The Global Electroporation Buffer Market was valued at US$ 183.5 Million in 2022 and is projected to reach US$ 285.7 Million by 2029, growing at a Compound Annual Growth Rate (CAGR) of 6.5% during the forecast period (2023–2029). This robust growth is fueled by the expanding fields of cell therapy, genetic engineering, and drug discovery, where electroporation serves as a critical technique for introducing molecules into cells with high efficiency.

As life sciences research advances toward more sophisticated gene editing and therapeutic applications, the focus intensifies on the specialized buffer solutions that ensure successful cell transfection. In this blog, we profile the Top 10 Companies in the Electroporation Buffer Market—a mix of established life science giants and specialized manufacturers shaping the future of cellular research tools.

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🔟 1. Bio-Rad Laboratories

Headquarters: Hercules, California, USA
Key Offering: Gene Pulser Electroporation Buffers, Sterile Electroporation Cuvettes

Bio-Rad is a global leader in life science research and clinical diagnostics, offering a comprehensive portfolio of electroporation instruments and consumables. Their proprietary electroporation buffers are optimized for a wide range of cell types, from bacteria and yeast to mammalian and plant cells, ensuring high transfection efficiency and cell viability. The company’s dedication to R&D keeps it at the forefront of protocol development.

Innovation Focus:

• Development of high-efficiency, low-toxicity buffer formulations
• Integrated systems combining electroporators with optimized buffers
• Support for CRISPR gene editing and other advanced applications

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9️⃣ 2. Thermo Fisher Scientific

Headquarters: Waltham, Massachusetts, USA
Key Offering: Neon Transfection System buffers, Cell Line Specific Electroporation Kits

Thermo Fisher Scientific provides a vast array of reagents and instruments for genetic analysis. Their electroporation buffer solutions are engineered to work seamlessly with their advanced transfection systems, such as the Neon Transfection System, which is renowned for its high efficiency with challenging cell lines, including primary cells and stem cells. The company leverages its scale to ensure consistent, high-quality buffer production.

Innovation Focus:

• Kits tailored for specific cell lines and applications
• Focus on scalability from research to clinical manufacturing
• Integration with Gibco cell culture media for enhanced performance

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8️⃣ 3. Lonza Group AG

Headquarters: Basel, Switzerland
Key Offering: Nucleofector^TM Kits & Solutions

Lonza is a dominant force in the transfection market with its innovative Nucleofector^TM Technology. This system utilizes specialized, cell-type specific buffers combined with electrical parameters to directly deliver nucleic acids to the nucleus, bypassing the cytoplasm. This proprietary approach is particularly valuable for hard-to-transfect cells and is a cornerstone technology in cell and gene therapy development.

Innovation Focus:

• Proprietary buffer formulations for non-viral cell engineering
• Strong presence in the clinical and therapeutic markets
• Continuous development of new kits for emerging cell types

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7️⃣ 4. Merck KGaA

Headquarters: Darmstadt, Germany
Key Offering: SAFC^® Electroporation Buffers, GenJet™ Reagents

Through its MilliporeSigma division, Merck offers high-purity electroporation buffers and related reagents. The company caters to both basic research and bioproduction needs, providing buffers that are rigorously tested for performance and consistency. Their products are trusted in GMP environments, supporting the transition of therapies from the lab to the clinic.

Innovation Focus:

• Supply of GMP-grade raw materials and buffers
• Focus on supporting scalable therapeutic production
• Extensive technical support and protocol optimization services

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6️⃣ 5. MaxCyte, Inc.

Headquarters: Gaithersburg, Maryland, USA
Key Offering: MaxCyte Electroporation Buffer, EXO Electroporation Buffer

MaxCyte specializes in large-scale, clinical-grade cell engineering. Its proprietary flow electroporation technology is paired with optimized buffers designed to handle large volumes of cells with minimal damage, making it ideal for CAR-T and other cell therapy manufacturing. The company’s buffers are a critical component of their closed-system processing platforms.

Innovation Focus:

• Buffers for scalable, clinical-stage cell therapy manufacturing
• Specialized buffers for exosome and extracellular vesicle loading
• Strong IP portfolio around electroporation processes

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5️⃣ 6. Mirus Bio LLC (Acquired by Bio-Techne)

Headquarters: Madison, Wisconsin, USA
Key Offering: Ingenio^® Electroporation Solution, TransIT^® Electroporation Buffer

Mirus Bio, now part of Bio-Techne, has a long history of innovation in nucleic acid delivery. Their Ingenio^® Electroporation Solution is a versatile, serum-free formulation designed to maximize DNA delivery and cell survival across many common cell lines. The company is known for its user-friendly protocols and high-performance reagents.

Innovation Focus:

• Development of low-toxicity, high-performance formulations
• Integration with Bio-Techne’s broader portfolio of research tools
• Focus on reproducibility and ease of use for researchers

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Electroporation Buffer Market – View in Detailed Research Report

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4️⃣ 7. Harvard Bioscience, Inc. (BTX)

Headquarters: Holliston, Massachusetts, USA
Key Offering: BTXpress^™ Electroporation Buffer, HyClone Electroporation Enhancer

Harvard Bioscience, through its BTX brand, has been a pioneer in electroporation technology for decades. They offer a range of buffers and enhancers designed to work with their electroporation systems. Their products are widely used in basic research, particularly in molecular biology and neuroscience applications, known for their reliability and effectiveness.

Innovation Focus:

• Long-standing expertise in electroporation protocol development
• Buffers for specialized applications like in vivo electroporation
• Reliable consumables for core research facilities

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3️⃣ 8. Altogen Biosystems

Headquarters: Austin, Texas, USA
Key Offering: Custom Electroporation Buffers, Cell-Type Specific Kits

Altogen Biosystems is a specialized provider of transfection reagents and services. They offer a variety of electroporation buffers, including custom formulations tailored to specific research needs. Their focus on providing solutions for hard-to-transfect cell lines makes them a valuable partner for researchers tackling complex genetic manipulation challenges.

Innovation Focus:

• Custom buffer formulation services
• Kits optimized for difficult cell types (e.g., primary neurons, immune cells)
• Combination with RNAi and CRISPR screening services

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2️⃣ 9. Teknova

Headquarters: Hollister, California, USA
Key Offering: Molecular Biology Grade Buffers, Custom Electroporation Solutions

Teknova is known for its high-quality prepared media and reagents for the life sciences industry. They offer sterile, ready-to-use electroporation buffers in various sizes, ensuring consistency and saving researchers valuable time. Their commitment to quality control makes their products a trusted choice for applications requiring high reproducibility.

Innovation Focus:

• High-purity, ready-to-use buffer solutions
• Scalable offerings from small research vials to bulk manufacturing
• Rigorous quality control for batch-to-batch consistency

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1️⃣ 10. Biochrom AG (a part of Sartorius)

Headquarters: Berlin, Germany
Key Offering: TAE and TBE Buffers, Specialty Electroporation Salts

Biochrom, now fully integrated into Sartorius, provides essential biochemicals and buffer solutions for laboratories worldwide. While offering standard molecular biology buffers (like TAE and TBE), they also supply the high-quality salt components and base solutions used by researchers to formulate their own custom electroporation buffers, catering to labs that require specific ionic conditions for optimal results.

Innovation Focus:

• Supply of high-purity raw materials for buffer formulation
• Integration into Sartorius’s bioprocess solutions portfolio
• Focus on fundamental reagents supporting a wide range of research

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🧬 Outlook: The Future of Electroporation Is Efficient and Accessible

The electroporation buffer market is evolving beyond a supporting reagent to a fundamental enabler of next-generation biotechnologies. While standard formulations remain essential, the drive is towards specialized, high-performance solutions that maximize cell viability and transfection efficiency for advanced applications.

📈 Key Trends Shaping the Market:

• Growing demand for GMP-grade buffers for cell and gene therapy manufacturing
• Customization of buffer formulations for novel cell types and cargoes (e.g., mRNA, RNPs)
• Integration of buffer systems with automated, high-throughput electroporation platforms
• Increased focus on minimizing cytotoxicity to improve the quality of engineered cells

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Electroporation Buffer Market – View in Detailed Research Report

The companies listed above are not only supplying critical research tools—they are actively advancing the capabilities of genetic engineering and therapeutic development worldwide.