The Global 2-Methyl Tetrahydrofuran (2-MeTHF) Market was valued at USD 485.6 Million in 2024 and is projected to reach USD 742.3 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 6.8% during the forecast period (2024–2030). This robust growth is fueled by the compound’s expanding applications as a green solvent in pharmaceuticals, agrochemicals, and polymer production, alongside its rising role as a bio-based platform chemical replacing traditional petrochemical derivatives.

As industries worldwide intensify their focus on sustainability and regulatory compliance, 2-MeTHF has emerged as a critical enabler for greener chemical processes. In this blog, we profile the Top 10 Companies in the 2-Methyl Tetrahydrofuran Industry—a dynamic mix of chemical giants, specialty producers, and bio-refining innovators who are shaping the supply and technological advancement of this versatile solvent.

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🔟 1. BASF SE

Headquarters: Ludwigshafen, Germany
Key Offering: High-Purity 2-MeTHF, Derivative Intermediates

BASF is a global chemical leader and a major producer of 2-Methyl Tetrahydrofuran, leveraging its extensive petrochemical and renewable feedstocks. The company supplies high-purity 2-MeTHF to the pharmaceutical and specialty chemicals sectors, emphasizing its advantages as a low-toxicity, biodegradable solvent.

Sustainability & Innovation Initiatives:

• Development of bio-based routes to 2-MeTHF from renewable raw materials

• Integration into circular economy models for solvent recovery and reuse

• Commitment to carbon-neutral growth by 2050

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9️⃣ 2. Ashland Global Holdings Inc.

Headquarters: Wilmington, Delaware, USA
Key Offering: Pharmaceutical-Grade 2-MeTHF, Specialty Solvents

Ashland is a prominent supplier of high-performance chemicals, including high-purity 2-MeTHF tailored for sensitive applications like pharmaceutical synthesis and electronic chemical formulations. Their focus on stringent quality control makes them a preferred partner for regulated industries.

Sustainability & Innovation Initiatives:

• Investment in green chemistry solutions that reduce environmental impact

• Collaborations with pharmaceutical companies to optimize solvent systems

Download FREE Sample Report:
Global 2-Methyl Tetrahydrofuran Market – View in Detailed Research Report

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8️⃣ 3. Mitsubishi Chemical Corporation

Headquarters: Tokyo, Japan
Key Offering: 2-MeTHF, Furfural Derivatives, Bio-Chemicals

Mitsubishi Chemical is a key player in the Asian 2-MeTHF market, with strong capabilities in producing the solvent from furfural, a biomass-derived chemical. The company serves a broad industrial base, including the chemical, electronic, and automotive sectors.

Sustainability & Innovation Initiatives:

• Pioneering biomass-based chemical production pathways

• Expansion of sustainable product portfolios under its KAITEKI vision

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7️⃣ 4. Avantium N.V.

Headquarters: Amsterdam, Netherlands
Key Offering: YXY® platform chemicals, Bio-based 2-MeTHF

Avantium is a leading renewable chemistry company renowned for its YXY® technology, which converts plant-based sugars into FDCA (furandicarboxylic acid) and other derivatives, including bio-based 2-MeTHF. The company positions 2-MeTHF as a cornerstone of its green solvent offerings.

Sustainability & Innovation Initiatives:

• World’s first commercial plant for FDCA and derivative chemicals

• Strategic focus on 100% plant-based, recyclable materials

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6️⃣ 5. Saudi International Petrochemical Company (SIPCHEM)

Headquarters: Al-Khobar, Saudi Arabia
Key Offering: 2-MeTHF, Tetrahydrofuran (THF), Acetylene-based Chemicals

SIPCHEM is a major petrochemical producer in the Middle East with a significant presence in the Tetrahydrofuran market, which includes 2-MeTHF production. The company benefits from integrated acetylene and formaldehyde production, providing a cost-advantaged position.

Sustainability & Innovation Initiatives:

• Diversification into specialty chemicals with lower environmental footprints

• Investments in efficiency improvements and carbon management

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5️⃣ 6. Penn A Kem LLC (a division of INEOS)

Headquarters: Memphis, Tennessee, USA
Key Offering: High-Purity 2-MeTHF, Pyrrolidones, N-Methyl-2-pyrrolidone (NMP)

Penn A Kem, part of the INEOS group, is a leading North American producer of high-purity solvents, including 2-Methyl Tetrahydrofuran. The company serves demanding markets such as electronics, agrochemicals, and pharmaceuticals with a strong focus on supply chain reliability.

Sustainability & Innovation Initiatives:

• Development of solvent recovery and recycling technologies

• Adherence to Responsible Care® principles for chemical safety and sustainability

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4️⃣ 7. Hongye Chemical Co., Ltd.

Headquarters: Shandong, China
Key Offering: 2-MeTHF, THF, PTMEG

Hongye Chemical is a significant Chinese manufacturer of tetrahydrofuran and its derivatives, including 2-MeTHF. The company has a strong domestic market share and is expanding its international footprint, catering to the growing demand for solvents in Asia-Pacific’s manufacturing sectors.

Sustainability & Innovation Initiatives:

• Capacity expansion to meet regional demand growth

• Focus on process optimization and waste reduction

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3️⃣ 8. Dairen Chemical Corporation (DCC)

Headquarters: Taipei, Taiwan
Key Offering: 2-MeTHF, BDO, GBL, THF

Dairen Chemical is a major global producer in the butanediol (BDO) value chain, with integrated production of Tetrahydrofuran and 2-Methyl Tetrahydrofuran. The company’s strong technological base and large-scale production make it a key supplier to the polymer and chemical industries.

Sustainability & Innovation Initiatives:

• Leading producer using advanced catalyst technologies for higher yields

• Commitment to environmental protection and sustainable manufacturing

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Global 2-Methyl Tetrahydrofuran Market – View in Detailed Research Report

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2️⃣ 9. TCC Chemical Corporation

Headquarters: Taipei, Taiwan
Key Offering: Specialty 2-MeTHF, Fine Chemicals, Solvents

TCC Chemical is a specialty chemical company with a diverse portfolio that includes high-quality 2-Methyl Tetrahydrofuran. The company focuses on serving niche markets with high-purity products, particularly in the electronics and pharmaceutical sectors.

Sustainability & Innovation Initiatives:

• R&D focus on high-value, low-environmental-impact chemicals

• Implementation of green chemistry principles across operations

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1️⃣ 10. Corbion N.V.

Headquarters: Amsterdam, Netherlands
Key Offering: Bio-based Chemicals, Lactic Acid, Potential for Bio-2-MeTHF

Corbion is a frontrunner in bio-based chemicals, primarily known for its lactic acid and polylactic acid (PLA). While not a direct producer, the company’s advanced fermentation technology platform positions it as a potential key player in developing sustainable, bio-based routes to 2-MeTHF and other derivatives.

Sustainability & Innovation Initiatives:

• Global leader in renewable chemistry with a focus on circular solutions

• Active R&D in converting sugar feedstocks into a wider range of bio-chemicals

Read Full Report:
Global 2-Methyl Tetrahydrofuran Market – View in Detailed Research Report

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🌍 Outlook: The Future of 2-Methyl Tetrahydrofuran Is Sustainable and Versatile

The 2-Methyl Tetrahydrofuran market is experiencing a significant transformation. While traditional production methods still dominate, the industry is increasingly investing in bio-based production pathways, process intensification, and exploring novel applications that leverage the solvent’s unique properties.

📈 Key Trends Shaping the Market:

• Accelerated shift from hazardous solvents like dichloromethane to safer alternatives like 2-MeTHF in pharmaceutical manufacturing

• Growing demand for bio-based and renewable solvents driven by stringent environmental regulations in North America and Europe

• Expansion of production capacities in Asia-Pacific, particularly China, to serve local electronics and chemical industries

• Increased R&D into 2-MeTHF’s use as a reaction medium for polymerizations and as a component in battery electrolytes

The companies listed above are not only supplying a critical chemical intermediate—they are actively enabling the green transformation of multiple global industries.

Read Full Report:
Global 2-Methyl Tetrahydrofuran Market – View in Detailed Research Report