The Global Vericiguat API Market was valued at US$ 48.7 Million in 2024 and is projected to reach US$ 79.2 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 8.5% during the forecast period (2024–2030). This significant growth is primarily driven by the rising global prevalence of chronic heart failure (CHF), increasing adoption of novel soluble guanylate cyclase (sGC) stimulators, and expanding clinical research into new cardiovascular indications.

As the pharmaceutical industry intensifies its focus on innovative heart failure treatments, the Active Pharmaceutical Ingredient (API) manufacturers supplying Vericiguat are playing a critical role. These companies ensure the production of high-purity, compliant raw materials essential for formulating the final drug product. In this blog, we profile the Top 10 Companies in the Vericiguat API Industry—a diverse group of specialized chemical suppliers, research chemical providers, and pharmaceutical ingredient manufacturers shaping the supply chain for this vital cardiovascular therapy.

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🔟 1. Cayman Chemical

Headquarters: Ann Arbor, Michigan, USA
Key Offering: High-Purity Vericiguat API for Research Use

Cayman Chemical is a leading global supplier of biochemicals for research, including high-quality Vericiguat API. The company serves pharmaceutical companies, academic institutions, and contract research organizations (CROs) worldwide, providing the critical raw material needed for drug development and preclinical studies.

Product Development Initiatives:

• Supply of Vericiguat for investigative new drug (IND) enabling studies

• Comprehensive analytical data and certificates of analysis (CoA)

• Support for regulatory submissions with GMP-grade materials

Download FREE Sample Report: Vericiguat API Market – View in Detailed Research Report

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9️⃣ 2. MedKoo Biosciences

Headquarters: Morrisville, North Carolina, USA
Key Offering: Vericiguat for laboratory research and development

MedKoo Biosciences specializes in providing novel life science reagents and APIs, including Vericiguat, to the global research community. The company is recognized for its rapid synthesis capabilities and ability to supply hard-to-find chemical compounds for pharmaceutical R&D.

Product Development Initiatives:

• Custom synthesis services for Vericiguat analogs and metabolites

• Scale-up capabilities from milligram to kilogram quantities

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8️⃣ 3. Taiclone

Headquarters: Shanghai, China
Key Offering: Vericiguat API for pharmaceutical applications

Taiclone is a specialized manufacturer of pharmaceutical intermediates and APIs, with expertise in complex molecules like Vericiguat. The company serves both domestic Chinese pharmaceutical companies and international clients seeking reliable API supply chains.

Product Development Initiatives:

• Cost-effective synthesis routes for Vericiguat production

• Strict quality control compliant with international standards

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7️⃣ 4. Clearsynth

Headquarters: Mumbai, India
Key Offering: High-purity Vericiguat reference standards and APIs

Clearsynth is a global supplier of high-purity pharmaceutical reference standards and APIs, including Vericiguat. The company provides materials that meet pharmacopoeial standards, supporting quality control and analytical development in pharmaceutical manufacturing.

Product Development Initiatives:

• Development of Vericiguat metabolites and degradation products

• Stable isotope-labeled Vericiguat for bioanalytical applications

Download FREE Sample Report: Vericiguat API Market – View in Detailed Research Report

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6️⃣ 5. CSNpharm

Headquarters: Arlington Heights, Illinois, USA
Key Offering: Vericiguat API for research and pharmaceutical development

CSNpharm is a supplier of chemical reagents and APIs for drug discovery and development, offering Vericiguat to research institutions and pharmaceutical companies. The company focuses on providing compounds with comprehensive analytical characterization.

Product Development Initiatives:

• Supply of Vericiguat with detailed spectroscopic data

• Bulk quantities for preclinical and clinical trial material needs

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5️⃣ 6. TargetMol Chemicals

Headquarters: Boston, Massachusetts, USA
Key Offering: Vericiguat for screening libraries and research applications

TargetMol Chemicals provides a comprehensive collection of bioactive molecules, including Vericiguat, for drug screening and pharmacological research. The company serves the global pharmaceutical and biotechnology sectors with high-quality chemical tools.

Product Development Initiatives:

• Inclusion of Vericiguat in targeted screening libraries

• Structure-activity relationship (SAR) studies support

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4️⃣ 7. AbMole BioScience

Headquarters: Houston, Texas, USA
Key Offering: Vericiguat for academic and pharmaceutical research

AbMole BioScience specializes in providing high-quality inhibitors, agonists, and APIs for scientific research, with Vericiguat as part of their cardiovascular research portfolio. The company supports researchers with reliable compound supply and technical information.

Product Development Initiatives:

• Technical support for Vericiguat application in research models

• Batch-to-batch consistency for long-term research projects

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3️⃣ 8. Toronto Research Chemicals

Headquarters: Toronto, Ontario, Canada
Key Offering: Vericiguat and related metabolites for analytical applications

Toronto Research Chemicals (TRC) is a leading manufacturer of biochemicals for research, offering Vericiguat and its metabolites to support pharmaceutical analysis and metabolism studies. TRC is known for its high purity standards and comprehensive product documentation.

Product Development Initiatives:

• Development of Vericiguat impurity standards

• Metabolite synthesis for drug metabolism and pharmacokinetics (DMPK) studies

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2️⃣ 9. Metrochem

Headquarters: Hyderabad, India
Key Offering: GMP-grade Vericiguat API for commercial manufacturing

Metrochem is an established Indian API manufacturer with capabilities in producing Vericiguat under Good Manufacturing Practice (GMP) conditions. The company supplies regulated markets and supports generic drug manufacturers with quality APIs.

Product Development Initiatives:

• Scale-up of Vericiguat synthesis for commercial production

• Regulatory support for drug master files (DMFs)

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1️⃣ 10. Maithri Drugs

Headquarters: Hyderabad, India
Key Offering: Vericiguat API for pharmaceutical formulations

Maithri Drugs is a pharmaceutical company with API manufacturing capabilities, including the production of Vericiguat. The company focuses on cost-effective manufacturing while maintaining quality standards required for cardiovascular therapeutics.

Product Development Initiatives:

• Process optimization for efficient Vericiguat manufacturing

• Partnerships with formulation companies for integrated supply

Get Full Report Here: Vericiguat API Market – View in Detailed Research Report

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🌍 Outlook: The Future of Vericiguat API Is Precision and Accessibility

The Vericiguat API market is experiencing transformative growth as heart failure treatment paradigms evolve. While current production supports the branded medication, the industry is preparing for patent expirations and the subsequent entry of generic versions, which will significantly expand market access.

📈 Key Trends Shaping the Market:

• Increasing generic API manufacturing capacity in Asia-Pacific regions

• Growing research into Vericiguat combinations with other heart failure therapies

• Advancements in synthetic routes for improved yield and purity

• Regulatory harmonization for sGC stimulator APIs across major markets

Get Full Report Here: Vericiguat API Market – View in Detailed Research Report

The companies listed above are not only supplying a critical cardiovascular API—they’re enabling the therapeutic advancement for millions of heart failure patients worldwide.