The Global Folic Acid (D-Isomer) Market was valued at USD 1.32 Billion in 2024 and is projected to reach USD 1.85 Billion by 2030, growing at a Compound Annual Growth Rate (CAGR) of 5.8% during the forecast period (2024–2030). This robust growth is primarily driven by rising awareness of neural tube defect prevention, increasing fortification mandates in food supplies globally, and the expanding demand for dietary supplements and animal nutrition.

As public health initiatives and consumer wellness trends converge, the critical role of folic acid in prenatal health, cardiovascular wellness, and livestock development is receiving unprecedented focus. This blog profiles the Top 10 Companies in the Folic Acid (D-Isomer) Industry—a group of global chemical giants and specialized manufacturers who are essential to the global supply chain for this vital nutrient.

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🔟 1. DSM

Headquarters: Heerlen, Netherlands
Key Offering: High-Purity Pharmaceutical and Food Grade Folic Acid

DSM is a world-leading producer of vitamins and nutritional ingredients, with a significant market share in folic acid. The company supplies high-purity folic acid to the pharmaceutical, infant formula, and dietary supplement industries, backed by extensive R&D and strict quality control.

Key Market Strengths:

• Leading position in high-value pharmaceutical-grade folic acid

• Strong focus on sustainable production processes

• Global supply chain supporting major food and pharma brands

Download FREE Sample Report: Global and United States Folic Acid (D-Isomer) Market – View in Detailed Research Report

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9️⃣ 2. BASF SE

Headquarters: Ludwigshafen, Germany
Key Offering: Broad portfolio including feed, food, and pharmaceutical grade folic acid

BASF’s Human Nutrition division is a key global supplier of folic acid, catering to diverse application needs. The company leverages its integrated chemical production expertise to ensure consistent quality and supply security for customers worldwide.

Key Market Strengths:

• Vertically integrated production from raw materials

• Extensive global distribution network

• Active participation in shaping global fortification standards

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8️⃣ 3. Xinfa Pharmaceutical Co., Ltd.

Headquarters: Shijiazhuang, Hebei, China
Key Offering: Cost-competitive folic acid for feed and food applications

Xinfa Pharmaceutical is one of China’s major producers of folic acid, playing a crucial role in the global supply chain. The company specializes in producing folic acid at scale, serving both domestic and international markets, particularly in the animal feed and staple food fortification sectors.

Key Market Strengths:

• Large-scale production capacity in a key manufacturing region

• Competitive pricing for bulk feed and food grade products

• Strategic focus on export markets in Asia and Africa

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7️⃣ 4. Niutang Chemical (Zhangjiagang) Co., Ltd.

Headquarters: Zhangjiagang, Jiangsu, China
Key Offering: Folic acid for pharmaceutical and high-grade food applications

Niutang is a significant producer of fine chemicals, including high-purity folic acid. The company has established a strong reputation for quality and reliability, supplying to pharmaceutical companies and premium supplement manufacturers globally.

Key Market Strengths:

• Focus on high-purity, pharmaceutical-grade folic acid

• Established quality management systems and regulatory compliance

• Strong technical support and customer service

Download FREE Sample Report: Global and United States Folic Acid (D-Isomer) Market – View in Detailed Research Report

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6️⃣ 5. Zhejiang Shengda Bio-pharm Co., Ltd.

Headquarters: Shaoxing, Zhejiang, China
Key Offering: Comprehensive range of folic acid grades

Zhejiang Shengda is a prominent Chinese manufacturer specializing in vitamins and amino acids. The company produces folic acid for various end-use sectors, leveraging its production efficiency to serve cost-sensitive markets without compromising on quality.

Key Market Strengths:

• Diversified product portfolio serving multiple industries

• Competitive manufacturing cost structure

• Growing export footprint in emerging economies

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5️⃣ 6. Changzhou Xinhong Pharmaceutical Chemical Co., Ltd.

Headquarters: Changzhou, Jiangsu, China
Key Offering: Pharmaceutical intermediates and folic acid

Changzhou Xinhong specializes in the production of pharmaceutical intermediates, including folic acid. The company’s expertise in chemical synthesis makes it a reliable supplier for pharmaceutical companies requiring high-purity ingredients for formulation.

Key Market Strengths:

• Specialization in pharmaceutical-grade ingredients

• Technical expertise in complex chemical synthesis

• Established relationships with global pharmaceutical clients

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4️⃣ 7. Jiheng Pharmaceutical Co., Ltd.

Headquarters: Shijiazhuang, Hebei, China
Key Offering: Folic acid primarily for the pharmaceutical and supplement industries

Jiheng Pharmaceutical is a specialized producer of pharmaceutical chemicals and vitamins. The company has built a strong position in the folic acid market by focusing on quality consistency and meeting the stringent requirements of health regulators in various countries.

Key Market Strengths:

• Focus on regulatory compliance for pharmaceutical applications

• Robust quality assurance processes

• Strategic location in a major pharmaceutical chemical hub

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3️⃣ 8. Changzhou Kangrui Chemical Co., Ltd.

Headquarters: Changzhou, Jiangsu, China
Key Offering: Folic acid for food fortification and animal nutrition

Changzhou Kangrui is an emerging player in the folic acid market, focusing on serving the growing demand from the food and feed industries. The company is investing in production technology to enhance its market presence and product quality.

Key Market Strengths:

• Growing production capacity to meet increasing demand

• Competitive positioning in the food and feed segments

• Investment in modern manufacturing technologies

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2️⃣ 9. Jiangxi Tianxin Pharmaceutical Co., Ltd.

Headquarters: Nanchang, Jiangxi, China
Key Offering: Folic acid with a focus on pharmaceutical applications

Jiangxi Tianxin is a pharmaceutical company that produces folic acid as part of its broader portfolio of active pharmaceutical ingredients (APIs). The company’s pharmaceutical background ensures a strong focus on purity and compliance with good manufacturing practices (GMP).

Key Market Strengths:

• Pharmaceutical company heritage ensuring high-quality standards

• Expertise in API manufacturing and regulation

• Strategic focus on value-added pharmaceutical grades

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1️⃣ 10. Other Key Regional Players

Headquarters: Various global locations
Key Offering: Folic acid for local and niche markets

Beyond the major global players, several regional and local manufacturers contribute significantly to the folic acid supply chain. These companies often serve specific geographic markets or specialized application niches, ensuring a diversified and resilient global supply.

Key Market Strengths:

• Ability to serve local market needs effectively

• Niche expertise in specific applications or regions

• Agility in responding to regional demand fluctuations

Get Full Report Here: Global and United States Folic Acid (D-Isomer) Market – View in Detailed Research Report

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🌍 Outlook: The Future of Folic Acid (D-Isomer) is Driven by Health and Fortification

The folic acid market is undergoing a significant transformation, moving beyond traditional supplement applications into broader public health and wellness initiatives. While pharmaceutical applications remain critical, the growth engine is increasingly powered by mandatory food fortification programs and the rising demand for optimized animal nutrition.

📈 Key Trends Shaping the Market:

• Expansion of government-led food fortification programs in developing economies

• Growing consumer awareness of folic acid’s role in preventing chronic diseases

• Increased demand for high-purity pharmaceutical-grade folic acid in advanced therapeutics

• Strategic expansions and capacity increases by key Chinese manufacturers

Get Full Report Here: Global and United States Folic Acid (D-Isomer) Market – View in Detailed Research Report

The companies profiled above are not only supplying a critical nutrient—they are enabling global public health initiatives and supporting the nutritional foundations of populations and livestock worldwide.