Top 10 Companies in the Heparin Calcium API Industry (2023-2028): Market Leaders Powering Global Anticoagulant Therapeutics

In Business Insights
November 09, 2025


The Global Heparin Calcium API Market is projected to experience significant growth from 2023 to 2028, driven by the rising global demand for anticoagulant therapies and the increasing prevalence of thromboembolic disorders. Based on newly published research, the market’s expansion is underpinned by technological advancements in heparin manufacturing, stringent quality control standards, and the critical role of these active pharmaceutical ingredients in producing life-saving injectable anticoagulants. As the pharmaceutical industry continues to prioritize the development and reliable supply of essential blood-thinning medications, the key manufacturers of Heparin Calcium API are at the forefront of ensuring global health security.

This essential anticoagulant market is characterized by high regulatory scrutiny, complex manufacturing processes, and a concentrated vendor landscape dominated by specialized producers. In this blog, we profile the Top 10 Companies in the Heparin Calcium API Industry—a mix of established pharmaceutical giants and specialized bio-pharmaceutical firms that are shaping the future of anticoagulant therapy worldwide.


🔟 1. CSBIO

Headquarters: Hangzhou, China
Key Offering: Heparin Sodium API, Heparin Calcium API

CSBIO is a leading global supplier of heparin APIs, with extensive experience in the extraction, purification, and manufacturing of heparin products. The company operates state-of-the-art facilities compliant with international regulatory standards including FDA and EMA, serving pharmaceutical customers worldwide.

Quality & Innovation Initiatives:

  • Advanced purification technologies ensuring high product purity
  • Rigorous quality control systems throughout the supply chain
  • Strategic partnerships with global pharmaceutical manufacturers

Download FREE Sample Report: 2023-2028 Global and Regional Heparin Calcium API Industry Status and Prospects Professional Market – View in Detailed Research Report


9️⃣ 2. Dongcheng Pharmaceutical

Headquarters: Dongying, Shandong, China
Key Offering: Heparin Calcium API, Heparin Sodium API

Dongcheng Pharmaceutical has established itself as a major player in the heparin API market with comprehensive manufacturing capabilities. The company’s vertically integrated operations span from raw material sourcing to finished API production, ensuring supply chain control and quality consistency.

Quality & Innovation Initiatives:

  • Vertical integration for enhanced supply chain security
  • Continuous process optimization for improved yield and purity
  • Expansion of production capacity to meet growing global demand

8️⃣ 3. Cisen Pharmaceutical

Headquarters: Jining, Shandong, China
Key Offering: Heparin Calcium API, Pharmaceutical Intermediates

Cisen Pharmaceutical specializes in the production of high-quality Heparin Calcium API with a focus on meeting the stringent requirements of international markets. The company’s expertise in complex carbohydrate chemistry positions it as a reliable supplier to the global pharmaceutical industry.

Quality & Innovation Initiatives:

  • Implementation of advanced analytical testing methodologies
  • Focus on regulatory compliance across multiple international markets
  • Investment in research for heparin derivative development

7️⃣ 4. Qianhong Biopharma

Headquarters: Suzhou, Jiangsu, China
Key Offering: Heparin Calcium API, Low Molecular Weight Heparins

Qianhong Biopharma is recognized for its technological expertise in heparin API manufacturing and its commitment to product quality. The company has developed sophisticated purification processes that ensure consistent API quality for pharmaceutical formulations.

Quality & Innovation Initiatives:

  • Proprietary purification technologies for enhanced product safety
  • Strategic focus on high-purity heparin segments
  • Collaboration with academic institutions for process innovation

6️⃣ 5. Nanjing King-friend

Headquarters: Nanjing, Jiangsu, China
Key Offering: Heparin Calcium API, Heparin Sodium USP

Nanjing King-friend has built a strong reputation as a quality-focused manufacturer of heparin APIs. The company’s manufacturing facilities adhere to cGMP standards, and its products are supplied to pharmaceutical companies across multiple continents.

Quality & Innovation Initiatives:

  • Comprehensive quality management systems
  • Diversified product portfolio serving various market needs
  • Strategic expansion of international market presence

5️⃣ 6. Yino Pharma

Headquarters: Lianyungang, Jiangsu, China
Key Offering: Heparin Calcium API, Pharmaceutical Raw Materials

Yino Pharma specializes in the production of Heparin Calcium API with a focus on consistency and reliability. The company’s manufacturing processes are designed to meet the evolving regulatory requirements of global health authorities.

Quality & Innovation Initiatives:

  • Robust supplier qualification and audit programs
  • Continuous improvement in manufacturing efficiency
  • Investment in quality control infrastructure

Download FREE Sample Report: 2023-2028 Global and Regional Heparin Calcium API Industry Status and Prospects Professional Market – View in Detailed Research Report


4️⃣ 7. Tianjin Chasesun Pharmaceutical

Headquarters: Tianjin, China
Key Offering: Heparin Calcium API, Finished Dosage Forms

Tianjin Chasesun Pharmaceutical operates as an integrated pharmaceutical company with capabilities spanning from API manufacturing to finished drug products. This vertical integration provides the company with unique insights into the entire heparin product value chain.

Quality & Innovation Initiatives:

  • Integrated approach from API to finished product
  • Focus on therapeutic consistency and batch-to-batch uniformity
  • Expansion of regulatory approvals in emerging markets

3️⃣ 8. Sheelian Pharmaceutical

Headquarters: Xinxiang, Henan, China
Key Offering: Heparin Calcium API, Specialty Pharmaceuticals

Sheelian Pharmaceutical has established a strong position in the heparin API market through its commitment to quality and customer service. The company’s manufacturing expertise enables it to produce heparin APIs that meet the specific requirements of diverse pharmaceutical applications.

Quality & Innovation Initiatives:

  • Customer-centric approach to product development
  • Implementation of lean manufacturing principles
  • Strategic partnerships with global distribution networks

2️⃣ 9. Erye Pharmaceutical

Headquarters: Beijing, China
Key Offering: Heparin Calcium API, Antibiotic APIs

Erye Pharmaceutical brings extensive pharmaceutical manufacturing experience to the heparin API market. The company’s diversified product portfolio and established quality systems position it as a reliable supplier in the global pharmaceutical ingredients market.

Quality & Innovation Initiatives:

  • Leveraging expertise from multiple API manufacturing segments
  • Investment in modern manufacturing infrastructure
  • Focus on sustainable and environmentally responsible production

1️⃣ 10. Bioibérica

Headquarters: Barcelona, Spain
Key Offering: Heparin Calcium API, Specialty Biopharmaceuticals

Bioibérica stands as a prominent European manufacturer of Heparin Calcium API with a strong focus on research and development. The company’s expertise in glycosaminoglycans and commitment to innovation has established it as a key player in the global heparin market.

Quality & Innovation Initiatives:

  • Pioneering research in heparin-based therapeutics
  • Stringent quality control aligned with European regulatory standards
  • Development of novel heparin derivatives and applications

Get Full Report Here: 2023-2028 Global and Regional Heparin Calcium API Industry Status and Prospects Professional Market – View in Detailed Research Report


🌍 Outlook: The Future of Heparin Calcium API Market

The Heparin Calcium API market is undergoing significant transformation driven by evolving regulatory landscapes, technological advancements, and growing therapeutic applications. While traditional markets continue to drive demand, emerging applications and geographic markets present new growth opportunities for industry participants.

📈 Key Trends Shaping the Market:

  • Increasing regulatory scrutiny and quality requirements across global markets
  • Technological advancements in purification and analytical methods
  • Growing demand for anticoagulant therapies in aging populations
  • Expansion of heparin applications beyond traditional anticoagulation

Get Full Report Here: 2023-2028 Global and Regional Heparin Calcium API Industry Status and Prospects Professional Market – View in Detailed Research Report

The companies profiled above represent the cornerstone of the global heparin supply chain, ensuring the continued availability of essential anticoagulant therapies that save lives and improve patient outcomes worldwide.