The Global N,N`-Carbonyldiimidazole (CDI) Market was valued at USD 182.5 Million in 2023 and is projected to reach USD 265.8 Million by 2028, growing at a Compound Annual Growth Rate (CAGR) of 7.8% during the forecast period (2023–2028). This robust growth is fueled by escalating demand from the pharmaceutical sector for peptide synthesis and the expanding need for high-purity agrochemical intermediates, particularly in emerging economies.

As the fine chemicals industry advances toward more efficient and safer coupling reagents, the focus intensifies on the key manufacturers who are driving innovation, ensuring supply chain stability, and expanding production capacities. In this analysis, we profile the Top 10 Companies in the N,N`-Carbonyldiimidazole (CDI) Industry—a combination of global chemical giants and specialized producers shaping the future of this critical reagent.

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🔟 1. Lanxess

Headquarters: Cologne, Germany
Key Offering: High-Purity CDI (Purity 99%)

Lanxess is a leading global specialty chemicals company with a strong portfolio that includes high-value intermediates like CDI. Its production facilities adhere to stringent quality standards, serving major pharmaceutical and agrochemical customers worldwide. The company leverages its extensive R&D capabilities to optimize CDI synthesis for improved yield and sustainability.

Innovation and Capacity Initiatives:

• Investment in green chemistry pathways for CDI production
• Strategic focus on high-purity grades for regulated markets
• Global supply chain optimization to ensure consistent delivery

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Global and Regional N,N`-Carbonyldiimidazole (CDI) Industry Status and Prospects Professional Market – View in Detailed Research Report

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9️⃣ 2. Quzhou Ruilijie Chemical Industry

Headquarters: Quzhou, Zhejiang, China
Key Offering: CDI (Purity 98%, 99%)

Quzhou Ruilijie Chemical is a major Chinese producer of CDI, with significant manufacturing capacity dedicated to serving both domestic and international markets. The company has established itself as a reliable supplier for cost-sensitive applications while maintaining competitive quality standards.

Innovation and Capacity Initiatives:

• Continuous process improvements for cost efficiency
• Expansion of production capacity to meet growing Asian demand
• Development of tailored CDI solutions for specific customer applications

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8️⃣ 3. Aolisen Chemical Company

Headquarters: Shanghai, China
Key Offering: Pharmaceutical and Industrial Grade CDI

Aolisen Chemical specializes in fine chemicals and pharmaceutical intermediates, with CDI being a core product in its portfolio. The company serves a diverse client base, from large pharmaceutical corporations to research institutions, emphasizing technical support and custom synthesis services.

Innovation and Capacity Initiatives:

• Strong R&D focus on impurity profiling and control
• Collaborations with academic institutions for process innovation
• Implementation of quality-by-design (QbD) principles in manufacturing

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Global and Regional N,N`-Carbonyldiimidazole (CDI) Industry Status and Prospects Professional Market – View in Detailed Research Report

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7️⃣ 4. Zhejiang Bulk Chemical

Headquarters: Taizhou, Zhejiang, China
Key Offering: CDI, Imidazole and Derivatives

Zhejiang Bulk Chemical benefits from vertical integration, producing CDI from base imidazole, which provides cost and supply chain advantages. The company is a significant exporter, particularly to markets in Southeast Asia and Europe, and has been scaling its operations to capitalize on the CDI market growth.

Innovation and Capacity Initiatives:

• Backward integration securing raw material supply
• Capacity expansion projects aligned with market demand forecasts
• Focus on environmental, health, and safety (EHS) compliance

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6️⃣ 5. Atul Ltd.

Headquarters: Valsad, Gujarat, India
Key Offering: CDI, Diversified Chemical Intermediates

Atul Ltd. is one of India’s leading chemical companies with a diverse product portfolio that includes CDI. Its strong position in the Indian market and established export channels make it a key player in the Asian region. The company’s integrated manufacturing complex allows for efficient production and cost management.

Innovation and Capacity Initiatives:

• Investment in R&D for sustainable manufacturing processes
• Expansion of fine chemicals division, including CDI capacity
• Strategic focus on the pharmaceutical and agrochemical verticals

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5️⃣ 6. Hangzhou Yunuo Chemical

Headquarters: Hangzhou, Zhejiang, China
Key Offering: High-Purity CDI for Pharmaceutical Applications

Hangzhou Yunuo Chemical specializes in high-purity chemical intermediates, with CDI being a flagship product. The company has built a reputation for quality and reliability, particularly in serving the stringent requirements of the pharmaceutical industry for peptide synthesis and other critical applications.

Innovation and Capacity Initiatives:

• Specialization in ultra-high purity (≥99.5%) CDI grades
• Implementation of advanced analytical techniques for quality control
• Customer-centric approach with tailored packaging and logistics

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4️⃣ 7. Changzhou Welton Chemical

Headquarters: Changzhou, Jiangsu, China
Key Offering: CDI, Custom Synthesis Services

Changzhou Welton Chemical is a specialist manufacturer of pharmaceutical intermediates and fine chemicals. The company’s expertise in CDI production is complemented by its ability to provide custom synthesis and contract manufacturing services, offering flexibility to its customers.

Innovation and Capacity Initiatives:

• Development of proprietary synthesis routes for improved efficiency
• Focus on scaling up laboratory processes to commercial production
• Strong technical service and application support team

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Global and Regional N,N`-Carbonyldiimidazole (CDI) Industry Status and Prospects Professional Market – View in Detailed Research Report

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3️⃣ 8. Changzhou Zhongkai Chemical

Headquarters: Changzhou, Jiangsu, China
Key Offering: CDI, Imidazole-based Fine Chemicals

Changzhou Zhongkai Chemical has established a strong presence in the CDI market through consistent quality and competitive pricing. The company’s strategic location in the Yangtze River Delta chemical industry cluster provides logistical advantages for both domestic distribution and international exports.

Innovation and Capacity Initiatives:

• Continuous process optimization to reduce production costs
• Expansion into derivative products based on the CDI platform
• Investment in environmental protection and waste treatment facilities

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2️⃣ 9. Hangzhou FST Pharmaceutical

Headquarters: Hangzhou, Zhejiang, China
Key Offering: Pharmaceutical Grade CDI, API Intermediates

Hangzhou FST Pharmaceutical focuses on intermediates for active pharmaceutical ingredients (APIs), positioning CDI as a critical reagent in its product lineup. The company’s deep understanding of pharmaceutical industry requirements ensures its CDI meets the highest standards for impurity profiles and documentation.

Innovation and Capacity Initiatives:

• cGMP compliant manufacturing facilities
• Strong quality management systems aligned with regulatory expectations
• Strategic partnerships with global pharmaceutical companies

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1️⃣ 10. Jiangxi Jinkai Chemical

Headquarters: Ji’an, Jiangxi, China
Key Offering: CDI, Pesticide Intermediates

Jiangxi Jinkai Chemical has carved a niche as a supplier to the agrochemical industry, where CDI is used in the synthesis of various herbicides and insecticides. The company’s focus on this segment allows it to tailor its product characteristics and technical support to the specific needs of pesticide manufacturers.

Innovation and Capacity Initiatives:

• Specialization in cost-effective CDI for agrochemical applications
• Development of application knowledge for pesticide synthesis
• Robust supply chain management for consistent raw material sourcing

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Global and Regional N,N`-Carbonyldiimidazole (CDI) Industry Status and Prospects Professional Market – View in Detailed Research Report

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🧪 Outlook: The Future of CDI is Tied to Pharmaceutical and Sustainable Chemistry Advances

The N,N’-Carbonyldiimidazole market is experiencing a significant transformation. While traditional applications continue to drive volume, the industry is increasingly focused on high-purity specifications, green chemistry principles, and supply chain resilience to support the evolving needs of the pharmaceutical and agrochemical sectors.

📈 Key Trends Shaping the Market:

• Growing adoption of CDI in peptide synthesis for biopharmaceuticals
• Increasing regulatory scrutiny driving demand for high-purity, well-characterized CDI
• Geographic shift in production capacity towards Asia, particularly China
• R&D focused on improving the sustainability profile of CDI manufacturing processes

Get Full Report Here:
Global and Regional N,N`-Carbonyldiimidazole (CDI) Industry Status and Prospects Professional Market – View in Detailed Research Report

The companies profiled above are not only supplying a critical chemical reagent—they are enabling innovation in life-saving pharmaceuticals and advanced crop protection solutions worldwide.