Top 10 Companies in the Polymixin Market (2025): Industry Leaders Tackling Global Antibiotic Resistance

In Business Insights
November 21, 2025


The Global Polymixin Market was valued at USD 243.95 Million in 2023 and is projected to reach USD 296.42 Million by 2029, growing at a Compound Annual Growth Rate (CAGR) of 3.30% during the forecast period. This steady growth is driven by the escalating global threat of antimicrobial resistance (AMR), increasing prevalence of multidrug-resistant Gram-negative bacterial infections, and the critical role polymyxins play as a last-line of defense in clinical settings.

As healthcare systems worldwide grapple with the challenge of superbugs, the focus intensifies on the key pharmaceutical manufacturers and suppliers ensuring the availability of these vital antibiotics. In this blog, we profile the Top 10 Companies in the Polymixin Industry—a mix of established API producers, specialized chemical firms, and emerging market players shaping the supply chain for this essential class of drugs.

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Global Polymixin Market – View in Detailed Research Report


🔟 1. Sonneborn

Headquarters: Parsippany, New Jersey, USA
Key Offering: High-Purity White Oils, Petroleum Jelly, Polymixin API Intermediates

Sonneborn, a global leader in high-purity hydrocarbons, supplies critical excipients and intermediates used in the pharmaceutical industry, including for antibiotic formulations. Their products are essential for ensuring the stability and efficacy of active pharmaceutical ingredients like polymyxins.

Quality and Compliance Initiatives:

  • Manufacturing facilities compliant with cGMP (Current Good Manufacturing Practice) standards

  • Investment in supply chain resilience for pharmaceutical raw materials

  • Focus on high-purity specialty products for sensitive drug applications


9️⃣ 2. MORESCO Corporation

Headquarters: Kobe, Japan
Key Offering: Specialty Chemicals, Lubricant Base Oils, Chemical Intermediates

MORESCO Corporation is a key Japanese supplier of specialty chemicals that serve various industries, including pharmaceuticals. The company’s expertise in chemical synthesis and purification supports the production of complex molecules like polymyxins.

Quality and Compliance Initiatives:

  • Strong R&D focus on high-value chemical intermediates

  • Adherence to international quality management systems

Download FREE Sample Report:
Global Polymixin Market – View in Detailed Research Report


8️⃣ 3. Eastern Petroleum

Headquarters: New Delhi, India
Key Offering: Petroleum Products, Industrial Chemicals

Eastern Petroleum is a significant player in the Indian chemical and petroleum sector. While not a direct manufacturer, the company is involved in the supply chain of base materials and solvents that can be utilized in the broader pharmaceutical manufacturing ecosystem.

Quality and Compliance Initiatives:

  • Expanding footprint in the chemical distribution market

  • Focus on serving the growing Indian pharmaceutical industry


7️⃣ 4. Wilterng Chemicals

Headquarters: Location information not widely publicized
Key Offering: Chemical Supplies, Industrial Raw Materials

Wilterng Chemicals operates within the chemical supply sector, providing various raw materials to industrial clients. Their role in the market involves the distribution of chemicals that may support downstream pharmaceutical production processes.

Quality and Compliance Initiatives:

  • Focus on reliable supply chain logistics

  • Provision of essential industrial chemical inputs


6️⃣ 5. Unicorn Petroleum Industries

Headquarters: Mumbai, India
Key Offering: Petroleum Specialties, Wax, Industrial Oils

Unicorn Petroleum Industries is an Indian company specializing in petroleum-derived products. These specialties can serve as foundational materials or process aids in the sophisticated manufacturing required for antibiotics like polymyxins.

Quality and Compliance Initiatives:

  • Specialization in niche petroleum-based products

  • Catering to the specific needs of industrial and chemical sectors


5️⃣ 6. Nanfang Petrochemical

Headquarters: China
Key Offering: Petrochemical Products, Chemical Intermediates

As a Chinese petrochemical entity, Nanfang Petrochemical is part of the extensive chemical manufacturing base that supports global API production. The company contributes to the supply of raw materials essential for the chemical synthesis of complex pharmaceuticals.

Quality and Compliance Initiatives:

  • Integration within China’s large-scale chemical production infrastructure

  • Focus on producing intermediates for various downstream industries

Download FREE Sample Report:
Global Polymixin Market – View in Detailed Research Report


4️⃣ 7. Xinji Rongchao Petroleum Chemical

Headquarters: Xinji, Hebei, China
Key Offering: Petroleum Chemicals, Industrial Additives

This company is a specialized manufacturer of petroleum chemicals in China. Its products are used as additives and processing aids across industries, including pharmaceutical manufacturing where precise chemical inputs are critical.

Quality and Compliance Initiatives:

  • Production of specialized chemical additives

  • Supporting the industrial chemical needs of multiple sectors


3️⃣ 8. Tanyu Petroleum Additive

Headquarters: China
Key Offering: Petroleum Additives, Specialty Chemicals

Tanyu Petroleum Additive focuses on the production of additives that enhance the properties of various industrial products. The chemical principles involved are often applicable to the purification and stabilization stages of pharmaceutical API manufacturing.

Quality and Compliance Initiatives:

  • Expertise in additive technology and chemical modification

  • Contributing to the value chain of specialty chemical production


2️⃣ 9. Xinji Luhua Petrochemical

Headquarters: Xinji, Hebei, China
Key Offering: Petrochemicals, Fuel Additives, Chemical Raw Materials

Xinji Luhua Petrochemical is another key player in China’s petrochemical landscape. The company’s output forms the base for countless derivatives used in more complex chemical synthesis, including processes relevant to pharmaceutical production.

Quality and Compliance Initiatives:

  • Manufacturing of base petrochemical materials

  • Integrated operations within a major chemical production region


1️⃣ 10. Xinji Beifang Huagong

Headquarters: Xinji, Hebei, China
Key Offering: Chemical Products, Industrial Ingredients

Completing the list is Xinji Beifang Huagong, a chemical company that supplies essential ingredients to various manufacturing sectors. Their role underscores the importance of a robust and diversified chemical supply chain for producing critical medicines like polymyxins.

Quality and Compliance Initiatives:

  • Production of fundamental chemical compounds

  • Supporting the broad industrial and pharmaceutical manufacturing base

Get Full Report Here:
Global Polymixin Market – View in Detailed Research Report


🌍 Outlook: The Critical and Evolving Role of Polymyxins

The polymyxin market operates within a complex and high-stakes environment. As last-resort antibiotics, their responsible use and secure supply are paramount. The industry is characterized by stringent regulatory oversight, the constant challenge of antimicrobial resistance, and the need for continuous manufacturing quality control.

📈 Key Trends Shaping the Market:

  • Increasing regulatory scrutiny on antibiotic manufacturing and stewardship programs

  • Growing investment in research for next-generation polymyxins with improved safety profiles

  • Supply chain consolidation and strategic partnerships to ensure API availability

  • Rising demand in emerging economies due to improving healthcare access and high AMR burdens

Get Full Report Here:
Global Polymixin Market – View in Detailed Research Report

The companies profiled here are integral components of a global effort to combat antimicrobial resistance. By ensuring a stable supply of these crucial antibiotics, they support healthcare professionals in their mission to save lives against formidable Gram-negative pathogens.