The Global Vitamin K2 MK-7 Market was valued at USD 135.8 Million in 2024 and is projected to reach USD 225.3 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 8.7% during the forecast period (2024–2030). This robust growth is primarily driven by increasing consumer awareness of cardiovascular and bone health, the rising prevalence of osteoporosis, and the expanding application of vitamin K2 MK-7 in fortified foods, dietary supplements, and pharmaceuticals.

As the nutraceutical and pharmaceutical industries pivot toward proactive wellness solutions, the focus intensifies on the key manufacturers innovating in purity, bioavailability, and sustainable production of this essential nutrient. In this blog, we profile the Top 10 Companies in the Vitamin K2 MK-7 Industry—a group of biotechnology firms, ingredient suppliers, and pharmaceutical giants steering the future of global health supplementation.

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🔟 1. Kappa Bioscience AS

Headquarters: Oslo, Norway
Key Offering: K2Vital® Vitamin K2 MK-7 (all-trans menaquinone-7)

Kappa Bioscience is a globally recognized leader and pioneer in the production of highly stable and bioavailable Vitamin K2 MK-7. The company’s proprietary K2Vital® brand is the gold standard in the industry, known for its high purity (over 99% all-trans form) and superior stability in various applications, from tablets to functional foods. They supply major brands in the dietary supplement and food fortification sectors worldwide.

Innovation and Quality Initiatives:

• Patented fermentation and purification technology ensuring >99% all-trans MK-7
• Extensive clinical research supporting the efficacy of K2Vital®
• Focus on GRAS (Generally Recognized as Safe) and Novel Food approvals in key markets

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9️⃣ 2. NattoPharma ASA (Part of Gnosis by Lesaffre)

Headquarters: Oslo, Norway (now integrated into Gnosis by Lesaffre)
Key Offering: MenaQ7® Vitamin K2 as MK-7

NattoPharma was a foundational company in the Vitamin K2 MK-7 market, renowned for its MenaQ7® brand, which boasts the most extensive portfolio of human clinical studies demonstrating its benefits for bone and cardiovascular health. Following its acquisition by Gnosis by Lesaffre, the combined entity has solidified its position as a dominant force, leveraging deep scientific backing and global distribution networks.

Innovation and Quality Initiatives:

• Pioneering clinical research establishing the health benefits of MK-7
• Integration with Gnosis’s fermentation expertise for enhanced production scale
• Strong focus on patent-protected, scientifically-validated ingredients

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8️⃣ 3. Gnosis by Lesaffre

Headquarters: Milan, Italy (Global HQ)
Key Offering: MenaQ7® Vitamin K2 (MK-7), other bioactive nutrients via fermentation

Gnosis by Lesaffre utilizes the power of yeast and bacterial fermentation to produce a range of bioactive ingredients, including its flagship Vitamin K2 MK-7. The acquisition of NattoPharma has created a synergistic powerhouse, combining Gnosis’s industrial fermentation capabilities with the strong scientific and brand legacy of MenaQ7®. They serve the pharmaceutical, nutraceutical, and functional food industries globally.

Innovation and Quality Initiatives:

• World-class fermentation technology platform
• Commitment to non-GMO, allergen-free production processes
• Strategic expansion of production capacity to meet growing global demand

Download FREE Sample Report: Global Vitamin K2 MK-7 Market – View in Detailed Research Report

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7️⃣ 4. Royal DSM N.V.

Headquarters: Heerlen, Netherlands
Key Offering: Multiple vitamin and nutrient solutions, including Vitamin K formulations

DSM is a global science-based company active in health, nutrition, and bioscience. While offering a broad portfolio of vitamins, DSM has a significant presence in the Vitamin K market. Their expertise in human nutrition and health allows them to provide tailored solutions for dietary supplements and fortified foods, leveraging strong R&D and regulatory support for their ingredients worldwide.

Innovation and Quality Initiatives:

• Extensive R&D investments in nutritional science
• Focus on sustainability and reducing environmental footprint of production
• Global supply chain ensuring consistent quality and availability

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6️⃣ 5. Viridis BioPharma Pvt. Ltd.

Headquarters: Mumbai, India
Key Offering: Pharmaceutical-grade Vitamin K2 (MK-7) and other nutraceutical ingredients

Viridis BioPharma is a leading Indian manufacturer specializing in high-purity active pharmaceutical ingredients (APIs) and nutraceuticals. The company has carved a niche in the Vitamin K2 MK-7 market by offering cost-effective, high-quality ingredients that meet stringent international standards, catering to both domestic and international markets.

Innovation and Quality Initiatives:

• State-of-the-art manufacturing facilities compliant with GMP (Good Manufacturing Practices)
• Strong focus on research to improve yield and purity of MK-7
• Strategic positioning to serve the rapidly growing Asia-Pacific market

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5️⃣ 6. Frutarom Health (Part of International Flavors & Fragrances Inc., IFF)

Headquarters: Haifa, Israel (Now part of IFF)
Key Offering: Nutritional ingredients, including vitamins and botanical extracts

Frutarom Health, now operating under IFF’s Health & Biosciences division, has a history of providing innovative health and wellness ingredients. While its portfolio is diverse, its capabilities in sourcing and developing high-quality nutrients position it as a significant player in the broader vitamin market, with the potential to influence the K2 MK-7 segment through its extensive customer base and application expertise.

Innovation and Quality Initiatives:

• Integration into IFF provides vast R&D resources and global reach
• Expertise in creating synergistic blends of vitamins and botanicals
• Commitment to sustainability and natural sourcing where applicable

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4️⃣ 7. DuPont Nutrition & Biosciences (Now part of IFF)

Headquarters: Wilmington, Delaware, USA (Now part of IFF)
Key Offering: Broad portfolio of food ingredients, enzymes, and probiotics

DuPont Nutrition & Biosciences, following its merger with IFF, brings immense scale and application knowledge to the health and nutrition space. Their expertise in fermentation science—critical for probiotic and enzyme production—provides a strong technological foundation relevant to the biosynthesis of Vitamin K2 MK-7, making them an important entity in the supply chain for fortified foods and supplements.

Innovation and Quality Initiatives:

• World-leading capabilities in microbial fermentation technology
• Strong application support for incorporating nutrients into complex food matrices
• Focus on science-backed solutions for health and wellness

Download FREE Sample Report: Global Vitamin K2 MK-7 Market – View in Detailed Research Report

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3️⃣ 8. GeneFerm Biotechnology Co., Ltd.

Headquarters: Taoyuan City, Taiwan
Key Offering: Fermentation-derived ingredients, including Vitamin K2

GeneFerm Biotechnology is a specialized Taiwanese company focused on the research, development, and manufacturing of fine chemicals and active pharmaceutical ingredients through microbial fermentation. They are a key Asian manufacturer of Vitamin K2, including the MK-7 form, supplying to regional and global markets with a focus on quality and competitive pricing.

Innovation and Quality Initiatives:

• Dedicated R&D in strain improvement and fermentation optimization
• cGMP compliant manufacturing practices
• Strategic focus on the high-growth nutraceutical sector in Asia

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2️⃣ 9. Shanghai Reson Biotech Co., Ltd.

Headquarters: Shanghai, China
Key Offering: Vitamin K2 (MK-7) powders and oils, other vitamin ingredients

Shanghai Reson Biotech is a prominent Chinese manufacturer and supplier of vitamin ingredients. The company produces Vitamin K2 MK-7 and serves a global clientele in the dietary supplement and pharmaceutical industries. Its strength lies in scalable production and cost-efficiency, making it a significant supplier, particularly in the price-sensitive segments of the market.

Innovation and Quality Initiatives:

• Continuous improvement of production processes for higher purity and yield
• Adherence to international quality standards for export markets
• Active participation in the expanding Chinese domestic health market

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1️⃣ 10. Kyowa Hakko Bio Co., Ltd.

Headquarters: Tokyo, Japan
Key Offering: “Kyowa Quality” amino acids, nucleic acids, and vitamins

Kyowa Hakko Bio, a member of the Kirin Group, is a world-renowned Japanese biotech company with a long history of excellence in fermentation. While renowned for its amino acids, its expertise extends to the production of high-purity vitamins and other bioactive compounds. The company’s reputation for “Kyowa Quality” makes it a trusted supplier for pharmaceutical and high-end supplement manufacturers globally.

Innovation and Quality Initiatives:

• Leading-edge fermentation and biocatalyst technology
• Stringent quality control systems ensuring product safety and efficacy
• Strong commitment to research and development in life sciences

Get Full Report Here: Global Vitamin K2 MK-7 Market – View in Detailed Research Report

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🔬 Outlook: The Future of Vitamin K2 MK-7 Lies in Science and Accessibility

The Vitamin K2 MK-7 market is experiencing a significant evolution. While the ingredient is well-established in the premium supplement sector, the future points toward broader inclusion in everyday foods and personalized nutrition, backed by robust scientific validation.

📈 Key Trends Shaping the Market:

• Growing body of clinical evidence linking MK-7 to cardiovascular and cognitive health, beyond bone health.
• Increasing demand for clean-label and plant-based (fermentation-derived) ingredients.
• Rising geriatric population and awareness of osteoporosis driving preventative healthcare.
• Expansion of food fortification programs in emerging economies.

Get Full Report Here: Global Vitamin K2 MK-7 Market – View in Detailed Research Report

The companies profiled above are not merely suppliers of a nutrient—they are active participants in a global health revolution, translating scientific discovery into tangible wellness solutions for millions.