The Global Pyrroloquinoline Quinone (PQQ) Market was valued at USD 188.7 Million in 2024 and is projected to reach USD 325.4 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 9.5% during the forecast period (2024–2030). This robust growth is fueled by rising consumer awareness of cognitive health, the expanding nutraceutical and cosmetic industries, and increasing clinical research validating PQQ’s antioxidant and neuroprotective benefits.

As the demand for advanced dietary supplements and functional ingredients surges, key manufacturers are scaling production, enhancing purity levels, and exploring new applications. In this blog, we profile the Top 10 Companies in the Pyrroloquinoline Quinone Industry—pioneers in biotechnology and chemical synthesis who are shaping the future of this vital nutrient.

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🔟 1. MITSUBISHI GAS CHEMICAL COMPANY, INC.

Headquarters: Tokyo, Japan
Key Offering: High-Purity PQQ (BioPQQ™)

Mitsubishi Gas Chemical is a global leader in the industrial production of Pyrroloquinoline Quinone. The company’s proprietary BioPQQ™ is one of the most widely used and researched forms of PQQ, recognized for its high purity and stability. They supply major nutraceutical brands worldwide.

Innovation and Quality Initiatives:

• Pioneer in large-scale, cGMP-certified PQQ production

• Significant investment in R&D for new PQQ applications

• Commitment to sustainable and efficient manufacturing processes

Download FREE Sample Report: Pyrroloquinoline Quinone Market – View in Detailed Research Report

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9️⃣ 2. Global Biologicals Co., Ltd

Headquarters: Nantong, China
Key Offering: PQQ Disodium Salt (Purity 98%-99.5%)

Global Biologicals Co., Ltd is a leading Chinese manufacturer specializing in high-quality active pharmaceutical ingredients (APIs) and nutritional compounds. The company has established a strong position in the PQQ market with its cost-effective and scalable production capabilities.

Innovation and Quality Initiatives:

• Focus on producing PQQ with varying purity grades for different applications

• Expanding distribution network across North America and Europe

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8️⃣ 3. Fuzhou Contay Biotechnology Co., Ltd.

Headquarters: Fuzhou, China
Key Offering: PQQ Raw Material, PQQ Disodium Salt

Fuzhou Contay Biotechnology is a key player in the synthesis of fine chemicals and nutritional ingredients. The company has developed advanced fermentation and purification technologies to produce high-yield PQQ, catering to the growing global demand.

Innovation and Quality Initiatives:

• Investment in advanced bioreactor technology for efficient production

• Strong focus on quality control and regulatory compliance for international markets

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7️⃣ 4. World-Way Biotech Inc

Headquarters: Xi’an, China
Key Offering: Pyrroloquinoline Quinone (PQQ) for Nutraceuticals

World-Way Biotech specializes in the research, development, and manufacturing of plant extracts and bioactive compounds. The company has emerged as a significant supplier of PQQ, particularly for the dietary supplement industry, with a commitment to natural and sustainable sourcing.

Innovation and Quality Initiatives:

• Development of eco-friendly extraction and synthesis methods

• Strategic partnerships with supplement formulators and brands

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6️⃣ 5. Accenture

Headquarters: Dublin, Ireland
Key Offering: Consulting and Supply Chain Solutions for PQQ Market

While not a manufacturer, Accenture plays a crucial role in the PQQ ecosystem through its consulting services. The firm advises major chemical and life sciences companies on market strategy, digital transformation of supply chains, and optimizing manufacturing and distribution for ingredients like PQQ.

Innovation and Quality Initiatives:

• Digital supply chain modeling for ingredient traceability

• Market intelligence and growth strategy for client companies

Download FREE Sample Report: Pyrroloquinoline Quinone Market – View in Detailed Research Report

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5️⃣ 6. Hangzhou Asiaware Biomedical Technology Co., Ltd.

Headquarters: Hangzhou, China
Key Offering: Pharmaceutical and Nutraceutical Grade PQQ

Hangzhou Asiaware Biomedical Technology focuses on the R&D and production of high-purity biochemical products. The company supplies PQQ to pharmaceutical companies for research and development, as well as to nutraceutical companies for finished products.

Innovation and Quality Initiatives:

• Specialization in high-purity, research-grade PQQ

• Collaborations with academic institutions for clinical research

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4️⃣ 7. HNova Technology Co., Ltd.

Headquarters: Shanghai, China
Key Offering: PQQ Ingredients for Cosmetic and Health Products

HNova Technology is an integrated company engaged in the development and sales of specialty chemicals. It has developed a presence in the PQQ market by supplying ingredients tailored for cosmetic formulations, leveraging PQQ’s antioxidant properties for skincare applications.

Innovation and Quality Initiatives:

• Application-specific development of PQQ for anti-aging cosmetics

• Focus on sustainable and green chemistry principles

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3️⃣ 8. Wuxi Further Biotechnology Co., Ltd.

Headquarters: Wuxi, China
Key Offering: PQQ and other Nootropic Ingredients

Wujiang Further Biotechnology specializes in the production of nootropic and cognitive health ingredients. The company produces PQQ as part of its broader portfolio aimed at the brain health supplement market, often combining it with other compounds like CoQ10.

Innovation and Quality Initiatives:

• Development of synergistic ingredient blends featuring PQQ

• Investment in clinical studies to substantiate health claims

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2️⃣ 9. Zhejiang Silver Elephant Bioengineering Co., Ltd.

Headquarters: Zhejiang, China
Key Offering: Fermentation-derived PQQ

Zhejiang Silver Elephant Bioengineering utilizes advanced microbial fermentation technology to produce a range of bioactive compounds. Their expertise in fermentation makes them a reliable supplier of bio-identical PQQ, which is increasingly preferred in the natural products industry.

Innovation and Quality Initiatives:

• Expertise in large-scale microbial fermentation processes

• Focus on producing non-GMO and allergen-free ingredients

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1️⃣ 10. Shaanxi Zebrago Industrial Co., Ltd.

Headquarters: Shaanxi, China
Key Offering: PQQ Powder for Export Markets

Shaanxi Zebrago Industrial is a supplier and exporter of pharmaceutical intermediates and nutritional ingredients. The company has built a strong reputation for supplying quality PQQ to international markets, supported by rigorous testing and competitive pricing.

Innovation and Quality Initiatives:

• Strict quality control protocols meeting international standards

• Efficient logistics and supply chain management for global clients

Get Full Report Here: Pyrroloquinoline Quinone Market – View in Detailed Research Report

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🌍 Outlook: The Future of Pyrroloquinoline Quinone Is Brighter and Broader

The Pyrroloquinoline Quinone market is experiencing a significant transformation. While its primary application remains in dietary supplements, research is continuously uncovering new potential uses, driving innovation and expansion across multiple industries.

📈 Key Trends Shaping the Market:

• Rising consumer demand for brain health and nootropic supplements

• Expansion into cosmetic applications for anti-aging and skin vitality

• Increasing clinical research supporting PQQ’s benefits for mitochondrial health

• Growing preference for fermented, bio-identical PQQ over synthetic alternatives

Get Full Report Here: Pyrroloquinoline Quinone Market – View in Detailed Research Report

The companies listed above are not only supplying a critical nutrient—they’re pioneering the scientific advancement of human health and wellness.