The Global Clobutinol Market was valued at USD 28.5 Million in 2023 and is projected to reach USD 38.2 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 3.8% during the forecast period (2024–2030). This steady growth is being fueled by the persistent global prevalence of respiratory conditions, the demand for effective over-the-counter (OTC) cough remedies, and ongoing pharmaceutical R&D targeting improved antitussive therapies.

As the healthcare sector continues to prioritize respiratory health solutions, the focus intensifies on the key manufacturers and suppliers who ensure the quality, safety, and global supply of essential active pharmaceutical ingredients (APIs) like clobutinol hydrochloride. In this blog, we profile the Top 10 Companies in the Clobutinol Industry—a mix of specialized chemical suppliers, pharmaceutical giants, and research entities shaping the production and distribution of this critical cough suppressant.

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🔟 1. Cayman Chemical Company

Headquarters: Ann Arbor, Michigan, USA
Key Offering: High-Purity Clobutinol HCl for Research

Cayman Chemical is a leading global supplier of biochemicals for research, including high-purity clobutinol hydrochloride. The company serves pharmaceutical companies, academic institutions, and contract research organizations (CROs) worldwide, providing the essential building blocks for drug discovery and development.

Research and Development Focus:

• Supply of analytical standards and reference materials

• Support for pharmacological studies on cough reflex mechanisms

• Strict adherence to cGMP and ISO quality standards for research chemicals

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Clobutinol Market – View in Detailed Research Report

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9️⃣ 2. Alfa Chemistry

Headquarters: New York, USA
Key Offering: Clobutinol (CAS 14860-49-2), Pharmaceutical Intermediates

Alfa Chemistry provides a comprehensive portfolio of pharmaceutical intermediates and fine chemicals, including clobutinol. The company supports clients in the pharmaceutical and biotechnology sectors with custom synthesis, process development, and scale-up services.

Research and Development Focus:

• Custom synthesis of clobutinol and its derivatives

• Scale-up support from laboratory to commercial production

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8️⃣ 3. Waterstone Technology

Headquarters: Carmel, Indiana, USA
Key Offering: Clobutinol HCl, Certified Reference Standards

Waterstone Technology specializes in providing high-quality reference standards and pharmaceutical impurities. Their clobutinol offerings are crucial for quality control and analytical testing in pharmaceutical manufacturing, ensuring product safety and regulatory compliance.

Research and Development Focus:

• GMP-grade analytical standards

• Identification and supply of clobutinol-related impurities

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7️⃣ 4. Shanghai T&W Pharmaceutical Co., Ltd.

Headquarters: Shanghai, China
Key Offering: Clobutinol Hydrochloride API, Finished Dosage Forms

Shanghai T&W Pharmaceutical is a significant player in the production of clobutinol hydrochloride as an active pharmaceutical ingredient (API). The company has robust manufacturing capabilities and supplies both the domestic Chinese market and international pharmaceutical clients.

Research and Development Focus:

• Process optimization for cost-effective API manufacturing

• Development of stable clobutinol formulations

Download FREE Sample Report:
Clobutinol Market – View in Detailed Research Report

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6️⃣ 5. Shanghai New Union Textra

Headquarters: Shanghai, China
Key Offering: Pharmaceutical Raw Materials, Clobutinol Base

Shanghai New Union Textra is a chemical supplier specializing in pharmaceutical raw materials and intermediates. The company exports clobutinol and other fine chemicals to global markets, supporting the pharmaceutical supply chain with consistent quality and reliable delivery.

Research and Development Focus:

• Supply chain optimization for global distribution

• Quality assurance for international regulatory standards

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5️⃣ 6. Tokyo Chemical Industry Co., Ltd. (TCI)

Headquarters: Tokyo, Japan
Key Offering: Clobutinol for Research, Laboratory Reagents

TCI is a leading global manufacturer of high-purity laboratory chemicals, including clobutinol. The company serves the research community with high-quality reagents that are essential for early-stage drug discovery and academic research into antitussive agents.

Research and Development Focus:

• High-purity chemical synthesis for research applications

• Support for academic and industrial research partnerships

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4️⃣ 7. BOC Sciences

Headquarters: Shirley, New York, USA
Key Offering: Clobutinol HCl, Pharmaceutical Reference Materials

BOC Sciences provides comprehensive chemical services and products, including clobutinol hydrochloride for pharmaceutical development. The company supports drug development pipelines with reliable API sourcing and analytical services.

Research and Development Focus:

• API sourcing and supply chain management

• Analytical method development and validation services

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3️⃣ 8. ChemScence

Headquarters: Pennsylvania, USA
Key Offering: Clobutinol (CAS 14860-49-2), Custom Synthesis

ChemScence is a chemical manufacturer and supplier that offers clobutinol for research and development purposes. The company focuses on providing researchers with the chemical tools needed for pharmaceutical innovation.

Research and Development Focus:

• Custom chemical synthesis services

• Scale-up capabilities for development quantities

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2️⃣ 9. TargetMol Chemicals Inc.

Headquarters: Boston, Massachusetts, USA
Key Offering: Clobutinol for Screening, Bioactive Compounds

TargetMol provides a wide range of bioactive compounds for drug screening and pharmacological research. Their clobutinol offerings support research into its mechanism of action and potential new therapeutic applications beyond cough suppression.

Research and Development Focus:

• Compound libraries for high-throughput screening

• Support for mechanism-of-action studies

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1️⃣ 10. ApexBio Technology

Headquarters: Houston, Texas, USA
Key Offering: Clobutinol HCl, Inhibitors for Research

ApexBio Technology specializes in providing inhibitors and bioactive molecules for life science research. The company supplies clobutinol to researchers studying its effects on neural pathways involved in the cough reflex and exploring potential repurposing opportunities.

Research and Development Focus:

• Neuroscience and respiratory research applications

• Drug repurposing and new indication discovery

Get Full Report Here:
Clobutinol Market – View in Detailed Research Report

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🌍 Outlook: The Future of Clobutinol Is Rooted in Innovation and Precision

The clobutinol market is experiencing a steady evolution. While traditional cough suppression remains its primary application, the industry is investing in advanced formulation technologies, improved synthesis methods, and exploration of novel therapeutic applications.

📈 Key Trends Shaping the Market:

• Increasing demand for OTC cough remedies in emerging markets

• Advancements in drug delivery systems for improved efficacy

• Growing research into neuromodulatory effects of antitussive agents

• Stringent regulatory requirements driving quality improvements in API manufacturing

Get Full Report Here:
Clobutinol Market – View in Detailed Research Report

The companies listed above are not only supplying a crucial therapeutic agent—they’re advancing our understanding of respiratory pharmacology and contributing to better patient outcomes worldwide.