The Global Injection Grade Sodium Hyaluronate Market was valued at USD 245.55 Million in 2023 and is projected to reach USD 327.19 Million by 2029, growing at a Compound Annual Growth Rate (CAGR) of 4.90% during the forecast period (2024–2029). This robust growth is propelled by the rising global demand for minimally invasive aesthetic procedures, the increasing prevalence of osteoarthritis, and significant advancements in biomedical applications such as tissue engineering and ophthalmic surgery.

As the healthcare and aesthetics industries increasingly rely on high-purity, biocompatible materials, the focus intensifies on the key manufacturers who ensure stringent quality control and drive innovation in biopolymer science. In this blog, we profile the Top 10 Companies in the Injection Grade Sodium Hyaluronate Industry—a group of established biotech firms and specialized manufacturers shaping the future of medical-grade hyaluronic acid.

Download FREE Sample Report:
Global Injection Grade Sodium Hyaluronate Market – View in Detailed Research Report

---

🔟 1. Bloomage Biotechnology Corporation Limited

Headquarters: Jinan, Shandong, China
Key Offering: High-purity Sodium Hyaluronate API and Finished Formulations

Bloomage Biotechnology is a global leader in hyaluronic acid production, with a significant market share in the injection-grade segment. The company operates state-of-the-art fermentation and purification facilities, supplying raw materials to major pharmaceutical and aesthetic companies worldwide. Their focus on R&D has led to a diverse portfolio of HA-based products for various medical applications.

Innovation and Market Position:

• World’s largest producer of hyaluronic acid by capacity

• Extensive portfolio covering pharmaceuticals, medical devices, and functional foods

• Strong vertical integration from raw material to finished product

---

9️⃣ 2. Lifecore Biomedical

Headquarters: Chaska, Minnesota, USA
Key Offering: USP-grade Sodium Hyaluronate, OVDs, and Contract Manufacturing

Lifecore Biomedical is a fully integrated contract development and manufacturing organization (CDMO) specializing in sterile, injectable formulations. The company is renowned for its expertise in fermentation-based hyaluronic acid, supplying critical components for ophthalmic viscosurgical devices (OVDs) and orthopedic injections with a strong emphasis on cGMP compliance.

Innovation and Market Position:

• Leading CDMO for complex, sterile injectable drug products

• Proprietary fermentation and purification technology platform

• Long-term supply agreements with global healthcare companies

---

8️⃣ 3. Contipro

Headquarters: Dolní Dobrouč, Czech Republic
Key Offering: Hyaluronic Acid of various molecular weights, Custom Derivatives

Contipro is a European leader in the research, development, and production of hyaluronic acid and its derivatives. The company distinguishes itself through advanced biotechnological production methods and a strong focus on innovative HA-based products for advanced medical and cosmetic applications, including patented cross-linked forms.

Innovation and Market Position:

• Specialization in high-value, differentiated HA derivatives

• Strong IP portfolio with numerous patents for HA technologies

• Focus on sustainable and animal-free production processes

---

7️⃣ 4. HTL Biotechnology

Headquarters: Javené, France
Key Offering: HYAJECT® and HYAFF® branded medical-grade HA

HTL Biotechnology is a French company with over 30 years of experience in developing and manufacturing hyaluronic acid-based biomaterials. The company’s products are used in a wide range of medical devices, including viscosupplementation products for orthopedics, dermal fillers, and advanced wound care solutions.

Innovation and Market Position:

• Pioneer in esterified hyaluronic acid (HYAFF® technology)

• Strategic supplier to the regenerative medicine industry

• Compliance with the highest international regulatory standards (FDA, EMA)

Download FREE Sample Report:
Global Injection Grade Sodium Hyaluronate Market – View in Detailed Research Report

---

6️⃣ 5. Haohai Biological

Headquarters: Taizhou, Jiangsu, China
Key Offering: Ophthalmic and Orthopedic HA-based Medical Devices

Haohai Biological is a leading Chinese company focused on the research, development, production, and sale of biomedical materials, primarily hyaluronic acid. The company has a strong presence in the domestic Chinese market and is expanding globally with its portfolio of single-injection and three-injection cycle orthopedic HA products and ophthalmic viscoelastic products.

Innovation and Market Position:

• Dominant player in the fast-growing Chinese medical aesthetics and orthopedic markets

• Integrated business model from raw material to branded finished products

• Continuous expansion of production capacity to meet rising demand

---

5️⃣ 6. Shandong Topscience Biotech Co., Ltd.

Headquarters: Jinan, Shandong, China
Key Offering: Pharmaceutical-Grade Sodium Hyaluronate API

Shandong Topscience Biotech is a major manufacturer of high-purity sodium hyaluronate, catering to the pharmaceutical and cosmetic industries. The company utilizes advanced microbial fermentation and purification technologies to produce HA that meets the stringent requirements of pharmacopoeias worldwide, serving a diverse global client base.

Innovation and Market Position:

• Significant production capacity for pharmaceutical-grade HA

• Focus on cost-effective manufacturing while maintaining high quality

• Established supplier to international distributors and formulators

---

4️⃣ 7. Kangcare Bioindustry Co.,Ltd

Headquarters: Xi’an, Shaanxi, China
Key Offering: Medical and Cosmetic Grade Hyaluronic Acid

Kangcare Bioindustry specializes in the research, production, and sales of hyaluronic acid and other biological products. The company has built a reputation for quality and reliability, supplying injection-grade sodium hyaluronate to manufacturers of dermal fillers and other medical devices, with a growing footprint in international markets.

Innovation and Market Position:

• Robust R&D capabilities focused on HA purification and characterization

• Strategic focus on the high-growth medical aesthetics sector

• Certifications including ISO 13485 for medical device quality management

---

3️⃣ 8. Altergon

Headquarters: Morra De Sanctis, Italy
Key Offering: IRAFIL® and IRATHIAL® branded medical HA

Altergon is an Italian company dedicated to the research and production of hyaluronic acid for pharmaceutical, medical device, and nutraceutical applications. The company’s strength lies in its proprietary production process that ensures high purity and specific molecular weight profiles, making it a trusted partner for specialized medical formulations.

Innovation and Market Position:

• Expertise in tailoring HA molecular weight for specific therapeutic indications

• Strong presence in the European pharmaceutical market

• Commitment to developing innovative HA-based drug delivery systems

---

2️⃣ 9. Huons

Headquarters: Seoul, South Korea
Key Offering: Finished Dermal Fillers and HA Raw Materials

Huons is a prominent South Korean pharmaceutical and biotech company with a significant stake in the global aesthetics market. While widely known for its branded dermal fillers, the company also possesses strong in-house capabilities for the production of high-quality injection-grade sodium hyaluronate, supplying both its own products and the broader market.

Innovation and Market Position:

• Vertically integrated from API manufacturing to commercial finished products

• Strong brand recognition in the Asian aesthetics market

• Active in R&D for next-generation HA-based biopharmaceuticals

---

1️⃣ 10. Shandong Awa Biopharm Co Ltd

Headquarters: Jinan, Shandong, China
Key Offering: High Purity Hyaluronic Acid Sodium Salt

Shandong Awa Biopharm is a specialized manufacturer of hyaluronic acid, focusing on producing a range of grades to meet diverse industry needs. The company has established itself as a reliable supplier of injection-grade material, adhering to strict quality control measures to ensure product safety and efficacy for critical medical applications.

Innovation and Market Position:

• Focus on scalable and efficient production processes

• Growing export business to North America and European markets

• Investment in capacity expansion to capitalize on market growth

Get Full Report Here:
Global Injection Grade Sodium Hyaluronate Market – View in Detailed Research Report

---

🔬 Outlook: The Future of Injection Grade Sodium Hyaluronate Is Precision and Personalization

The injection grade sodium hyaluronate market is undergoing a significant transformation. While traditional applications in osteoarthritis and dermal fillers continue to drive volume, the industry is investing heavily in advanced drug delivery systems, combination products, and personalized medicine approaches.

📈 Key Trends Shaping the Market:

• Rising adoption of long-lasting, cross-linked HA formulations for sustained therapeutic effect

• Expansion into novel therapeutic areas such as drug delivery for cancer therapeutics and regenerative medicine

• Increasing regulatory scrutiny and demand for higher purity standards and complex characterization data

• Strategic partnerships between raw material suppliers and drug/device developers to co-create innovative products

Get Full Report Here:
Global Injection Grade Sodium Hyaluronate Market – View in Detailed Research Report

The companies listed above are not only supplying a critical biomedical ingredient—they are enabling the next wave of minimally invasive therapies that improve patient outcomes across a spectrum of medical fields.