The Global 1,3-Benzodioxole Market was valued at USD 241.8 Million in 2024 and is projected to reach USD 342.1 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 5.8% during the forecast period (2024–2030). This steady growth is primarily driven by the compound’s versatile applications as a crucial intermediate in the pharmaceutical, agrochemical, and fragrance industries, alongside rising demand for low-toxicity insecticides and specialty chemicals.
As industries increasingly prioritize efficient and sustainable chemical synthesis, the role of key producers of 1,3-Benzodioxole (CAS 274-09-9) becomes ever more critical. These companies are not only ensuring a stable supply of this essential building block but are also investing in cleaner production technologies and capacity expansions. In this blog, we profile the Top 10 Companies in the 1,3-Benzodioxole Market—a group of established chemical manufacturers and specialized intermediates producers shaping the future of this niche yet vital sector.
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🔟 1. Ube Industries, Ltd.
Headquarters: Tokyo, Japan
Key Offering: High-Purity 1,3-Benzodioxole (Purity 99%+)
Ube Industries is a leading Japanese chemical company with a strong portfolio in specialty chemicals and advanced materials. Its chemical division produces high-purity 1,3-Benzodioxole, which is critical for synthesizing complex molecules in pharmaceuticals and agrochemicals. The company’s integrated production processes and stringent quality control make it a preferred supplier for global customers.
Innovation & Market Focus:
- Focus on high-value, high-purity grades for pharmaceutical applications
- Continuous process optimization for improved yield and sustainability
- Strong R&D collaboration with end-user industries
9️⃣ 2. Endura S.p.A.
Headquarters: Key Offering: 1,3-Benzodioxole for Agrochemical Intermediates
Endura is a major Italian manufacturer of intermediates for the agrochemical and pharmaceutical sectors. The company has significant expertise in heterocyclic chemistry and produces 1,3-Benzodioxole as a key building block for active ingredients in crop protection products. Their strength lies in custom synthesis and scaling up production for specific client requirements.
Innovation & Market Focus:
- Specialization in intermediates for low-toxic insecticides
- Robust custom manufacturing capabilities
- Strategic focus on the European agrochemical market
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8️⃣ 3. Shandong Xinhua Pharmaceutical Co., Ltd.
Headquarters: Zibo, Shandong, China
Key Offering: 1,3-Benzodioxole (Purity 98%, 99%)
Shandong Xinhua Pharmaceutical is a prominent Chinese manufacturer of pharmaceutical intermediates and APIs. The company produces 1,3-Benzodioxole for both internal use in its drug manufacturing and for external sales. Its large-scale production capacity and competitive cost position make it a significant player in the Asian market.
Innovation & Market Focus:
- Vertical integration from basic chemicals to finished pharmaceuticals
- Large-scale, cost-effective production
- Expanding international sales network
7️⃣ 4. Changzhou Yabang Pharmaceutical Co., Ltd.
Headquarters: Changzhou, Jiangsu, China
Key Offering: Pharmaceutical-Grade 1,3-Benzodioxole
Changzhou Yabang Pharmaceutical specializes in the research, development, and production of pharmaceutical intermediates and APIs. The company utilizes 1,3-Benzodioxole in the synthesis of various therapeutic agents and offers it as a standalone intermediate. Their focus on cGMP-compliant manufacturing ensures high quality for sensitive pharmaceutical applications.
Innovation & Market Focus:
- cGMP-compliant manufacturing facilities
- Strong R&D focus on novel synthetic routes
- Strategic partnerships with global pharma companies
6️⃣ 5. Haimen Zhaofeng Chemical Co., Ltd.
Headquarters: Haimen, Jiangsu, China
Key Offering: 1,3-Benzodioxole for Fragrance and Pesticide Intermediates
Haimen Zhaofeng Chemical is a specialized producer of fine chemicals and intermediates, with 1,3-Benzodioxole being a key product. The company serves diverse end-markets, including fragrances (for compounds like jasmonal) and agrochemicals. Their flexibility in catering to different purity specifications is a notable strength.
Innovation & Market Focus:
- Diversified application base across fragrances and agrochemicals
- Flexible production for custom purity requirements
- Competitive pricing for volume buyers
5️⃣ 6. Laohekou Guanglian Technology Co., Ltd.
Headquarters: Laohekou, Hubei, China
Key Offering: Technical and Purified Grades of 1,3-Benzodioxole
Laohekou Guanglian Technology is an emerging chemical manufacturer in Central China with a focus on intermediates like 1,3-Benzodioxole. The company has been investing in capacity expansion to meet the growing domestic and international demand, particularly from the pesticide sector.
Innovation & Market Focus:
- Rapid capacity expansion to capture market growth
- Cost leadership strategy
- Focus on the Asian regional market
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4️⃣ 7. Northeast Pharmaceutical Group Co., Ltd.
Headquarters: Shenyang, Liaoning, China
Key Offering: 1,3-Benzodioxole for Pharmaceutical Synthesis
Northeast Pharmaceutical Group is one of China’s oldest and largest pharmaceutical manufacturers. The company has a comprehensive chemical synthesis platform and produces 1,3-Benzodioxole primarily for its internal drug production pipeline, with limited external sales. Its long-standing expertise in chemical processing is a key asset.
Innovation & Market Focus:
- Backward integration for secure supply of key intermediates
- Extensive experience in industrial-scale chemical production
- Focus on producing APIs for vitamins and antibiotics
3️⃣ 8. Capot Chemical Co., Ltd.
Headquarters: Hangzhou, Zhejiang, China
Key Offering: High-Purity 1,3-Benzodioxole and Derivatives
Capot Chemical is a leading supplier of fine chemicals, building blocks, and advanced intermediates for global research and development, as well as commercial production. While not a primary producer on the scale of others, it is a key distributor and supplier of high-purity 1,3-Benzodioxole for research institutions and pilot-scale projects.
Innovation & Market Focus:
- Specialization in high-purity chemicals for R&D
- Strong global distribution network
- Catalog offering of diverse benzodioxole derivatives
2️⃣ 9. Toronto Research Chemicals Inc. (TRC)
Headquarters: Toronto, Ontario, Canada
Key Offering: Analytical and Research Grade 1,3-Benzodioxole
Toronto Research Chemicals (TRC) is a world-renowned supplier of biochemicals for research purposes. TRC offers 1,3-Benzodioxole as a high-purity reference standard and research chemical. While its commercial volume is small, its role is critical for analytical methods development, toxicology studies, and early-stage drug discovery in pharmaceutical companies and academic labs worldwide.
Innovation & Market Focus:
- Production of certified reference materials (CRMs)
- Serving the life sciences and analytical testing markets
- Ultra-high purity standards for research applications
1️⃣ 10. Hangzhou J&H Chemical Co., Ltd.
Headquarters: Hangzhou, Zhejiang, China
Key Offering: 1,3-Benzodioxole for Custom Synthesis
Hangzhou J&H Chemical is a supplier and custom synthesis provider for pharmaceutical intermediates, agrochemical intermediates, and fine chemicals. The company sources and supplies 1,3-Benzodioxole and also offers custom synthesis services for related derivatives, catering to clients who require tailored molecular structures for their specific applications.
Innovation & Market Focus:
- Strong custom synthesis and contract manufacturing services
- Agile response to specific client molecule requirements
- Integration with a broad network of chemical manufacturers
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🌍 Outlook: The Future of 1,3-Benzodioxole is Driven by Green Chemistry and Specialization
The 1,3-Benzodioxole market is poised for sustained growth, underpinned by its irreplaceable role as a synthetic precursor. However, the industry’s future will be shaped by a stronger emphasis on sustainable production methods, regulatory compliance, and the development of novel applications beyond traditional sectors.
📈 Key Trends Shaping the Market:
- Increasing adoption of green chemistry principles to minimize waste and hazardous by-products in synthesis
- Growing demand for high-purity grades (99%+) from the pharmaceutical industry for complex API synthesis
- Stringent environmental regulations influencing production processes and waste management, particularly in Europe and North America
- Exploration of 1,3-Benzodioxole derivatives in new material science applications, such as polymers and electronic chemicals
- Capacity expansions in Asia, especially China, to consolidate their position as the global manufacturing hub
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1,3-Benzodioxole Market – View in Detailed Research Report
The companies listed above are at the forefront of supplying this essential chemical intermediate, navigating the challenges of cost, quality, and sustainability to fuel innovation across multiple high-value industries.
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