The Global Menaquinones Market was valued at USD 245.3 Million in 2023 and is projected to reach USD 386.7 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 6.7% during the forecast period (2024–2030). This robust growth is primarily driven by increasing consumer awareness of bone and cardiovascular health, rising demand for nutraceuticals and fortified foods, and growing clinical validation for the superior bioavailability of Vitamin K2 (Menaquinones) over Vitamin K1.

As the health and wellness industry intensifies its focus on preventative healthcare and specialized nutrition, the key manufacturers of Menaquinones are driving innovation, research, and the development of high-purity, bioavailable forms. This blog profiles the Top 10 Companies in the Menaquinones Industry—a group of biotechnology firms, ingredient specialists, and pharmaceutical leaders shaping the future of this vital nutrient market.

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🔟 1. Kappa Bioscience AS

Headquarters: Oslo, Norway
Key Offering: K2VITAL® (MK-7)

Kappa Bioscience is a globally recognized leader dedicated exclusively to the production of high-purity Vitamin K2 as MK-7. Their flagship product, K2VITAL®, is renowned for its stability, bioavailability, and is a preferred ingredient for dietary supplements and functional foods worldwide.

Innovation and Market Position:

• World’s first and largest specialized producer of synthetic Vitamin K2 (MK-7)

• Strong IP portfolio with numerous patents on production and formulation

• Focus on clinical research to expand application claims

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9️⃣ 2. NattoPharma ASA

Headquarters: Oslo, Norway
Key Offering: MenaQ7® (MK-7)

NattoPharma, a subsidiary of Gnosis by Lesaffre, is a pioneer in the Vitamin K2 market. The company has invested heavily in clinical research to substantiate the health benefits of its MenaQ7® brand, establishing it as a scientifically-backed ingredient for bone and heart health.

Innovation and Market Position:

• Extensive portfolio of human clinical trials supporting MenaQ7® efficacy

• Strategic focus on pharmaceutical and high-dose supplement applications

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8️⃣ 3. Gnosis by Lesaffre

Headquarters: Marcq-en-Barœul, France
Key Offering: MenaQ7® (MK-7), MenaQ7® PURE (all-trans MK-7)

Gnosis by Lesaffre utilizes yeast fermentation, a natural and sustainable process, to produce its Menaquinones. This biotech approach positions them as a key player in providing bio-optimized nutrients, including their high-purity MenaQ7® range.

Innovation and Market Position:

• Specialization in bio-fermentation for natural ingredient production

• Integration of NattoPharma’s research and commercial assets

• Strong global distribution network through the Lesaffre group

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7️⃣ 4. Royal DSM N.V.

Headquarters: Heerlen, Netherlands
Key Offering: MenaquinGold® (MK-7), various Vitamin K blends

DSM is a global science-based company active in health, nutrition, and bioscience. Its MenaquinGold® is a naturally fermented Vitamin K2 (MK-7) ingredient, backed by DSM’s extensive research capabilities and global reach in the human and animal nutrition markets.

Innovation and Market Position:

• Leverages global scale and deep R&D in nutritional science

• Offers integrated solutions combining Vitamin K2 with Vitamin D3

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6️⃣ 5. Viridis BioPharma Pvt. Ltd.

Headquarters: Mumbai, India
Key Offering: MK-4, MK-7

Viridis BioPharma is a significant player in the Asian market, specializing in the manufacturing and supply of pharmaceutical-grade ingredients, including various forms of Menaquinones. The company serves both domestic and international markets with a focus on quality and compliance.

Innovation and Market Position:

• Strong presence in the rapidly growing Asia-Pacific nutraceutical sector

• Focus on cost-effective production while maintaining high-quality standards

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5️⃣ 6. International Flavors & Fragrances Inc. (IFF)

Headquarters: New York, USA
Key Offering: Vitamin K2 (MK-7) through its Health & Biosciences division

Following its merger with DuPont’s Nutrition & Biosciences unit, IFF became a powerhouse in health and wellness ingredients. The company offers Vitamin K2 solutions that cater to the dietary supplement and food fortification markets, leveraging its extensive application expertise.

Innovation and Market Position:

• Extensive portfolio of food, health, and bioscience ingredients

• Ability to create synergistic ingredient systems for targeted health benefits

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4️⃣ 7. DuPont Nutrition & Biosciences (Now part of IFF)

Headquarters: Wilmington, Delaware, USA
Key Offering: MARINTEK® M Vitamin K2 (MK-7)

DuPont (now integrated into IFF) developed MARINTEK® M, a marine-based, all-trans Vitamin K2 (MK-7) produced through a proprietary bacterial fermentation process. This highlights the innovative approaches being used to create sustainable and effective Menaquinone ingredients.

Innovation and Market Position:

• Unique, sustainable sourcing from marine microorganisms

• Strong scientific backing and technical support for customers

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3️⃣ 8. GeneFerm Biotechnology Co., Ltd.

Headquarters: Taoyuan City, Taiwan
Key Offering: FermK2® (MK-7)

GeneFerm Biotechnology is a leading Asian manufacturer specializing in fermentation-derived ingredients. Its FermK2® product is a highly pure, all-trans Vitamin K2 (MK-7) produced via a proprietary microbial fermentation technology, serving global markets.

Innovation and Market Position:

• Expertise in precision fermentation for high-value nutraceuticals

• Strategic position to cater to the high-demand Asia-Pacific region

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2️⃣ 9. Kyowa Hakko Bio Co., Ltd.

Headquarters: Tokyo, Japan
Key Offering: Vitamin K2 (MK-4)

Kyowa Hakko Bio, a member of the Kirin Group, is a world-leading innovator in fermented ingredients. The company produces a range of bioactive compounds, including Vitamin K2 (MK-4), utilizing its advanced fermentation technology and expertise.

Innovation and Market Position:

• Long-standing reputation for quality and reliability in bio-based chemicals

• Strong foothold in the pharmaceutical and nutraceutical industries

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1️⃣ 10. BASF SE

Headquarters: Ludwigshafen, Germany
Key Offering: Vitamin K2 as part of its human nutrition portfolio

As one of the world’s largest chemical producers, BASF offers a comprehensive range of vitamins and nutrients. While historically stronger in Vitamin K1, BASF has a significant presence in the broader vitamin market and the capability to be a major supplier of Menaquinones, leveraging its massive production scale and global distribution.

Innovation and Market Position:

• Global leadership in vitamins and human nutrition ingredients

• Extensive R&D resources and commitment to sustainability

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🌍 Outlook: The Future of Menaquinones is Driven by Science and Synergy

The Menaquinones market is experiencing a significant transformation, moving from a niche ingredient to a mainstream essential nutrient. The future will be shaped by deeper scientific understanding, innovative delivery formats, and strategic combinations with other vital nutrients.

📈 Key Trends Shaping the Market:

• Increased Clinical Research: A growing body of evidence is solidifying the role of MK-7 in cardiovascular and bone health, driving adoption in pharmaceutical applications.

• Food Fortification Expansion: Beyond supplements, Menaquinones are increasingly being incorporated into dairy products, beverages, and bakery items to address widespread nutritional deficiencies.

• Synergistic Formulations: Combination products featuring Vitamin K2 with Vitamin D3 and Calcium are becoming standard for bone health, creating significant market opportunities.

• Advancements in Fermentation Technology: Continuous improvements in microbial fermentation are leading to higher yields, purer forms (all-trans MK-7), and more cost-effective production.

Get Full Report Here:
Menaquinones Market – View in Detailed Research Report

The companies leading the Menaquinones market are not just supplying an ingredient—they are at the forefront of a nutritional revolution, empowering healthier aging and preventative healthcare worldwide.