Custom synthesis services for specialized sialic acid compounds

• Strategic acquisitions to expand product portfolio and global reach

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2️⃣ 9. GlycoMatrix (A Division of Dextra Laboratories)

Headquarters: Reading, United Kingdom
Key Offering: Custom Glycosylation Services and Glycan Building Blocks

GlycoMatrix, part of Dextra Laboratories, specializes in complex carbohydrate chemistry. While primarily a service provider, it is a key enabler in the sialic acid space, offering custom sialylation services and supplying high-value sialic acid-containing compounds for therapeutic and vaccine development.

Key Strengths and Initiatives:

• World-leading expertise in the chemical and enzymatic synthesis of glycans

• Critical supplier for the development of conjugate vaccines and glycoprotein drugs

• Collaborative R&D projects with leading biopharmaceutical companies

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1️⃣ 10. Sigma-Aldrich (Merck KGaA)

Headquarters: Darmstadt, Germany / St. Louis, Missouri, USA
Key Offering: Life Science Reagents and High-Purity Chemicals

As one of the world’s largest suppliers for scientific research, Sigma-Aldrich (now MilliporeSigma under Merck KGaA) is a fundamental source for sialic acid powder. It provides standardized, high-purity sialic acid to thousands of research laboratories, ensuring quality and reproducibility in scientific studies globally.

Key Strengths and Initiatives:

• Extensive quality assurance and regulatory support for research applications

• Global logistics network ensuring reliable supply to the scientific community

• Investment in expanding its portfolio of glycobiology research tools

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🧬 Outlook: The Future of Sialic Acid Powder Is Driven by Innovation and Health Awareness

The sialic acid powder market is experiencing a significant transformation. While traditional applications in infant formula remain the largest segment, the industry is rapidly expanding into new frontiers driven by scientific discovery and consumer health trends.

📈 Key Trends Shaping the Market:

• Rising Demand in Infant Nutrition: Growing global birth rates and increasing parental spending on premium nutrition are fueling demand for sialic-acid-fortified infant formula, as it is a key component of human milk oligosaccharides (HMOs).

• Expansion into Adult Nutraceuticals: Research into sialic acid’s role in cognitive health, immune function, and anti-aging is creating new opportunities in dietary supplements for adults.

• Biopharmaceutical Applications: Sialic acid is critical in the development of biologics, including monoclonal antibodies and vaccines, where it affects the efficacy and stability of therapeutic proteins.

• Technological Advancements in Production: The shift from extraction to more efficient microbial fermentation and enzymatic synthesis is reducing costs and improving sustainability, making sialic acid more accessible for widespread use.

Get Full Report Here:
Sialic Acid Powder Market – View in Detailed Research Report

The companies listed above are not only supplying a critical ingredient—they are enabling advancements in global health, nutrition, and medical science.