The Global Covalent Organic Frameworks (COFs) Market was valued at USD 78.5 Million in 2024 and is projected to reach USD 215.3 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 18.2% during the forecast period (2024–2030). This remarkable growth is being driven by increasing demand for advanced porous materials in gas storage, catalysis, and energy storage applications, coupled with rising R&D investments from both academic institutions and industrial players.

As the materials science industry advances toward highly efficient and customizable nanoporous structures, the focus shifts to the pioneering companies developing and supplying these sophisticated materials. In this blog, we profile the Top 10 Companies in the Covalent Organic Frameworks Industry—a mix of specialized chemical suppliers, research-focused firms, and emerging manufacturers defining the future of functional organic materials.

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🔟 1. ACS Material

Headquarters: Pasadena, California, USA
Key Offering: 2D and 3D COF powders, custom synthesis services, R&D quantities

ACS Material is a leading global supplier of advanced materials, including a comprehensive portfolio of high-purity Covalent Organic Frameworks. The company provides materials for academic research and early-stage industrial development, with a strong focus on quality and consistency. Their product lines support applications in sensing, catalysis, and gas separation.

Innovation Initiatives:

• Development of novel COF structures with enhanced surface areas

• Collaborations with top-tier universities for material validation

• Scaling up synthesis processes for commercial availability

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9️⃣ 2. Lumtec

Headquarters: Hsinchu, Taiwan
Key Offering: Optoelectronics-grade COFs, luminescent frameworks, thin film materials

Lumtec specializes in organic electronic materials and has expanded into functional COFs designed for optoelectronic applications. Their materials exhibit high charge carrier mobility and tailored band gaps, making them suitable for next-generation OLEDs, photovoltaics, and sensors. The company serves the display and semiconductor industries.

Innovation Initiatives:

• Proprietary synthesis of photoactive COFs

• Integration of COFs into device architectures

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8️⃣ 3. April Scientific

Headquarters: Suzhou, China
Key Offering: Chromatography COFs, separation media, analytical standard materials

April Scientific focuses on the application of COFs in separation sciences. The company develops highly ordered porous materials for gas chromatography, solid-phase extraction, and HPLC columns. Their products offer superior separation efficiency compared to traditional stationary phases, attracting interest from the pharmaceutical and environmental testing sectors.

Innovation Initiatives:

• COF-based stationary phases for analytical instruments

• Custom COF design for specific separation challenges

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7️⃣ 4. Shanghai Kaishu Chemical Technology Co., Ltd.

Headquarters: Shanghai, China
Key Offering: Bulk COF powders, catalyst supports, adsorbent materials

Shanghai Kaishu is a chemical technology company supplying various advanced materials, including Covalent Organic Frameworks for industrial applications. They focus on cost-effective production methods to make COFs more accessible for large-scale uses such as hazardous gas removal and catalytic processes in chemical manufacturing.

Innovation Initiatives:

• Scale-up of solvent-free synthesis routes

• Development of COF composites for enhanced mechanical stability

Download FREE Sample Report:
Global Covalent Organic Frameworks Market – View in Detailed Research Report

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6️⃣ 5. Shanghai Tensus BioTech Co., Ltd.

Headquarters: Shanghai, China
Key Offering: Biocompatible COFs, drug delivery systems, diagnostic materials

Shanghai Tensus BioTech specializes in applying nanotechnology to biomedical challenges. Their COF portfolio includes materials designed for controlled drug release, biosensing, and bioimaging. These frameworks offer high loading capacities and tunable release profiles, making them promising candidates for advanced therapeutic applications.

Innovation Initiatives:

• Functionalization of COFs for targeted drug delivery

• Development of COF-based contrast agents

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5️⃣ 6. Nanjing Sanhao Chemical Co., Ltd.

Headquarters: Nanjing, China
Key Offering: Standard COF materials, building blocks for COF synthesis, R&D kits

Nanjing Sanhao Chemical supplies chemical reagents and advanced materials to research institutions and industrial laboratories worldwide. Their COF products include both ready-to-use materials and the molecular building blocks necessary for custom framework synthesis, supporting the growing ecosystem of COF researchers.

Innovation Initiatives:

• Expansion of COF building block library

• Development of user-friendly COF synthesis kits

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4️⃣ 7. Sigma-Aldrich (Merck KGaA)

Headquarters: Darmstadt, Germany
Key Offering: Research-grade COFs, high-purity materials, analytical standards

As part of the global life science leader Merck KGaA, Sigma-Aldrich offers a range of Covalent Organic Frameworks through its extensive distribution network. The company provides materials that meet rigorous quality standards required by academic and industrial researchers, supported by comprehensive technical data and characterization.

Innovation Initiatives:

• Quality assurance protocols for batch-to-batch consistency

• Collaboration with academic pioneers in COF research

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3️⃣ 8. TCI Chemicals

Headquarters: Tokyo, Japan
Key Offering: Specialty COFs, functional organic materials, custom synthesis

Tokyo Chemical Industry (TCI) is a leading supplier of high-purity organic chemicals, including emerging materials like COFs. The company offers several standard COF structures and provides custom synthesis services for research organizations developing novel applications in energy storage and environmental remediation.

Innovation Initiatives:

• Development of electrically conductive COFs

• Expansion of COF offerings for battery applications

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2️⃣ 9. Alfa Aesar (Thermo Fisher Scientific)

Headquarters: Haverhill, Massachusetts, USA
Key Offering: Catalog COFs, material science products, laboratory chemicals

Alfa Aesar, a Thermo Fisher Scientific company, supplies a wide range of research chemicals and materials, including select Covalent Organic Frameworks. Their global distribution capability ensures researchers worldwide have access to these advanced materials, supported by the company’s extensive quality control and technical support infrastructure.

Innovation Initiatives:

• Integration of COFs into broader materials portfolio

• Support for academic and industrial research partnerships

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1️⃣ 10. Strem Chemicals, Inc.

Headquarters: Newburyport, Massachusetts, USA
Key Offering: High-performance COFs, catalyst precursors, specialty materials

Strem Chemicals specializes in high-purity materials for catalysis and materials science research. Their entry into the COF market focuses on frameworks designed for catalytic applications, leveraging the high surface area and tunable functionality of COFs to create superior heterogeneous catalysts for chemical synthesis and energy conversion.

Innovation Initiatives:

• Development of COF-supported catalyst systems

• Exploration of COFs in electrocatalysis and photocatalysis

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Global Covalent Organic Frameworks Market – View in Detailed Research Report

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🌍 Outlook: The Future of Covalent Organic Frameworks Is Multifunctional and Scalable

The Covalent Organic Frameworks market is experiencing a transformative phase. While research-grade materials currently dominate, the industry is rapidly advancing toward commercial-scale production and application-specific designs that will unlock their full potential across multiple industries.

📈 Key Trends Shaping the Market:

• Accelerated R&D in COF-based batteries and supercapacitors for enhanced energy storage

• Increasing adoption of COFs in environmental applications for carbon capture and water purification

• Advancements in synthesis methodologies reducing production costs and improving material quality

• Growing pharmaceutical interest in COFs for drug delivery and biomedical imaging

Get Full Report Here:
Global Covalent Organic Frameworks Market – View in Detailed Research Report

The companies listed above are not only supplying advanced materials—they’re enabling the next generation of technological innovation across energy, healthcare, and environmental sectors.