The Global Biocatalysis & Biocatalysts Market was valued at USD 5.72 Billion in 2024 and is projected to reach USD 11.86 Billion by 2032, growing at a Compound Annual Growth Rate (CAGR) of 9.3% during the forecast period (2024–2032). This significant expansion is fueled by the escalating demand for sustainable chemical manufacturing, stringent environmental regulations, and the rapid adoption of enzyme technologies in the pharmaceutical and food industries.

As industries worldwide pivot towards green chemistry and circular economy principles, the strategic importance of biocatalyst developers has never been greater. In this analysis, we profile the Top 10 Companies in the Biocatalysis & Biocatalysts Industry—a dynamic mix of established chemical giants, specialized enzyme producers, and pioneering biotech firms that are reshaping industrial processes for a more sustainable future.

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🔟 1. BASF SE

Headquarters: Ludwigshafen, Germany
Key Offering: Chiral catalysts, immobilized enzymes, custom biocatalyst solutions

BASF stands as a global leader in specialty chemicals and biocatalysis, leveraging its extensive R&D capabilities to develop advanced enzyme formulations for industrial applications. The company’s biocatalyst portfolio is particularly strong in producing chiral intermediates for pharmaceuticals and high-value chemicals, utilizing both free and immobilized enzymes.

Sustainability Initiatives:

• Development of bio-based routes for chemical synthesis

• Strategic partnerships with pharmaceutical companies for API manufacturing

• Commitment to carbon-neutral growth by 2050

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9️⃣ 2. Novozymes A/S

Headquarters: Bagsværd, Denmark
Key Offering: Hydrolases, oxidoreductases, specialty enzymes for various industries

Novozymes is the world’s largest enzyme manufacturer, with a comprehensive portfolio serving biofuels, food & beverages, detergents, and agricultural sectors. The company’s microbial technology platform enables the development of customized enzyme solutions for complex industrial challenges.

Sustainability Initiatives:

• Pioneering enzyme technologies for waste valorization

• Bioinnovation partnerships for circular economy solutions

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8️⃣ 3. DuPont de Nemours, Inc.

Headquarters: Wilmington, Delaware, USA
Key Offering: Industrial enzymes, biocatalyst systems, enzyme engineering services

DuPont maintains a strong position in biocatalysis through its industrial biosciences division, offering innovative enzyme solutions for food processing, biofuels, and pharmaceutical applications. The company’s expertise spans enzyme discovery, protein engineering, and process optimization.

Sustainability Initiatives:

• Advancement of bio-based production methods

• Development of enzymes for plastic recycling

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7️⃣ 4. Codexis, Inc.

Headquarters: Redwood City, California, USA
Key Offering: Engineered enzymes, biocatalyst screening platforms, process development

Codexis specializes in protein engineering and enzyme optimization, using its proprietary CodeEvolver® platform to create highly efficient biocatalysts for pharmaceutical and fine chemical synthesis. The company’s technology enables rapid development of custom enzymes with enhanced performance characteristics.

Sustainability Initiatives:

• Focus on green chemistry applications

• Partnerships for sustainable manufacturing processes

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6️⃣ 5. Royal DSM N.V.

Headquarters: Heerlen, Netherlands
Key Offering: Specialty enzymes, microbial solutions, biocatalytic processes

DSM offers a diverse range of biocatalyst solutions through its biotechnology division, with strong applications in food, feed, and pharmaceutical industries. The company’s expertise in fermentation technology and enzyme production supports sustainable manufacturing across multiple sectors.

Sustainability Initiatives:

• Development of bio-based alternatives to chemical processes

• Commitment to circular economy principles

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5️⃣ 6. Amano Enzyme Inc.

Headquarters: Nagoya, Japan
Key Offering: Food-grade enzymes, pharmaceutical intermediates, diagnostic enzymes

Amano Enzyme is a leading Japanese manufacturer specializing in high-purity enzymes for food processing, pharmaceutical, and diagnostic applications. The company’s strength lies in its extensive library of microbial enzymes and rigorous quality control standards.

Sustainability Initiatives:

• Development of enzymes for food waste reduction

• International expansion of sustainable enzyme solutions

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4️⃣ 7. Chr. Hansen Holding A/S

Headquarters: Hørsholm, Denmark
Key Offering: Microbial cultures, enzymes for dairy and food industries

Chr. Hansen is a global leader in microbial solutions, with a growing biocatalyst division focused on food enzymes and fermentation technologies. The company’s expertise in microbiology supports innovative enzyme applications across food processing and health sectors.

Sustainability Initiatives:

• Development of natural enzyme solutions for food preservation

• Circular economy approaches to enzyme production

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3️⃣ 8. AB Enzymes GmbH

Headquarters: Darmstadt, Germany
Key Offering: Specialty enzymes for food, feed, and technical applications

AB Enzymes, a subsidiary of Associated British Foods, specializes in developing high-performance enzyme solutions for baking, animal nutrition, and industrial processes. The company’s focus on application-specific formulations ensures optimal performance across diverse industrial settings.

Sustainability Initiatives:

• Enzyme solutions for energy-efficient processing

• Sustainable sourcing of raw materials

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2️⃣ 9. Dyadic International, Inc.

Headquarters: Jupiter, Florida, USA
Key Offering: C1 fungal expression platform, industrial enzyme production

Dyadic specializes in developing and licensing its proprietary C1 microbial expression system for efficient enzyme production. The company’s technology platform enables cost-effective manufacturing of industrial enzymes at commercial scale.

Sustainability Initiatives:

• Focus on scalable biocatalyst production

• Partnerships for bio-based chemical manufacturing

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1️⃣ 10. Lonza Group AG

Headquarters: Basel, Switzerland
Key Offering: Custom biocatalysis services, enzyme screening, process development

Lonza provides comprehensive biocatalysis services to pharmaceutical and chemical industries, offering custom enzyme development and process optimization solutions. The company’s expertise spans enzyme discovery, engineering, and scale-up for industrial applications.

Sustainability Initiatives:

• Development of green chemistry processes

• Integration of biocatalysis in pharmaceutical manufacturing

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🌍 Outlook: The Future of Biocatalysis is Intelligent and Sustainable

The biocatalysis market is experiencing transformative growth as industries embrace enzyme technologies for cleaner, more efficient manufacturing. While chemical synthesis still dominates many processes, companies are increasingly investing in smart biocatalyst solutions that combine biological precision with digital optimization.

📈 Key Trends Shaping the Market:

• Accelerated adoption of AI-driven enzyme design and optimization

• Growing regulatory support for green chemistry initiatives worldwide

• Expansion of biocatalysis in pharmaceutical continuous manufacturing

• Strategic partnerships between enzyme manufacturers and end-user industries

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The companies profiled above are not merely supplying enzymes—they’re actively engineering the future of sustainable manufacturing across global industries.

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