Top 10 Companies in the 4′-Chloroacetophenone Market (2025): Key Players in Pharmaceutical and Agrochemical Intermediates

In Business Insights
November 16, 2025

The Global 4′-Chloroacetophenone Market was valued at USD 112.5 Million in 2024 and is projected to reach USD 158.3 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 5.8% during the forecast period (2024–2030). This sustained growth is primarily driven by the expanding pharmaceutical industry, where 4′-Chloroacetophenone serves as a critical building block for active pharmaceutical ingredients (APIs), and its increasing application in agrochemical synthesis for herbicides and pesticides.

As the demand for specialized chemicals intensifies across life sciences and crop protection sectors, key manufacturers are focusing on capacity expansion, process optimization, and maintaining stringent quality standards. In this blog, we profile the Top 10 Companies in the 4′-Chloroacetophenone Industry—a group of established chemical producers and specialty intermediates suppliers shaping the global supply chain.


🔟 1. Haihang Industry Co., Ltd.

Headquarters: Jinan, Shandong, China
Key Offering: High-Purity 4′-Chloroacetophenone (98% min, 99% min)

Haihang Industry is a leading Chinese manufacturer and global supplier of fine chemicals, including 4′-Chloroacetophenone. The company has established a strong presence by offering competitive pricing and reliable supply chains, catering to both domestic and international markets in the pharmaceutical and agrochemical sectors.

Strategic Initiatives:

  • Continuous process optimization for higher yield and purity

  • Expansion of export capabilities to North America and Europe

  • Investment in R&D for derivative applications

Download FREE Sample Report: 4′-Chloroacetophenone Market – View in Detailed Research Report


9️⃣ 2. Santa Cruz Biotechnology, Inc.

Headquarters: Dallas, Texas, USA
Key Offering: Research Grade 4′-Chloroacetophenone, Analytical Standards

Santa Cruz Biotechnology is a major supplier of biochemicals and reagents for research applications. Their high-purity 4′-Chloroacetophenone is widely used in academic, pharmaceutical R&D, and biotech laboratories for synthesis and analytical purposes, supported by comprehensive technical data and documentation.

Strategic Initiatives:

  • Focus on high-purity grades for research and development

  • Maintaining a broad portfolio of related chemical intermediates


8️⃣ 3. Hangzhou J&H Chemical Co., Ltd.

Headquarters: Hangzhou, Zhejiang, China
Key Offering: 4′-Chloroacetophenone, Custom Synthesis Services

Hangzhou J&H Chemical specializes in the manufacturing and supply of pharmaceutical intermediates and fine chemicals. The company provides 4′-Chloroacetophenone with consistent quality and offers custom synthesis services to meet specific client requirements, serving a global customer base.

Strategic Initiatives:

  • Strong focus on custom manufacturing and contract research

  • Strategic partnerships with global pharmaceutical companies


7️⃣ 4. Alfa Aesar (Thermo Fisher Scientific)

Headquarters: Ward Hill, Massachusetts, USA
Key Offering: Laboratory Chemicals, 4′-Chloroacetophenone (various purities)

As part of Thermo Fisher Scientific, Alfa Aesar is a globally recognized supplier of research chemicals, metals, and materials. Their 4′-Chloroacetophenone is supplied with high-quality assurance, making it a preferred choice for R&D laboratories in pharmaceuticals and academia.

Strategic Initiatives:

  • Integration into Thermo Fisher’s global distribution network

  • Emphasis on quality control and regulatory compliance

Download FREE Sample Report: 4′-Chloroacetophenone Market – View in Detailed Research Report


6️⃣ 5. Tokyo Chemical Industry Co., Ltd. (TCI)

Headquarters: Tokyo, Japan
Key Offering: High-Purity Fine Chemicals, 4′-Chloroacetophenone

TCI is a leading global manufacturer and supplier of laboratory chemicals and fine chemicals. The company offers high-purity 4′-Chloroacetophenone, supported by extensive analytical data, catering to the stringent requirements of pharmaceutical and chemical research institutions worldwide.

Strategic Initiatives:

  • Global expansion of distribution centers

  • Investment in developing novel synthetic methodologies


5️⃣ 6. Sigma-Aldrich (Merck KGaA)

Headquarters: Darmstadt, Germany
Key Offering: 4′-Chloroacetophenone, Pharmaceutical Intermediates

Operating under Merck KGaA, Sigma-Aldrich is a premier life science and high-technology company. It supplies high-quality 4′-Chloroacetophenone to the pharmaceutical and biotechnology industries, backed by robust quality management systems and global logistics.

Strategic Initiatives:

  • Leveraging Merck’s global reach and R&D capabilities

  • Focus on sustainable and scalable production processes


4️⃣ 7. Lianyungang Zhaofeng Chemical Co., Ltd.

Headquarters: Lianyungang, Jiangsu, China
Key Offering: Industrial and Pharmaceutical Grade 4′-Chloroacetophenone

Lianyungang Zhaofeng Chemical is a specialized manufacturer of fine chemicals and intermediates, with significant production capacity for 4′-Chloroacetophenone. The company serves both the domestic Chinese market and international clients, with a focus on cost-effective manufacturing.

Strategic Initiatives:

  • Capacity expansion to meet growing global demand

  • Optimization of chlorination and Friedel-Crafts acylation processes


3️⃣ 8. AB Enterprises

Headquarters: Mumbai, Maharashtra, India
Key Offering: 4′-Chloroacetophenone, Custom Synthesis

AB Enterprises is an Indian supplier of fine chemicals, pharmaceutical intermediates, and specialty products. The company has carved a niche in supplying 4′-Chloroacetophenone to the growing Indian pharmaceutical sector, along with export operations to other regions.

Strategic Initiatives:

  • Capitalizing on India’s strong pharmaceutical manufacturing base

  • Development of cost-competitive synthesis routes


2️⃣ 9. Capot Chemical Co., Ltd.

Headquarters: Hangzhou, Zhejiang, China
Key Offering: 4′-Chloroacetophenone, Advanced Intermediates

Capot Chemical is a technology-driven company specializing in the research, development, and production of advanced chemical intermediates. Their 4′-Chloroacetophenone is produced with a focus on high purity and is used in the synthesis of more complex molecules for pharmaceutical applications.

Strategic Initiatives:

  • Strong emphasis on R&D and proprietary technology

  • Strategic focus on high-value pharmaceutical intermediates


1️⃣ 10. Win-Win Chemical Co., Ltd.

Headquarters: Suzhou, Jiangsu, China
Key Offering: 4′-Chloroacetophenone, Fine Chemicals

Win-Win Chemical is a supplier of fine chemicals and pharmaceutical intermediates, including 4′-Chloroacetophenone. The company serves a diverse clientele and emphasizes reliable supply, consistent quality, and competitive pricing in the global market.

Strategic Initiatives:

  • Building long-term partnerships with key industry players

  • Expanding product portfolio of related aromatic ketones

Get Full Report Here: 4′-Chloroacetophenone Market – View in Detailed Research Report


🧪 Market Segmentation and Regional Analysis

The research report includes specific segments by region (country), by company, by Type and by Application. This study provides information about the sales and revenue during the historic and forecasted period of 2015 to 2026. Understanding the segments helps in identifying the importance of different factors that aid the market growth.

Segment by Type, the 4′-Chloroacetophenone market is segmented into

  • Purity ≥98%
  • Purity ≥99%
  • Others

Segment by Application

  • Pharmaceutical Intermediates
  • Agrochemical Intermediates
  • Others

Global 4′-Chloroacetophenone Market: Regional Analysis

  • The 4′-Chloroacetophenone market is analysed and market size information is provided by regions (countries). The report includes country-wise and region-wise market size for the period 2015-2026. It also includes market size and forecast by Type and by Application segment in terms of sales and revenue for the period 2015-2026.

The key regions covered in the 4′-Chloroacetophenone market report are:

  • North America
  • U.S.
  • Canada
  • Europe
  • Germany
  • France
  • U.K.
  • Italy
  • Russia
  • Asia-Pacific
  • China
  • Japan
  • South Korea
  • India
  • Australia
  • Taiwan
  • Indonesia
  • Thailand
  • Malaysia
  • Philippines
  • Vietnam
  • Latin America
  • Mexico
  • Brazil
  • Argentina
  • Middle East & Africa
  • Turkey
  • Saudi Arabia
  • U.A.E

Global 4′-Chloroacetophenone Market: Competitive Analysis

  • This section of the report identifies various key manufacturers of the market. It helps the reader understand the strategies and collaborations that players are focusing on combat competition in the market. The comprehensive report provides a significant microscopic look at the market. The reader can identify the footprints of the manufacturers by knowing about the global revenue of manufacturers, the global price of manufacturers, and sales by manufacturers during the forecast period of 2015 to 2019.

The major players in global 4′-Chloroacetophenone market include:

  • Haihang Industry Co., Ltd.
  • Santa Cruz Biotechnology, Inc.
  • Hangzhou J&H Chemical Co., Ltd.
  • Alfa Aesar (Thermo Fisher Scientific)
  • Tokyo Chemical Industry Co., Ltd. (TCI)
  • Sigma-Aldrich (Merck KGaA)
  • Lianyungang Zhaofeng Chemical Co., Ltd.
  • AB Enterprises
  • Capot Chemical Co., Ltd.
  • Win-Win Chemical Co., Ltd.

Download FREE Sample Report: 4′-Chloroacetophenone Market – View in Detailed Research Report


🌍 Outlook: The Future of 4′-Chloroacetophenone is Tied to Innovation in End-Use Industries

The 4′-Chloroacetophenone market is experiencing steady growth, closely linked to the performance and innovation within the pharmaceutical and agrochemical sectors. While it remains a well-established intermediate, the focus is shifting towards higher purity grades, green synthesis methods, and the development of novel derivatives for advanced applications.

📈 Key Trends Shaping the Market:

  • Increasing demand for high-purity grades (≥99%) from the pharmaceutical industry

  • Geographic shift in manufacturing capacity towards Asia-Pacific, particularly China and India

  • Growing R&D into more efficient and environmentally friendly production processes

  • Rising application in the synthesis of new-generation agrochemicals

Get Full Report Here: 4′-Chloroacetophenone Market – View in Detailed Research Report

The companies listed above are not only supplying a crucial chemical intermediate—they are enabling the development of life-saving pharmaceuticals and efficient crop protection solutions worldwide.