Top 10 Companies in the Squalene Market (2025): Key Players Driving the Natural Ingredient Industry

In Business Insights
November 20, 2025


The Global Squalene Market was valued at USD 112 Million in 2023 and is projected to reach USD 158.5 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 4.6% during the forecast period (2024–2030). This robust growth is primarily fueled by the rising consumer demand for natural and organic ingredients in cosmetics and personal care, alongside expanding applications in pharmaceuticals and nutraceuticals.

As the preference for plant-based and sustainably sourced ingredients reshapes consumer markets, the focus intensifies on the key suppliers who are pioneering ethical sourcing, advanced purification, and innovative production methods. This blog profiles the Top 10 Companies in the Squalene Market—a diverse group of biotechnology firms, marine oil specialists, and olive oil processors defining the future of this vital natural compound.


🔟 1. Seadragon Marine Oils Limited

Headquarters: Nelson, New Zealand
Key Offering: Shark Liver Oil-derived Squalene, Refined Marine Oils

Seadragon Marine Oils is a leading producer of high-purity, marine-derived squalene, specializing in oils sourced from deep-sea sharks. The company operates with a strong focus on sustainable and traceable sourcing practices, catering to the pharmaceutical and high-end cosmetic industries globally.

Sustainability Initiatives:

  • Commitment to Marine Stewardship Council (MSC) standards

  • Investment in by-product utilization to minimize waste

  • Active member of sustainable fisheries partnerships

Download FREE Sample Report: Squalene Market – View in Detailed Research Report


9️⃣ 2. Amyris, Inc.

Headquarters: Emeryville, California, USA
Key Offering: Bio-based Squalene (Neossance® Squalane)

Amyris is a pioneer in synthetic biology, producing 100% plant-derived squalane (the hydrogenated form of squalene) through the fermentation of sugarcane. Its Neossance® Squalane is a sustainable, consistent, and vegan alternative to animal-derived squalene, widely adopted by major cosmetic brands.

Sustainability Initiatives:

  • Renewable sugarcane-based production process

  • Carbon-negative manufacturing platform

  • Partnerships with global beauty and wellness companies


8️⃣ 3. Maruha Nichiro Corporation

Headquarters: Tokyo, Japan
Key Offering: Marine-based Squalene, Fish Oil Concentrates

Maruha Nichiro, one of Japan’s largest seafood companies, is a significant player in the squalene market, leveraging its extensive fisheries operations. The company produces high-grade squalene primarily from shark liver oil, supplying the pharmaceutical and cosmetic sectors.

Sustainability Initiatives:

  • Implementation of comprehensive traceability systems

  • Research into alternative, sustainable marine sources

  • Adherence to Japan’s stringent fisheries management laws


7️⃣ 4. Sophim

Headquarters: Peyruis, France
Key Offering: Phytosqualan® (Olive-derived Squalane)

Sophim is a European leader in producing vegetable-origin squalane from olive oil. Its flagship product, Phytosqualan®, is a fully hydrogenated and purified emollient prized in cosmetics for its stability, non-comedogenic properties, and natural origin.

Sustainability Initiatives:

  • Exclusive use of renewable vegetable raw materials

  • Eco-friendly extraction and hydrogenation processes

  • Focus on a transparent, “seed-to-skin” supply chain

Download FREE Sample Report: Squalene Market – View in Detailed Research Report


6️⃣ 5. Kishimoto Special Liver Oil Co., Ltd.

Headquarters: Tokyo, Japan
Key Offering: Squalene, Squalane, Shark Liver Oil extracts

With over a century of experience, Kishimoto is a specialist in processing fish liver oils, including high-purity squalene. The company serves a global clientele in the cosmetic, pharmaceutical, and health supplement industries, emphasizing product purity and quality control.

Sustainability Initiatives:

  • Long-standing commitment to responsible sourcing

  • Advanced refining technologies to maximize yield and purity

  • Compliance with international quality standards (ISO, GMP)


5️⃣ 6. Empresa Figueirense De Pesca, Lda

Headquarters: Figueira da Foz, Portugal
Key Offering: Shark Liver Oil Squalene

This Portuguese company is a key European supplier of squalene derived from shark liver oil. Empresa Figueirense De Pesca has built a reputation for reliability and quality, supplying bulk squalene to manufacturers across the continent.

Sustainability Initiatives:

  • Sourcing aligned with EU fisheries regulations

  • Investment in efficient processing to reduce environmental impact

  • Focus on by-product valorization from fishing operations


4️⃣ 7. Nucelis LLC

Headquarters: San Diego, California, USA
Key Offering: Sustainable, Fermentation-derived Squalene

Nucelis leverages advanced strain engineering and fermentation technologies to produce sustainable squalene. As a biotechnology innovator, the company focuses on creating high-value ingredients without relying on traditional animal or plant extraction methods.

Sustainability Initiatives:

  • Proprietary microbial fermentation platform

  • Elimination of supply chain dependencies on endangered species

  • Development of a scalable, consistent production process


3️⃣ 8. Arista Industries, Inc.

Headquarters: Wilton, Connecticut, USA
Key Offering: Squalene, Squalane (Animal and Vegetable Source)

Arista Industries is a well-established supplier of natural oils and lipids, offering both animal-derived and vegetable-derived squalene and squalane. The company provides tailored solutions to meet specific formulation requirements in cosmetics and health supplements.

Sustainability Initiatives:

  • Diversified sourcing to offer sustainable options

  • Strong focus on organic and natural product certifications

  • Commitment to transparent labeling and sourcing information


2️⃣ 9. EKIZ Olive Oil & Soap

Headquarters: Ayvalık, Turkey
Key Offering: Olive-derived Squalene

EKIZ is a major Turkish producer that utilizes its extensive olive oil operations to extract squalene. The company benefits from the rich olive-growing region of Ayvalık, providing a geographically strategic source of vegetable-based squalene for European and Asian markets.

Sustainability Initiatives:

  • Integration of squalene production within a circular olive economy

  • Utilization of by-products from olive oil production

  • Promotion of traditional and sustainable agricultural practices


1️⃣ 10. New Zealand Green Health Ltd.

Headquarters: Auckland, New Zealand
Key Offering: Olive Squalene, Dietary Supplements

New Zealand Green Health specializes in olive-derived squalene, marketing it for both cosmetic and dietary supplement applications. The company capitalizes on New Zealand’s reputation for purity and quality, targeting health-conscious consumers worldwide.

Sustainability Initiatives:

  • Emphasis on 100% plant-based, vegan products

  • Sourcing from sustainable olive groves

  • Development of eco-friendly packaging solutions

Get Full Report Here: Squalene Market – View in Detailed Research Report


🌍 Outlook: The Future of Squalene Is Sustainable and Plant-Based

The squalene market is undergoing a significant transformation. While shark liver oil historically dominated supply, increasing regulatory pressure and shifting consumer preferences are accelerating the transition toward plant-based and biosynthetic alternatives. The industry’s future hinges on innovation in biotechnology and the scalability of sustainable sourcing.

📈 Key Trends Shaping the Market:

  • Rapid growth of vegan and “clean beauty” movements driving demand for plant-derived squalane

  • Advancements in synthetic biology enabling cost-effective fermentation-based production

  • Stringent regulations on shark fishing promoting alternative sources

  • Expanding pharmaceutical applications in vaccine adjuvants and drug delivery systems

Get Full Report Here: Squalene Market – View in Detailed Research Report

The companies leading the squalene market are not just supplying a valuable ingredient—they are actively building a more sustainable and ethical future for the cosmetics, pharmaceutical, and nutraceutical industries.