The Global 1,5-pentanediamine (Cadaverine) Market was valued at USD 26 Million in 2024 and is projected to reach USD 32 Million by 2032, growing at a Compound Annual Growth Rate (CAGR) of 3.1% during the forecast period (2024–2032). This steady growth is being driven by the expanding applications in bio-based polyamides, rising demand from the pharmaceutical sector, and technological advancements in sustainable production methods.
As the chemical industry pivots toward sustainable and bio-derived materials, the spotlight is on the key producers who are driving innovation, production efficiency, and specialized applications. In this blog, we profile the Top 10 Companies in the 1,5-pentanediamine (Cadaverine) Industry—a mix of biotechnology leaders, chemical giants, and specialty suppliers shaping the future of this biochemical intermediate.
🔟 1. Cathay Biotech Inc.
Headquarters: Shanghai, China
Key Offering: High-Purity 1,5-pentanediamine, Bio-based Polyamide Intermediates
Cathay Biotech is the undisputed global leader in the cadaverine market, commanding an estimated 90% market share. The company leverages its expertise in industrial biotechnology and vertical integration with lysine production to offer cost-competitive, high-quality 1,5-pentanediamine. Its products are essential for manufacturing bio-based nylon 5X, serving major polymer producers worldwide.
Innovation Initiatives:
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Proprietary microbial fermentation technology for high-yield production
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Continuous expansion of production capacity to meet growing bio-polymer demand
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Strategic partnerships with global chemical companies for application development
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1,5-pentanediamine (Cadaverine) Market – View in Detailed Research Report
9️⃣ 2. Ningxia Eppen Biotechnology Co., Ltd.
Headquarters: Ningxia, China
Key Offering: Industrial-Grade Cadaverine, Lysine Derivatives
Ningxia Eppen Biotechnology is the second-largest producer of 1,5-pentanediamine, capturing a significant share of the Chinese market. The company benefits from its strategic location in a major industrial chemical zone and its strong foothold in the amino acids market, which provides a stable raw material base.
Innovation Initiatives:
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Focus on process optimization to reduce production costs
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Expansion into downstream applications of cadaverine
8️⃣ 3. Thermo Fisher Scientific Inc.
Headquarters: Waltham, Massachusetts, USA
Key Offering: Reagent-Grade Cadaverine, Laboratory Chemicals
Thermo Fisher Scientific is a key global supplier of high-purity 1,5-pentanediamine for research and laboratory applications. While not a bulk industrial producer, the company serves the critical scientific and pharmaceutical research sectors with certified, high-quality materials that meet stringent analytical standards.
Innovation Initiatives:
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Providing ultra-pure grades for pharmaceutical R&D and analytical testing
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Developing specialized chemical portfolios for life sciences
7️⃣ 4. Merck KGaA (Sigma-Aldrich)
Headquarters: Darmstadt, Germany
Key Offering: High-Purity 1,5-pentanediamine, Specialty Biochemicals
Merck KGaA, through its Sigma-Aldrich brand, is a leading global provider of specialty chemicals, including high-purity cadaverine. The company caters primarily to the research, pharmaceutical, and fine chemical industries, offering products that adhere to the highest quality and consistency standards.
Innovation Initiatives:
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Supplying GMP-grade materials for pharmaceutical development
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Investment in bio-based chemical innovation through its life science division
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1,5-pentanediamine (Cadaverine) Market – View in Detailed Research Report
6️⃣ 5. Ajinomoto Co., Inc.
Headquarters: Tokyo, Japan
Key Offering: Amino Acids, Bio-based Chemicals
Ajinomoto, a world leader in amino acids, has the technological capability and infrastructure for 1,5-pentanediamine production. The company’s deep expertise in fermentation technology positions it as a potential significant player, particularly for bio-derived chemical intermediates in the Asian market.
Innovation Initiatives:
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Leveraging amino acid platform for bio-chemical diversification
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Exploring sustainable material applications for its chemical portfolio
5️⃣ 6. Toray Industries, Inc.
Headquarters: Tokyo, Japan
Key Offering: Bio-based Nylon (PA5X), Chemical Intermediates
Toray Industries is a major integrated chemical company with a strong focus on advanced materials. While primarily a downstream consumer of cadaverine for its bio-based nylon production, Toray’s significant R&D efforts in bio-polymers make it an influential force in driving demand and application innovation.
Innovation Initiatives:
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Pioneering development and commercialization of bio-based polyamide 5X
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Commitment to sustainability through biomass-derived material solutions
4️⃣ 7. BASF SE
Headquarters: Ludwigshafen, Germany
Key Offering: Specialty Chemicals, Polymer Intermediates
BASF, one of the world’s largest chemical producers, has a vested interest in bio-based intermediates like 1,5-pentanediamine. The company’s extensive R&D capabilities and broad market reach position it to play a key role in developing new applications and production technologies for sustainable diamines.
Innovation Initiatives:
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Research into catalytic processes for bio-based chemical production
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Development of sustainable material solutions across its value chains
3️⃣ 8. BOC Sciences
Headquarters: Shirley, New York, USA
Key Offering: Pharmaceutical Intermediates, Custom Synthesis
BOC Sciences is a specialty chemical supplier providing 1,5-pentanediamine primarily for research, pharmaceutical, and custom synthesis applications. The company serves niche markets that require high-purity, small-volume supplies for development and specialized industrial uses.
Innovation Initiatives:
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Custom synthesis services for derivative development
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Supply chain support for pharmaceutical and agrochemical R&D
2️⃣ 9. Evonik Industries AG
Headquarters: Essen, Germany
Key Offering: Specialty Chemicals, Performance Materials
Evonik Industries has strong capabilities in amine chemistry and biotechnology, making it a potential entrant or partner in the cadaverine market. The company’s focus on high-growth megatrends, including sustainability, aligns with the development of bio-based intermediates like 1,5-pentanediamine.
Innovation Initiatives:
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Expertise in white biotechnology and fermentation processes
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Active in developing sustainable alternatives for various industrial applications
1️⃣ 10. Kemin Industries
Headquarters: Des Moines, Iowa, USA
Key Offering: Specialty Ingredients, Biochemicals
Kemin Industries specializes in bio-based ingredients for various industries. While not a primary producer, its expertise in applied biotechnology and ingredient science positions it as a potential innovator in developing specialized applications for 1,5-pentanediamine, particularly in the life sciences and agricultural sectors.
Innovation Initiatives:
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Application development for specialty biochemicals
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Focus on sustainable and bio-based ingredient solutions
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1,5-pentanediamine (Cadaverine) Market – View in Detailed Research Report
🌍 Outlook: The Future of 1,5-pentanediamine Is Sustainable and Application-Driven
The 1,5-pentanediamine market is undergoing a significant transformation. While traditional chemical synthesis methods are still employed, the industry is increasingly investing in bio-based production, advanced fermentation technologies, and novel application pathways.
📈 Key Trends Shaping the Market:
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Rapid expansion of bio-based polyamide production in Asia and Europe
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Growing R&D investment in pharmaceutical and agricultural applications
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Technological advancements improving fermentation yields and cost-effectiveness
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Increasing regulatory and consumer pressure for sustainable chemical alternatives
Get Full Report Here:
1,5-pentanediamine (Cadaverine) Market – View in Detailed Research Report
The companies listed above are not only supplying a critical biochemical intermediate—they’re spearheading the transition to a more sustainable chemical industry.
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