The Global Nootkatone Market was valued at US$ 8 million in 2022 and is projected to reach US$ 28 million by 2029, growing at a Compound Annual Growth Rate (CAGR) of 19.2% during the forecast period. This remarkable growth is primarily driven by increasing consumer demand for natural ingredients in flavors and fragrances, the rising popularity of citrus-based personal care products, and the expanding applications of nootkatone as a natural insect repellent.

As the market for natural and sustainable ingredients continues to expand, the focus shifts to the key manufacturers and innovators who are shaping the supply and development of this valuable compound. In this blog, we profile the Top 10 Companies in the Nootkatone Industry—a dynamic mix of biotechnology pioneers, flavor and fragrance giants, and specialty chemical producers leading the global market.

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🔟 1. Evolva

Headquarters: Reinach, Switzerland
Key Offering: Biotechnology-derived Nootkatone

Evolva is the undisputed global leader in the nootkatone market, accounting for approximately 55% of global sales. The company utilizes advanced fermentation technology to produce high-purity, sustainable nootkatone, offering a reliable and scalable alternative to traditional extraction methods from grapefruit.

Key Market Initiatives:

• Pioneering fermentation-based production for consistent supply

• Strategic partnerships with major flavor and fragrance houses

• Focus on sustainable and non-GMO production processes

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9️⃣ 2. Isobionics

Headquarters: Geleen, Netherlands
Key Offering: Bio-based Nootkatone (Valencene conversion)

Isobionics, a subsidiary of BASF, is a major player specializing in the production of natural flavors and fragrances through biotechnological processes. The company is renowned for its efficient conversion of valencene to nootkatone, providing a high-quality, natural ingredient for various applications.

Key Market Initiatives:

• Expertise in bioconversion technologies for cost-effective production

• Strong positioning within the BASF nutrition and care portfolio

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8️⃣ 3. International Flavors & Fragrances Inc. (IFF)

Headquarters: New York, USA
Key Offering: Nootkatone for flavor and fragrance applications

IFF is a global leader in the creation of scents and tastes, and a significant consumer of nootkatone for its product lines. The company leverages its extensive R&D capabilities to integrate nootkatone into sophisticated flavor and fragrance compositions for consumer goods worldwide.

Key Market Initiatives:

• Extensive application development for food, beverage, and perfume industries

• Commitment to sourcing sustainable and natural ingredients

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7️⃣ 4. Vishal Essential

Headquarters: Mumbai, India
Key Offering: Essential oils and natural aroma chemicals, including nootkatone

Vishal Essential is a key supplier in the essential oils market, providing natural ingredients to various industries. The company is involved in the sourcing and supply of nootkatone, catering to the growing demand in the Asian market.

Key Market Initiatives:

• Strong supply chain networks for natural raw materials

• Focus on the expanding flavors and fragrances market in India and Southeast Asia

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6️⃣ 5. Puyi Biology

Headquarters: China
Key Offering: Nootkatone and other natural isolates

Puyi Biology is an emerging player in the natural ingredients sector, with a focus on the extraction and purification of high-value compounds. The company contributes to the global supply of nootkatone, particularly serving the domestic Chinese market and export clients.

Key Market Initiatives:

• Investment in extraction and purification technologies

• Capitalizing on China’s growing domestic demand for premium flavors

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5️⃣ 6. Aromor

Headquarters: Israel
Key Offering: Specialty fragrance ingredients and citrus derivatives

Aromor specializes in the development and production of high-value fragrance ingredients from citrus and other natural sources. The company’s expertise in citrus chemistry positions it as a knowledgeable supplier in the nootkatone market.

Key Market Initiatives:

• Focus on innovation in natural fragrance materials

• Strategic location with access to citrus raw materials

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4️⃣ 7. Penta Manufacturing Company

Headquarters: Livingston, New Jersey, USA
Key Offering: Pharmaceutical and fine chemical ingredients, including nootkatone

Penta Manufacturing is a leading international supplier of fine chemicals, flavors, and fragrances. The company offers nootkatone as part of its extensive portfolio of aroma chemicals, serving diverse industrial needs with a focus on quality and purity.

Key Market Initiatives:

• Distribution of high-purity chemicals to a global customer base

• Strong presence in the North American market

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3️⃣ 8. Alfrebro LLC

Headquarters: Cincinnati, Ohio, USA
Key Offering: Natural aroma chemicals and flavor ingredients

Alfrebro is a supplier of natural isolates and specialty ingredients for the flavor and fragrance industry. The company provides nootkatone sourced from natural origins, supporting the demand for authentic citrus notes in various applications.

Key Market Initiatives:

• Emphasis on natural and plant-derived ingredients

• Customer-focused approach with tailored solutions

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2️⃣ 9. Indenta Chemicals

Headquarters: Mumbai, India
Key Offering: Aroma chemicals and essential oil constituents

Indenta Chemicals is a manufacturer and exporter of aroma chemicals with a significant presence in the Indian subcontinent. The company is involved in the production and supply of key flavor and fragrance molecules, including nootkatone.

Key Market Initiatives:

• Cost-effective manufacturing capabilities

• Expanding export operations to global markets

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1️⃣ 10. Beijing Lys Chemicals

Headquarters: Beijing, China
Key Offering: Synthetic and natural flavor & fragrance ingredients

Beijing Lys Chemicals is a Chinese supplier active in the chemical sector, providing a range of ingredients to the flavor and fragrance industry. The company contributes to the regional supply chain for nootkatone, supporting local manufacturing needs.

Key Market Initiatives:

• Serving the rapidly growing APAC flavors and fragrances market

• Investment in scaling production capacities for high-demand ingredients

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🌍 Outlook: The Future of Nootkatone is Natural and High-Growth

The nootkatone market is on a steep growth trajectory, fueled by the powerful consumer shift toward naturality and sustainability. While traditional extraction methods face challenges of supply volatility and cost, the industry is increasingly embracing biotechnological innovations to ensure a stable and scalable supply of this prized ingredient.

📈 Key Trends Shaping the Market:

• Dominance of biotechnology: Fermentation and bioconversion processes are set to capture a larger market share due to their sustainability and scalability.

• Regulatory tailwinds: Growing approvals for nootkatone as a safe and effective natural insect repellent, such as by the US EPA, are opening new application avenues.

• Premiumization in F&F: High demand for natural and authentic citrus notes in premium beverages, perfumes, and personal care products.

• Geographic expansion: Increasing consumption in emerging markets across Asia-Pacific and Latin America.

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Nootkatone Market – View in Detailed Research Report

The companies listed above are not only supplying a key ingredient—they are at the forefront of the natural product revolution, driving innovation that defines the future of flavors, fragrances, and biocontrol.