The Global Feed Nucleotides Market was valued at USD 385.7 Million in 2024 and is projected to reach USD 576.2 Million by 2029, growing at a Compound Annual Growth Rate (CAGR) of 8.2% during the forecast period (2024–2029). This robust growth is being propelled by the escalating global demand for animal protein, heightened focus on animal health and welfare, and the increasing adoption of nucleotide-based supplements in aquaculture and livestock feed to enhance immune response and growth performance.

As the animal nutrition industry pivots toward sustainable and health-oriented feeding practices, the focus intensifies on the key ingredient suppliers driving scientific innovation, product efficacy, and regulatory compliance. In this analysis, we profile the Top 10 Companies in the Feed Nucleotides Industry—a blend of global chemical giants, specialized bioscience firms, and animal nutrition leaders shaping the future of livestock and aquaculture health.

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🔟 1. Adisseo France SAS

Headquarters: Commentry, France
Key Offering: Rovimix® Nucleotides, Specialty Feed Additives

Adisseo is a global leader in animal nutrition, offering a comprehensive portfolio of feed additives, including its specialized Rovimix® nucleotides. The company invests heavily in research to develop solutions that improve animal gut health, immune function, and overall productivity, catering to poultry, swine, and aquaculture sectors worldwide.

Research & Development Focus:

• Advanced research in microbiome modulation

• Development of precision nutrition solutions

• Commitment to sustainable animal production

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9️⃣ 2. Ajinomoto Co., Inc.

Headquarters: Tokyo, Japan
Key Offering: Nucleotide-based feed supplements, AJI-NUC™

Ajinomoto, a world-renowned amino acid producer, has a significant presence in the feed nucleotides segment. Leveraging its expertise in fermentation technology, the company produces high-purity nucleotides that are essential for optimizing animal growth rates and strengthening immune systems, particularly in stress-prone farming conditions.

Research & Development Focus:

• Proprietary fermentation processes for nucleotide production

• Strategic focus on animal health and sustainable food solutions

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8️⃣ 3. Leiber GmbH

Headquarters: Bramsche, Germany
Key Offering: Brewers’ Yeast extracts rich in Nucleotides, Beta-G

Leiber GmbH specializes in the production of high-value yeast-based products derived from brewing processes. Their yeast extracts are a natural and rich source of nucleotides, beta-glucans, and other bioactive compounds, making them a preferred choice for functional feed ingredients that support animal immunity and digestive health.

Research & Development Focus:

• Specialization in bioactive yeast fractions

• Focus on natural and sustainable feed ingredients

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7️⃣ 4. Lesaffre Group

Headquarters: Marcq-en-Barœul, France
Key Offering: Nucleotide-rich yeast products, Actisaf® & Safmannan®

As a global key player in yeast and fermentation, Lesaffre offers a range of feed solutions that naturally contain nucleotides. Their products are designed to enhance animal performance, improve feed efficiency, and support immune function, backed by extensive research in yeast microbiology and application.

Research & Development Focus:

• Yeast technology innovation for animal nutrition

• Global application support and technical services

Download FREE Sample Report: Feed Nucleotides Global Market – View in Detailed Research Report

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6️⃣ 5. ADM (Archer-Daniels-Midland Company)

Headquarters: Chicago, Illinois, USA
Key Offering: Comprehensive animal nutrition portfolio, including nucleotide precursors

ADM is a premier global agricultural processor and food ingredient provider, with a substantial animal nutrition division. The company incorporates nucleotide-rich ingredients and supportive nutrients into its feed formulations, supporting optimal animal health and productivity across livestock and aquaculture chains.

Research & Development Focus:

• Integrated animal nutrition and health research

• Development of tailored feed solutions for different species

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5️⃣ 6. BASF SE

Headquarters: Ludwigshafen, Germany
Key Offering: NutriSustain® (includes nucleotide-rich ingredients), Vitamins & Enzymes

BASF’s animal nutrition business provides scientifically advanced solutions that encompass vitamins, enzymes, and other performance-enhancing additives. Their focus on gut health and immunity includes the utilization and development of ingredients that support natural nucleotide availability and utilization in animals.

Research & Development Focus:

• Science-based solutions for animal well-being

• Commitment to sustainability in animal farming

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4️⃣ 7. Biovet JSC

Headquarters: Stara Zagora, Bulgaria
Key Offering: Alquernat® range, feed additives with immunostimulant properties

Biovet JSC is a specialized manufacturer of feed additives with a strong focus on products that boost the natural defenses of animals. Their offerings, which include nucleotide-containing ingredients, are designed to improve health status and reduce the need for antibiotics in animal production, aligning with global antibiotic reduction trends.

Research & Development Focus:

• Development of natural growth promoters and immunostimulants

• R&D in alternatives to antibiotic growth promoters

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3️⃣ 8. Cargill Incorporated

Headquarters: Minneapolis, Minnesota, USA
Key Offering: Provimi® animal nutrition solutions, specialized feed ingredients

Cargill’s extensive animal nutrition business, Provimi, provides customized feeding programs that often incorporate nucleotide-rich ingredients to support animal health, especially during critical growth phases and periods of stress. Their global reach ensures these advanced solutions are available to farmers worldwide.

Research & Development Focus:

• Precision nutrition and customized feeding strategies

• Investment in R&D for sustainable animal protein production

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2️⃣ 9. DSM-Firmenich

Headquarters: Kaiseraugst, Switzerland
Key Offering: Nutritional solutions for gut health and immunity

Following the merger, DSM-Firmenich is a powerhouse in health, nutrition, and bioscience. The company’s animal nutrition and health division develops innovative solutions that support robust immune systems in livestock, which includes research and application of nucleotides and other key nutrients.

Research & Development Focus:

• Leading innovation in animal health and sustainability

• We Make It Possible strategy focused on sustainable agriculture

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1️⃣ 10. Nutreco N.V. / Trouw Nutrition

Headquarters: Amersfoort, Netherlands
Key Offering: Comprehensive feed specialties, gut health solutions

As part of the SHV Holdings, Nutreco and its subsidiary Trouw Nutrition are global leaders in animal nutrition. Their research-driven approach includes developing feed formulations that enhance innate immunity and overall animal resilience, utilizing a deep understanding of nutritional components like nucleotides.

Research & Development Focus:

• Extensive R&D in life-start and health-promoting feed solutions

• Global network of research centers and expertise

Get Full Report Here: Feed Nucleotides Global Market – View in Detailed Research Report

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🌍 Outlook: The Future of Feed Nucleotides Is Precision and Performance

The feed nucleotides market is at a pivotal point, transitioning from a niche supplement to a mainstream functional ingredient. While awareness of their benefits is growing, the industry is investing in advanced research to better understand mode-of-action, optimal dosage, and synergistic effects with other feed additives, paving the way for precision animal nutrition.

📈 Key Trends Shaping the Market:

• Rising demand for antibiotic-free animal production, driving the need for immune-supporting alternatives like nucleotides.

• Expansion of intensive aquaculture, where nucleotides are critical for larval development and disease resistance in fish and shrimp.

• Increasing scientific validation of nucleotides’ role in gut health maturation and vaccine response efficacy.

• Strategic mergers and R&D investments by key players to expand product portfolios and geographic reach.

Get Full Report Here: Feed Nucleotides Global Market – View in Detailed Research Report

The companies profiled above are not only supplying critical ingredients—they are advancing the science of animal nutrition and enabling a more sustainable and healthy global food supply.