Top 10 Companies in the Colistin Sulphate Market (2025): Key Players Shaping Global Animal Healthcare

In Business Insights
November 17, 2025


The Global Colistin Sulphate Market was valued at USD 60 Million in 2021 and is projected to reach USD 70 Million by 2028, growing at a Compound Annual Growth Rate (CAGR) of 2.4% during the forecast period (2022–2028). This steady growth is primarily driven by the persistent demand for effective treatments against Gram-negative bacterial infections in livestock, particularly in the pork and poultry industries, despite increasing global concerns over antimicrobial resistance (AMR).

As the veterinary pharmaceuticals sector navigates the dual challenges of ensuring animal health and promoting responsible antibiotic use, the focus intensifies on the key manufacturers who are driving production, innovation, and regulatory compliance. In this blog, we profile the Top 10 Companies in the Colistin Sulphate Industry—a group of API specialists and integrated pharmaceutical players critical to global animal protein production.

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🔟 1. Shengxue Dacheng

Headquarters: Hubei, China
Key Offering: Colistin Sulphate API, Colistin Sulphate Premix

Shengxue Dacheng is a significant manufacturer of Colistin Sulphate, specializing in the production of the active pharmaceutical ingredient (API) and its formulated premixes. The company serves both domestic Chinese and international veterinary markets, playing a crucial role in the supply chain for medicated animal feed.

Key Market Initiatives:

  • Focus on high-purity Colistin Sulphate API production

  • Integration into the animal feed additive value chain

  • Adherence to evolving regulatory standards for veterinary antibiotics


9️⃣ 2. Apeloa

Headquarters: Zhejiang, China
Key Offering: Colistin Sulphate API

Apeloa is a leading pharmaceutical company in China with a strong portfolio of APIs, including Colistin Sulphate. The company’s advanced manufacturing capabilities and significant production scale make it a key supplier to formulation companies worldwide.

Key Market Initiatives:

  • Investment in GMP-compliant manufacturing facilities

  • Strategic positioning in the global antibiotics market


8️⃣ 3. Livzon Group

Headquarters: Guangdong, China
Key Offering: Colistin Sulphate API and Finished Formulations

Livzon Pharmaceutical Group is a diversified pharmaceutical giant with a substantial presence in the veterinary antibiotics segment. The company produces Colistin Sulphate and leverages its extensive distribution network across Asia.

Key Market Initiatives:

  • Vertical integration from API to finished dosage forms

  • Expansion of veterinary pharmaceutical portfolio


7️⃣ 4. LKPC

Headquarters: Liaoning, China
Key Offering: Colistin Sulphate Premix

Lukang Pharmaceutical (LKPC) is a major player in the pharmaceutical industry, with a dedicated focus on veterinary products. The company is a prominent supplier of Colistin Sulphate Premix, used extensively in pig and chicken farming.

Key Market Initiatives:

  • Specialization in medicated feed premixes

  • Focus on product quality and consistency for livestock health

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Colistin Sulphate Market – View in Detailed Research Report


6️⃣ 5. Xellia

Headquarters: Copenhagen, Denmark
Key Offering: Colistin Sulphate API

Xellia Pharmaceuticals is a global leader in anti-infective treatments. While having a strong focus on human health, the company’s expertise in fermentation technology positions it as a key supplier of high-quality Colistin Sulphate API for veterinary applications, adhering to stringent international quality standards.

Key Market Initiatives:

  • Application of advanced fermentation and purification technologies

  • Commitment to manufacturing excellence and regulatory compliance


5️⃣ 6. Shenghua Biok

Headquarters: Shandong, China
Key Offering: Colistin Sulphate API and Premix

Shenghua Biok is a biotechnology company specializing in veterinary antibiotics and feed additives. The company is an important manufacturer of Colistin Sulphate, catering to the needs of the intensive livestock farming sector.

Key Market Initiatives:

  • Biotech-driven approach to antibiotic production

  • Strong distribution network within China’s agricultural regions


4️⃣ 7. Qianjiang Biochemical

Headquarters: Zhejiang, China
Key Offering: Colistin Sulphate API

Qianjiang Biochemical is a well-established manufacturer of pharmaceutical raw materials, including Colistin Sulphate. The company has a long history in the chemical and pharmaceutical industry and contributes significantly to the global supply of this critical veterinary antibiotic.

Key Market Initiatives:

  • Long-standing expertise in chemical synthesis and fermentation

  • Focus on cost-effective production for competitive pricing


3️⃣ 8. Lifecome

Headquarters: Jiangsu, China
Key Offering: Colistin Sulphate Premix

Lifecome Biochemistry is a manufacturer focused on veterinary pharmaceuticals and feed additives. The company produces Colistin Sulphate Premix, supplying integrators in the poultry and swine industries.

Key Market Initiatives:

  • Production tailored for feed mill applications

  • Emphasis on product stability and efficacy in animal feed


2️⃣ 9. Hainan Zhongxing

Headquarters: Hainan, China
Key Offering: Colistin Sulphate API

Hainan Zhongxing is a producer of pharmaceutical intermediates and APIs, including Colistin Sulphate. The company leverages its geographic location and manufacturing capabilities to serve both domestic and international markets.

Key Market Initiatives:

  • Strategic manufacturing base in Southern China

  • Focus on export-oriented API production


1️⃣ 10. Other Prominent Manufacturers

Overview: A collective of regional and specialized manufacturers
Key Offering: Colistin Sulphate API and Premix for local markets

Beyond the top listed companies, several other regional players contribute to the global Colistin Sulphate supply. These manufacturers often cater to specific geographic markets or specialized segments within the animal health industry, ensuring a diversified and resilient supply chain.

Key Market Role:

  • Serve niche markets and regional demands

  • Provide supply chain alternatives and redundancy

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Colistin Sulphate Market – View in Detailed Research Report


🌍 Outlook: Navigating the Future of Colistin Sulphate in a Responsible Use Era

The Colistin Sulphate market is at a pivotal juncture. While it remains a critical tool for controlling bacterial diseases in livestock, the industry is increasingly governed by regulations aimed at curbing antimicrobial resistance. The future will be shaped by a balance between animal welfare needs and global public health priorities.

📈 Key Trends Shaping the Market:

  • Strengthening global regulations restricting the use of Colistin as a growth promoter

  • Increasing focus on prudent use principles and veterinary oversight

  • Growth in demand from emerging economies with expanding livestock sectors

  • Rising investments in alternatives, such as vaccines, probiotics, and biosecurity measures

Get Full Report Here:
Colistin Sulphate Market – View in Detailed Research Report

The companies profiled above are essential suppliers in the global animal health landscape, navigating a complex regulatory environment to ensure the availability of a vital veterinary therapeutic while contributing to the broader goal of sustainable livestock production.