The Global Human Serum Market was valued at USD 1.87 Billion in 2024 and is projected to reach USD 2.72 Billion by 2030, growing at a Compound Annual Growth Rate (CAGR) of 6.2% during the forecast period (2024–2030). This robust growth is primarily fueled by the expanding biopharmaceutical and cell culture sectors, rising demand for advanced vaccine production, and the increasing adoption of human serum in stem cell research and regenerative medicine.

As the life sciences industry pivots towards more complex biologics and personalized therapies, the reliability and quality of cell culture media components have become paramount. Human serum, a critical growth supplement, is at the heart of this revolution. In this blog, we profile the Top 10 Companies in the Human Serum Industry—a group of specialized suppliers, biotech giants, and quality assurance leaders shaping the standards for biologics manufacturing worldwide.

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🔟 1. Thermo Fisher Scientific Inc.

Headquarters: Waltham, Massachusetts, USA
Key Offering: Gibco™ Characterized Fetal Bovine Serum (FBS) Alternatives, Human AB Serum, Specialty Sera

Thermo Fisher Scientific is a dominant global supplier of scientific reagents, including a comprehensive portfolio of human serum products. Through its Gibco brand, the company provides rigorously tested human serum for critical applications in cell therapy, vaccine development, and biomanufacturing, ensuring high levels of consistency and performance.

Quality & Innovation Initiatives:

• Advanced characterization and viral testing protocols for superior batch-to-batch consistency.

• Investment in serum-free and xeno-free media alternatives to support regulatory compliance.

• Global supply chain logistics to ensure reliable delivery to research and production facilities.

Download FREE Sample Report: Global Human Serum Market – View in Detailed Research Report

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9️⃣ 2. Merck KGaA (MilliporeSigma)

Headquarters: Darmstadt, Germany
Key Offering: Human Serum, Type AB, Pooled Human Serum, SeraSure® Quality Control Kits

Merck KGaA, operating as MilliporeSigma in the life science business, is a key player in the production and distribution of high-quality human serum. The company is renowned for its stringent quality control measures, including the SeraSure® portfolio that helps researchers verify serum quality, making it a trusted partner for pharmaceutical and academic institutions.

Quality & Innovation Initiatives:

• Implementation of comprehensive viral and mycoplasma testing for enhanced safety.

• Development of traceable and documented sera for regulated environments (GMP/GLP).

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8️⃣ 3. Sigma-Aldrich (Part of Merck KGaA)

Headquarters: St. Louis, Missouri, USA
Key Offering: Human Serum, Pooled Human AB Serum, Iron-Supplemented Calf Bovine Serum

As a cornerstone of the Merck Group, Sigma-Aldrich provides a wide array of biological materials, including extensively characterized human serum. The company’s products are essential for basic research, drug discovery, and toxicity testing, supported by detailed certificates of analysis.

Quality & Innovation Initiatives:

• Rigorous donor screening and collection under standardized protocols.

• Focus on expanding product lines to support the growing cell and gene therapy market.

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7️⃣ 4. Biological Industries

Headquarters: Kibbutz Beit Haemek, Israel
Key Offering: Premium Grade Human Serum, Stem Cell Culture Media, Xeno-Free Supplements

Biological Industries specializes in cell culture solutions, with a strong focus on human-derived products for stem cell research and regenerative medicine. Their human serum is processed to maintain the highest biological activity, making it ideal for demanding applications like mesenchymal stem cell expansion.

Quality & Innovation Initiatives:

• Pioneering work in xeno-free and defined culture systems.

• Tailored serum formulations for specific cell types and research applications.

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6️⃣ 5. GE Healthcare (Now Cytiva)

Headquarters: Chicago, Illinois, USA
Key Offering: HyClone™ Characterized Fetal Bovine Serum, Human Platelet Lysate, Cell Culture Media

Cytiva, formerly part of GE Healthcare Life Sciences, is a leading provider of technologies and services for biomanufacturing. Its HyClone product line includes high-quality human serum alternatives and supplements designed to optimize cell growth in bioproduction processes, from clinical-scale to large-scale manufacturing.

Quality & Innovation Initiatives:

• Emphasis on scalable and consistent raw materials for bioprocessing.

• Development of human platelet lysate as a superior alternative to FBS in cell therapy.

Download FREE Sample Report: Global Human Serum Market – View in Detailed Research Report

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5️⃣ 6. Lonza Group Ltd.

Headquarters: Basel, Switzerland
Key Offering: Human-derived Supplements, Custom Media Formulations, Bioscience Solutions

Lonza is a global leader in life sciences, providing essential ingredients for the biotechnology and pharmaceutical industries. The company offers high-grade human serum and specialized supplements that are critical for the culture of primary cells and the production of advanced therapeutic medicinal products (ATMPs).

Quality & Innovation Initiatives:

• Integration of serum products with comprehensive cell culture systems and services.

• Focus on supporting the entire workflow from research to commercial-scale GMP manufacturing.

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4️⃣ 7. Innovative Research, Inc.

Headquarters: Novi, Michigan, USA
Key Offering: Pooled Human Plasma, Human Serum, Specialty Plasma Products

Innovative Research is a specialized supplier of human and animal plasma, serum, and biological materials. The company is known for providing a wide variety of human serum types, including defined donor pools, which are vital for assay development, diagnostics, and research requiring high levels of reproducibility.

Quality & Innovation Initiatives:

• Extensive donor qualification and product customization capabilities.

• Commitment to supplying materials for quality control and standardization in the diagnostic industry.

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3️⃣ 8. Gemini Bio-Products

Headquarters: West Sacramento, California, USA
Key Offering: Premium Fetal Bovine Serum, Human AB Serum, Cell Culture Supplements

Gemini Bio-Products is a trusted manufacturer and distributor of serum and cell culture reagents. While known for its FBS, the company also supplies high-quality human serum, adhering to strict collection and processing standards to ensure it meets the needs of sensitive biomedical research.

Quality & Innovation Initiatives:

• Stringent sourcing from FDA-licensed collection centers in the United States.

• Focus on customer service and providing tailored solutions for specific research requirements.

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2️⃣ 9. SeraCare Life Sciences (Part of LGC)

Headquarters: Milford, Massachusetts, USA
Key Offering: AccuSet™ Plasma and Serum Controls, Human Serology Panels, Custom Biologics

Now part of the LGC Group, SeraCare Life Sciences is a leading provider of quality control tools and biological materials for the diagnostics industry. The company’s expertise lies in producing highly characterized human serum and plasma used for calibrating and validating diagnostic assays, including for infectious diseases and oncology.

Quality & Innovation Initiatives:

• Specialization in creating commutable reference materials that behave like patient samples.

• Development of seroconversion panels and disease-state sera for diagnostic assay development.

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1️⃣ 10. Atlanta Biologicals (R&D Systems, a Bio-Techne brand)

Headquarters: Minneapolis, Minnesota, USA
Key Offering: Premium Sera, Cell Culture Reagents, Growth Factors

As part of Bio-Techne’s R&D Systems portfolio, Atlanta Biologicals is a key supplier of high-purity biological products, including human serum. The company’s products are designed to support cell-based research and bioproduction, with a strong emphasis on quality, consistency, and technical support for the scientific community.

Quality & Innovation Initiatives:

• Integration with a broad portfolio of proteins, antibodies, and assays for complete research solutions.

• Commitment to innovation in culture media formulations for advanced cell models like 3D cultures and organoids.

Get Full Report Here: Global Human Serum Market – View in Detailed Research Report

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🔬 Outlook: The Future of Human Serum is Defined and Regulated

The human serum market is undergoing a significant transformation. While traditional pooled and single-donor sera remain essential workhorses, the industry is rapidly advancing towards defined, xeno-free, and chemically defined alternatives to meet stringent regulatory requirements and enhance reproducibility in sensitive applications like cell and gene therapy.

📈 Key Trends Shaping the Market:

• Rising adoption of Human Platelet Lysate (HPL) as a superior, ethically sourced alternative to Fetal Bovine Serum in clinical applications.

• Increasing regulatory scrutiny driving demand for thoroughly characterized and traceable serum batches with extensive documentation.

• Growth in personalized medicine fueling the need for autologous serum and patient-specific culture conditions.

• Technological advancements in serum production, including pathogen inactivation methods and advanced filtration techniques.

Get Full Report Here: Global Human Serum Market – View in Detailed Research Report

The companies listed above are not merely suppliers of biological materials—they are enablers of groundbreaking medical discoveries and the next generation of biotherapeutics.