The Global Methylidenesuccinic Acid Market was valued at USD 215.8 Million in 2023 and is projected to reach USD 332.5 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 6.1% during the forecast period (2024–2030). This growth is primarily driven by the escalating demand for bio-based products, the expansion of applications in polymers and synthetic latex, and the chemical industry’s strategic shift towards sustainable raw materials.

As the global economy increasingly prioritizes green chemistry and renewable resources, the focus intensifies on the key producers who are advancing fermentation technologies and expanding production capacities. In this blog, we profile the Top 10 Companies in the Methylidenesuccinic Acid Industry—a group of specialized biochemical firms and chemical manufacturers shaping the supply chain for this versatile organic acid.

---

🔟 1. Kehai Biochemistry

Headquarters: Jinan, Shandong, China
Key Offering: High-Purity Methylidenesuccinic Acid (Itaconic Acid)

Kehai Biochemistry is a leading global producer of itaconic acid, utilizing advanced fermentation processes to manufacture high-quality methylidenesuccinic acid. The company serves a diverse range of industries, including plastics, synthetic resins, and lubricant additives, with a strong focus on research and development to enhance yield and purity.

Production and Innovation Initiatives:

• Continuous investment in bio-fermentation capacity expansion

• Development of high-purity grades for specialized applications

• Commitment to achieving sustainable production with reduced environmental footprint

Download FREE Sample Report: Methylidenesuccinic Acid Market – View in Detailed Research Report

---

9️⃣ 2. Guoguang Biochemistry

Headquarters: Zhejiang, China
Key Offering: Methylidenesuccinic Acid, Itaconic Acid Derivatives

Guoguang Biochemistry operates significant production facilities for itaconic acid and has established itself as a key supplier in the Asian market. The company leverages its biochemical expertise to cater to the growing demand from the paint, coating, and plasticizer industries.

Production and Innovation Initiatives:

• Strategic focus on downstream derivative development

• Optimization of fermentation technology for cost-effective production

---

8️⃣ 3. Huaming Biochemistry

Headquarters: Shandong, China
Key Offering: Industrial and Pharmaceutical Grade Itaconic Acid

Huaming Biochemistry is a prominent manufacturer with a robust portfolio of biochemical products, including methylidenesuccinic acid. The company supplies both standard industrial grades and higher-purity variants suitable for more sensitive applications, demonstrating versatility in its market approach.

Production and Innovation Initiatives:

• Diversification into high-value application segments

• Strengthening of global distribution networks

---

7️⃣ 4. Alpha Chemika

Headquarters: Maharashtra, India
Key Offering: Methylidenesuccinic Acid, Specialty Chemicals

Alpha Chemika is a key chemical supplier and distributor, providing high-purity methylidenesuccinic acid to research institutions and industrial clients. The company plays a crucial role in the supply chain, ensuring the availability of this specialty chemical across various regions.

Production and Innovation Initiatives:

• Focus on serving the research and development sector

• Expansion of product portfolio to include related bio-based chemicals

---

6️⃣ 5. Zhongshun Science & Technology

Headquarters: Jiangsu, China
Key Offering: Itaconic Acid for Polymer Applications

Zhongshun Science & Technology is engaged in the production and technological development of itaconic acid, with a particular emphasis on serving the polymer and material science industries. The company invests in process innovation to improve the efficiency of its bioproduction lines.

Production and Innovation Initiatives:

• Development of application-specific itaconic acid formulations

• Collaborations with academic institutions for R&D

Download FREE Sample Report: Methylidenesuccinic Acid Market – View in Detailed Research Report

---

5️⃣ 6. Itaconix Corporation

Headquarters: Stratham, New Hampshire, USA
Key Offering: Specialty Polymers from Itaconic Acid

Itaconix PLC is a leader in developing and producing specialty polymers derived from itaconic acid. While not a primary producer of the acid itself, the company is a significant downstream consumer and innovator, creating high-value, bio-based alternatives to petroleum-based ingredients in consumer and industrial products.

Production and Innovation Initiatives:

• Pioneering bio-based polymers for detergents and personal care

• Focus on creating sustainable and biodegradable material solutions

---

4️⃣ 7. Jinan Huaming Biochemistry Co., Ltd.

Headquarters: Jinan, China
Key Offering: Bulk Methylidenesuccinic Acid

This specialized biochemical company is dedicated to the large-scale production of itaconic acid. It has built a reputation for reliability and consistent quality, supplying bulk quantities to major industrial consumers globally.

Production and Innovation Initiatives:

• Scale-up of fermentation-based production capabilities

• Implementation of stringent quality control systems

---

3️⃣ 8. Shandong Kaison Biochemical Co., Ltd.

Headquarters: Shandong, China
Key Offering: Itaconic Acid for Industrial Use

Shandong Kaison Biochemical is a significant manufacturer in the global itaconic acid market, with a strong production base in one of China’s major chemical industry hubs. The company supplies a wide range of industries, contributing to the bio-based economy.

Production and Innovation Initiatives:

• Continuous process optimization for enhanced productivity

• Exploration of new market applications for itaconic acid

---

2️⃣ 9. Chengdu Jinkai Biology Engineering Co., Ltd.

Headquarters: Sichuan, China
Key Offering: Bio-based Itaconic Acid

Chengdu Jinkai Biology Engineering specializes in microbial fermentation technologies for producing various bio-chemicals, including methylidenesuccinic acid. The company focuses on the technological aspects of production to maintain a competitive edge.

Production and Innovation Initiatives:

• Investment in advanced bioprocessing equipment

• Development of proprietary microbial strains for fermentation

---

1️⃣ 10. Ronas Chemicals Ind. Co., Ltd.

Headquarters: Shanghai, China
Key Offering: Chemical Intermediates including Itaconic Acid

Ronas Chemicals is a supplier and distributor of a wide range of chemical intermediates, including methylidenesuccinic acid. The company plays a vital role in the global chemical supply chain, connecting producers with end-users in various specialty sectors.

Production and Innovation Initiatives:

• Maintenance of a diversified chemical portfolio

• Strong logistical network for global distribution

Get Full Report Here: Methylidenesuccinic Acid Market – View in Detailed Research Report

---

🌍 Outlook: The Future of Methylidenesuccinic Acid is Bio-Based and Versatile

The methylidenesuccinic acid market is experiencing a significant transformation. Driven by the global push for sustainability, the industry is shifting from traditional chemical synthesis to fermentation-based production, which offers a more environmentally friendly and scalable pathway.

📈 Key Trends Shaping the Market:

• Accelerated adoption of bio-fermentation processes over chemical synthesis

• Growing demand from the plastics and polymers sector for sustainable monomers

• Increasing R&D investment for novel applications in medicine and advanced materials

• Expansion of production capacities, particularly in the Asia-Pacific region

Get Full Report Here: Methylidenesuccinic Acid Market – View in Detailed Research Report

The companies listed above are not only supplying a critical chemical intermediate—they are enabling the transition to a more sustainable chemical industry.