The Global 1,5-pentanediamine (Cadaverine) Market was valued at USD 26 Million in 2024 and is projected to reach USD 32 Million by 2032, growing at a Compound Annual Growth Rate (CAGR) of 3.1% during the forecast period (2024–2032). This growth is being driven by expanding applications in bio-based polyamides, rising demand from the pharmaceutical sector, and increasing investments in sustainable chemical production.

As the global chemical industry shifts toward bio-based and sustainable materials, the spotlight is on the key producers who are driving innovation, production efficiency, and cleaner chemical pathways. In this blog, we profile the Top 10 Companies in the 1,5-pentanediamine (Cadaverine) Industry—a mix of biotech pioneers, chemical majors, and specialty suppliers shaping the future of this vital biochemical intermediate.

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🔟 1. Cathay Biotech Inc.

Headquarters: Shanghai, China
Key Offering: High-Purity 1,5-pentanediamine, Bio-based Polyamide Intermediates

Cathay Biotech is the undisputed global leader in the cadaverine market, commanding approximately 90% of global production capacity. The company leverages advanced microbial fermentation technology to produce high-purity 1,5-pentanediamine from renewable feedstocks, primarily serving the burgeoning bio-based polyamide (nylon 5X) industry. Their vertically integrated operations, from lysine production to diamine synthesis, provide a significant competitive advantage in cost and supply stability.

Innovation Initiatives:

• Proprietary fermentation strains with high yield efficiency

• Strategic partnerships with global polymer manufacturers

• Continuous R&D investment exceeding 5% of annual revenue

Download FREE Sample Report: 1,5-pentanediamine (Cadaverine) Market – View in Detailed Research Report

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9️⃣ 2. Ningxia Eppen Biotechnology Co., Ltd.

Headquarters: Ningxia, China
Key Offering: Industrial-Grade Cadaverine, Chemical Intermediates

Ningxia Eppen Biotechnology holds the position as the second-largest producer globally, capturing approximately 7% of the market share. The company specializes in the large-scale production of 1,5-pentanediamine through biological fermentation processes, with a strong focus on the Chinese domestic market and export opportunities across Asia. Their strategic location in China’s major chemical production corridor provides access to key infrastructure and raw materials.

Innovation Initiatives:

• Expansion of production capacity to meet growing bio-polymer demand

• Development of customized purity grades for specific applications

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8️⃣ 3. Thermo Fisher Scientific Inc.

Headquarters: Waltham, Massachusetts, USA
Key Offering: Reagent-Grade Cadaverine, Laboratory Chemicals

Thermo Fisher Scientific serves the high-purity segment of the cadaverine market, providing research-grade 1,5-pentanediamine for pharmaceutical, academic, and industrial R&D applications. While not a bulk producer, the company plays a critical role in supplying the high-value research market with consistently pure and well-characterized products that meet rigorous analytical standards.

Innovation Initiatives:

• Stringent quality control for scientific and pharmaceutical applications

• Global distribution network ensuring reliable supply to research institutions

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7️⃣ 4. Merck KGaA (Sigma-Aldrich)

Headquarters: Darmstadt, Germany
Key Offering: High-Purity Cadaverine, Biochemical Reagents

Merck KGaA, operating through its Sigma-Aldrich brand, is a leading global supplier of high-purity chemicals for research and development. The company provides 1,5-pentanediamine in various purity grades tailored for laboratory use, pharmaceutical research, and specialty chemical applications, with a strong emphasis on product consistency and technical support.

Innovation Initiatives:

• Development of specialized grades for pharmaceutical applications

• Comprehensive documentation and regulatory support for research customers

Download FREE Sample Report: 1,5-pentanediamine (Cadaverine) Market – View in Detailed Research Report

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6️⃣ 5. Ajinomoto Co., Inc.

Headquarters: Tokyo, Japan
Key Offering: Amino Acid Derivatives, Biochemical Intermediates

Ajinomoto, traditionally known for its amino acid production, has expanded into specialty biochemicals including 1,5-pentanediamine. The company leverages its extensive expertise in fermentation technology and amino acid chemistry to produce high-quality cadaverine, primarily for the Asian market and specialty applications in pharmaceuticals and fine chemicals.

Innovation Initiatives:

• Integration of cadaverine production with existing amino acid infrastructure

• Focus on sustainable production methods and green chemistry principles

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5️⃣ 6. BOC Sciences

Headquarters: Shirley, New York, USA
Key Offering: Custom Synthesis, Pharmaceutical Intermediates

BOC Sciences operates as a specialty chemical supplier providing 1,5-pentanediamine for research and development purposes. The company focuses on serving the pharmaceutical and biotechnology sectors with high-purity intermediates, offering custom synthesis services and kilogram-scale quantities for drug development and process optimization.

Innovation Initiatives:

• Custom synthesis capabilities for specialized derivative development

• Technical support for pharmaceutical application development

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4️⃣ 7. Toray Industries, Inc.

Headquarters: Tokyo, Japan
Key Offering: Advanced Materials, Bio-based Polymers

Toray Industries, while primarily a consumer of 1,5-pentanediamine for its bio-based polyamide production, maintains strategic involvement in the supply chain through partnerships and technical collaborations. The company’s extensive research in polymer science drives demand for high-quality cadaverine as a building block for sustainable materials.

Innovation Initiatives:

• Development of novel polyamide 5X materials using cadaverine

• Collaborative R&D with suppliers to optimize diamine quality and consistency

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3️⃣ 8. BASF SE

Headquarters: Ludwigshafen, Germany
Key Offering: Chemical Intermediates, Performance Materials

BASF maintains a presence in the specialty chemicals market with capabilities in diamine production and applications. While not a primary producer of 1,5-pentanediamine, the company’s extensive chemical portfolio and application expertise position it as a significant player in downstream markets and potential future capacity expansion.

Innovation Initiatives:

• Research into novel applications for bio-based diamines

• Development of sustainable material solutions incorporating cadaverine derivatives

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2️⃣ 9. Shanghai BioSun Biotechnology Co., Ltd.

Headquarters: Shanghai, China
Key Offering: Biochemical Intermediates, Custom Fermentation

Shanghai BioSun Biotechnology is an emerging player in the Chinese biochemical market with capabilities in 1,5-pentanediamine production. The company focuses on serving domestic demand for bio-based chemical intermediates while exploring export opportunities in the Asian region.

Innovation Initiatives:

• Expansion of fermentation capacity for specialty chemicals

• Development of cost-effective production processes

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1️⃣ 10. Hangzhou Hyper Chemicals Limited

Headquarters: Hangzhou, China
Key Offering: Fine Chemicals, Pharmaceutical Intermediates

Hangzhou Hyper Chemicals operates as a specialty chemical supplier with capabilities in 1,5-pentanediamine production and distribution. The company serves both domestic Chinese markets and international customers with a focus on quality consistency and reliable supply chain management.

Innovation Initiatives:

• Quality enhancement initiatives for international market compliance

• Development of application-specific product grades

Get Full Report Here: 1,5-pentanediamine (Cadaverine) Market – View in Detailed Research Report

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🚀 Outlook: The Future of 1,5-pentanediamine Is Sustainable and Application-Driven

The 1,5-pentanediamine market is undergoing a significant transformation. While traditional applications continue to drive volume, the industry is increasingly focused on bio-based production methods, advanced purification technologies, and expansion into high-value applications.

📈 Key Trends Shaping the Market:

• Rapid capacity expansion in China to meet growing bio-polyamide demand

• Increasing R&D investment in pharmaceutical and agricultural applications

• Advancements in fermentation technology improving yield and reducing costs

• Growing regulatory support for bio-based chemicals and sustainable materials

Get Full Report Here: 1,5-pentanediamine (Cadaverine) Market – View in Detailed Research Report

The companies listed above are not only supplying a critical biochemical intermediate—they’re driving the sustainable transformation of the chemical industry.