The Global Silk Protein Market was valued at USD 478.3 Million in 2023 and is projected to reach USD 780.9 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 7.2% during the forecast period (2024–2030). This robust growth is fueled by surging demand for natural and sustainable ingredients in personal care products, advancements in biotechnology, and the expanding applications of silk protein in pharmaceuticals and nutraceuticals.

As the beauty and wellness industries pivot towards high-performance, eco-friendly bio-actives, the spotlight intensifies on the biotechnology firms and ingredient suppliers pioneering silk protein innovation. In this blog, we profile the Top 10 Companies in the Silk Protein Industry—a blend of established biochemical leaders and cutting-edge biotech startups shaping the future of this dynamic market.

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🔟 1. Evolved by Nature (Previously Silk Inc.)

Headquarters: Boston, Massachusetts, USA
Key Offering: Activated Silk™ protein technology

Evolved by Nature is a trailblazer in the silk protein sector, leveraging its proprietary Activated Silk™ platform. This technology transforms pure silk into a versatile, liquid protein that is readily incorporated into a wide array of formulations, from luxury skincare to advanced medical dressings, offering superior moisturization and biocompatibility.

Sustainability & Innovation Initiatives:

• Closed-loop silk sourcing and production process

• Partnerships with major beauty and healthcare brands

• Focus on replacing synthetic polymers with natural silk proteins

Download FREE Sample Report: Silk Protein Market – View in Detailed Research Report

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9️⃣ 2. Kraig Biocraft Laboratories, Inc. (KBLB)

Headquarters: Lansing, Michigan, USA
Key Offering: Recombinant spider silk proteins (Dragon Silk®, Monster Silk®)

Kraig Biocraft Laboratories is a publicly traded leader in genetic engineering, specializing in the production of recombinant spider silk. Their proprietary silkworms are engineered to produce high-performance silk fibers with exceptional strength and elasticity, targeting applications far beyond cosmetics, including textiles, medical devices, and ballistic protection.

Sustainability & Innovation Initiatives:

• Pioneering transgenic silkworm technology

• Strategic contracts with the US Department of Defense and textile manufacturers

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8️⃣ 3. AMSilk GmbH

Headquarters: Planegg, Germany
Key Offering: Bio-based silk proteins (Silkbeads®, Slik™)

AMSilk is a leading European biopolymers company, known for its engineered silk proteins produced through a sustainable, plant-based fermentation process. Their ingredients are designed for skincare and haircare, providing a smooth, silky feel, improved product stability, and enhanced skin adhesion.

Sustainability & Innovation Initiatives:

• 100% animal-free, vegan silk protein production

• Collaboration with L’Oréal and other cosmetic giants

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7️⃣ 4. Bolt Threads

Headquarters: Emeryville, California, USA
Key Offering: Microsilk™, B-silk™ protein

Bolt Threads has gained significant recognition for its biomimetic approach, creating silk proteins inspired by spider silk. Their Microsilk™ is designed for performance textiles, while B-silk™ is optimized for skincare, offering film-forming and moisturizing properties without the stickiness of traditional ingredients.

Sustainability & Innovation Initiatives:

• Focus on scaling biofabrication for circular economy

• Partnerships in fashion (Stella McCartney, Adidas) and cosmetics

Download FREE Sample Report: Silk Protein Market – View in Detailed Research Report

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6️⃣ 5. Huzhou Xintiansi Bio-tech Co., Ltd.

Headquarters: Huzhou, Zhejiang, China
Key Offering: Hydrolyzed silk protein, Silk peptide, Silk amino acid

Huzhou Xintiansi Bio-tech is a major global supplier of hydrolyzed silk proteins, catering primarily to the personal care industry. With extensive manufacturing capabilities in China, the company provides a wide range of silk-derived ingredients known for their hair and skin conditioning benefits.

Sustainability & Innovation Initiatives:

• Large-scale, cost-effective production for mass-market cosmetics

• Continuous R&D to improve protein purity and functionality

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5️⃣ 6. Huzhou Aotesi Biochemical

Headquarters: Huzhou, Zhejiang, China
Key Offering: Silk protein powder, Silk peptide for cosmetics

Huzhou Aotesi Biochemical is another key Chinese player with a strong foothold in the silk protein ingredient market. The company specializes in extracting and processing silk proteins into various forms suitable for lotions, creams, shampoos, and serums, serving a global client base.

Sustainability & Innovation Initiatives:

• Vertical integration from raw silk sourcing to finished ingredient production

• Focus on meeting international quality and safety standards

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4️⃣ 7. SilkTech Biopharmaceuticals

Headquarters: Englewood, Colorado, USA
Key Offering: S^i™ Silk-based biomaterials for healthcare

SilkTech Biopharmaceuticals focuses on the high-value medical and pharmaceutical applications of silk protein. Their S^i™ platform technology utilizes silk fibroin to create advanced biomaterials for drug delivery, tissue engineering, and medical devices, leveraging silk’s innate biocompatibility and tunable degradation.

Sustainability & Innovation Initiatives:

• R&D focused on FDA-approved medical products

• Exploring silk’s potential in regenerative medicine

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3️⃣ 8. Universal Preserv-A-Chem Inc.

Headquarters: Carteret, New Jersey, USA
Key Offering: Distributor of hydrolyzed silk protein and other botanical extracts

Universal Preserv-A-Chem (UPI) is a leading distributor and supplier of specialty ingredients to the personal care industry. While not a primary manufacturer, UPI plays a crucial role in the supply chain, providing formulators with easy access to high-quality silk proteins from various producers alongside complementary ingredients.

Sustainability & Innovation Initiatives:

• Global supply chain logistics for natural ingredients

• Technical support for formulators integrating silk proteins

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2️⃣ 9. SUBONEYO CHEMICALS AND PHARMACEUTICALS PRIVATE LIMITED

Headquarters: Kolkata, West Bengal, India
Key Offering: Silk protein powder for cosmetics and nutraceuticals

SUBONEYO is a significant supplier of natural ingredients from the Indian subcontinent. The company provides silk protein derived from traditional sericulture, tapping into India’s rich silk production heritage to serve both domestic and international markets in personal care and health sectors.

Sustainability & Innovation Initiatives:

• Sourcing from sustainable Indian sericulture practices

• Expanding product portfolio to include value-added silk derivatives

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1️⃣ 10. Proteina

Headquarters: (Information varies; often a regional supplier)
Key Offering: Broad range of silk protein hydrolysates

Proteina, representing a category of specialized ingredient suppliers, focuses on providing accessible and effective silk protein solutions. These companies are essential for smaller to mid-sized brands seeking to incorporate the benefits of silk—such as moisture retention, film-forming, and strengthening properties—into their formulations at competitive prices.

Sustainability & Innovation Initiatives:

• Bridging the gap between large-scale producers and niche brands

• Providing customizable silk protein blends

Get Full Report Here: Silk Protein Market – View in Detailed Research Report

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🌍 Outlook: The Future of Silk Protein Is High-Tech and Holistic

The silk protein market is experiencing a profound transformation. While traditional hydrolyzed proteins remain a staple, the industry is channeling significant investment into bio-engineered silk, advanced delivery systems, and novel applications that stretch from topical creams to internal medical implants.

📈 Key Trends Shaping the Market:

• Rise of recombinant DNA technology for producing novel silk proteins with customized properties

• Growing consumer demand for clean, vegan, and sustainably sourced beauty ingredients

• Expansion into high-growth therapeutic areas like wound healing and controlled drug release

• Increased merger and acquisition activity as large chemical conglomerates seek to acquire biotech innovation

Get Full Report Here: Silk Protein Market – View in Detailed Research Report

The companies listed above are not only supplying a versatile ingredient—they are actively engineering the future of biomaterials for a more sustainable and effective world.