Top 10 Companies in the Sterilants and High Level Disinfectants Market (2025): Leading the Fight Against HAIs

In Business Insights
November 15, 2025


The Global Sterilants and High Level Disinfectants Market was valued at USD 5.8 Billion in 2024 and is projected to reach USD 9.2 Billion by 2030, growing at a Compound Annual Growth Rate (CAGR) of 7.9% during the forecast period (2024–2030). This robust growth is fueled by the persistent challenge of Healthcare-Associated Infections (HAIs), stringent regulatory requirements for sterilization and disinfection, the growing volume of surgical procedures, and the critical need to disinfect complex medical devices like endoscopes and ultrasound probes.

As healthcare facilities worldwide intensify their focus on patient safety and infection control protocols, the role of companies providing advanced sterilization and high-level disinfection (HLD) solutions has become paramount. In this blog, we profile the Top 10 Companies in the Sterilants and High Level Disinfectants Industry—a group of established leaders and innovators who are setting the standards for aseptic practices and combating antimicrobial resistance.


🔟 1. STERIS plc

Headquarters: Mentor, Ohio, USA
Key Offering: Sterility Assurance Products, CIDEX® OPA Solution, SYSTEM 1E® Liquid Chemical Sterilant

STERIS is a global leader in infection prevention, offering a comprehensive portfolio of sterilants, high-level disinfectants, and related equipment. The company’s solutions are critical for reprocessing medical devices in hospitals, ambulatory surgery centers, and pharmaceutical manufacturing.

Innovation Focus:

  • Development of automated endoscope reprocessors (AERs) and validation services

  • Expansion of single-use and low-temperature sterilization technologies

  • Leadership in regulatory compliance and sterile processing education

Download FREE Sample Report:
Sterilants and High Level Disinfectants Market – View in Detailed Research Report


9️⃣ 2. Cantel Medical (A Part of STERIS)

Headquarters: Chicago, Illinois, USA
Key Offering: ENDOCLENS® Endoscope Reprocessor, CIDEX® HLD Solutions, Instrument Processing

Following its acquisition by STERIS, Cantel Medical remains a powerhouse in endoscopy reprocessing and infection prevention. It provides a robust suite of high-level disinfectants, sterilants, and proprietary processing equipment trusted by healthcare facilities globally.

Innovation Focus:

  • Flagship CIDEX® solutions for high-level disinfection

  • Integrated systems for endoscopy workflow and compliance tracking


8️⃣ 3. Advanced Sterilization Products (ASP), A Division of Johnson & Johnson

Headquarters: Irvine, California, USA
Key Offering: STERRAD® Sterilization Systems, EVOTECH® ECR, ENDOCLENS® (via Cantel)

ASP is a world-renowned provider of low-temperature hydrogen peroxide gas plasma sterilization systems (STERRAD®) and high-level disinfectants. Its technologies are essential for heat-sensitive medical instruments, ensuring rapid turnover and patient safety.

Innovation Focus:

  • Pioneering low-temperature sterilization technologies

  • Advanced tracking and traceability solutions for sterile processing departments


7️⃣ 4. Metrex Research, LLC (Part of CaviCide)

Headquarters: Orange, California, USA
Key Offering: CaviCide® Surface Disinfectants, Metricide®, Opti-Cide3®

Metrex Research specializes in high-level disinfectants and sterilants for critical medical devices, along with a broad range of surface disinfectants. The company is known for its effective, user-friendly formulations that meet the demanding needs of modern healthcare.

Innovation Focus:

  • Development of fast-acting, broad-spectrum disinfectant chemistries

  • Focus on compatibility with delicate medical instruments


6️⃣ 5. B. Braun Melsungen AG

Headquarters: Melsungen, Germany
Key Offering: Peracetic Acid-based Sterilants, Sterillium®, TissueSAFE

B. Braun is a leading medical and pharmaceutical device company with a strong presence in infection control. Its sterilant and disinfectant portfolio is integral to its broader offering, supporting hospitals in maintaining aseptic conditions for surgeries and patient care.

Innovation Focus:

  • Expertise in peracetic acid (PAA) based low-temperature sterilization systems

  • Comprehensive solutions for hand hygiene, surface disinfection, and instrument reprocessing

Download FREE Sample Report:
Sterilants and High Level Disinfectants Market – View in Detailed Research Report


5️⃣ 6. SARAYA Co., Ltd.

Headquarters: Osaka, Japan
Key Offering: HibiTect® Disinfectants, HANDYPROTECT® Alcohol Sanitizers, Medical-Grade Disinfectants

SARAYA is a Japanese hygiene products specialist with a significant global footprint. The company manufactures a wide array of high-level disinfectants and sterilants, with a strong emphasis on biocompatibility and environmental sustainability.

Innovation Focus:

  • Development of plant-derived and biodegradable disinfectant formulations

  • Specialization in infection control for dental and pharmaceutical applications


4️⃣ 7. CS Medical LLC

Headquarters: Creedmoor, North Carolina, USA
Key Offering: Endoscope Drying and Storage Cabinets, TRU-D® SmartUVC, HLD Chemicals

CS Medical focuses specifically on the decontamination, drying, and storage of endoscopes. The company provides specialized equipment and chemicals that close critical gaps in the endoscope reprocessing cycle, directly addressing causes of HAIs.

Innovation Focus:

  • Leading-edge endoscope drying and storage technology to prevent biofilm formation

  • Integration of chemical disinfection with automated drying and tracking systems


3️⃣ 8. Ecolab Inc.

Headquarters: St. Paul, Minnesota, USA
Key Offering: OXY-STERIL®, ECOCIDE, Healthcare Environmental Hygiene Solutions

Ecolab is a global leader in water, hygiene, and infection prevention solutions. Its healthcare division provides powerful sterilants and disinfectants used in sterile processing departments, operating rooms, and across the healthcare facility.

Innovation Focus:

  • Data-driven infection prevention programs and consulting services

  • Sustainable chemistry and automated dispensing systems for accurate dilution


2️⃣ 9. Getinge AB

Headquarters: Gothenburg, Sweden
Key Offering: Getinge Sterilization Solutions, DISCOVERY STS®, High-Level Disinfectants

Getinge offers a complete range of sterilization and disinfection equipment and consumables for healthcare. Its solutions ensure the effective reprocessing of surgical instruments, contributing to safe patient care worldwide.

Innovation Focus:

  • Advanced steam sterilizers (autoclaves) and washer-disinfectors

  • Connectivity and software for tracking sterilization cycles and compliance


1️⃣ 10. 3M Company

Headquarters: St. Paul, Minnesota, USA
Key Offering: 3M™ Attest™ Biological Indicators, Steri-Vac™ Sterilizers, Disinfectants

3M’s Infection Prevention Division is a key player, providing critical monitoring solutions for sterilization processes along with its own sterilants and disinfectants. The company’s products are essential for validating that sterilization and HLD cycles have been effective.

Innovation Focus:

  • Leading provider of biological and chemical indicators for sterilization assurance

  • Research into new antimicrobial technologies and rapid-read biological indicators

Get Full Report Here:
Sterilants and High Level Disinfectants Market – View in Detailed Research Report


🔬 Outlook: The Future of Sterilants and High-Level Disinfectants Is Smarter and More Integrated

The sterilants and high-level disinfectants market is experiencing a technological evolution. While chemical efficacy remains the cornerstone, the industry is rapidly adopting automation, connectivity, and data analytics to enhance traceability, reduce human error, and ensure unwavering compliance with stringent standards.

📈 Key Trends Shaping the Market:

  • Rising adoption of Automated Endoscope Reprocessors (AERs) and track-and-trace systems

  • Increasing regulatory scrutiny on duodenoscope and complex device reprocessing

  • Development of greener, more sustainable disinfectant chemistries with reduced environmental impact

  • Integration of sterilization monitoring data with hospital Electronic Medical Record (EMR) systems

Get Full Report Here:
Sterilants and High Level Disinfectants Market – View in Detailed Research Report

The companies listed above are not merely supplying chemicals—they are providing the essential safeguards for modern healthcare, enabling millions of safe medical procedures every day.