The Global 2-Methyltetrahydrofuran (2-MeTHF) Market was valued at approximately USD 280 Million in 2024 and is projected to reach USD 420 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of around 6.8% during the forecast period (2024–2030). This robust growth is primarily driven by the chemical’s expanding role as a green, bio-based solvent in pharmaceuticals, agrochemicals, and polymer production, replacing more hazardous options like tetrahydrofuran (THF) and dichloromethane.

As industries worldwide pivot towards sustainable and safer chemical processes, the demand for high-purity 2-MeTHF is surging. The spotlight is on the key producers and suppliers who are scaling up production, ensuring stringent quality control, and driving innovation in its applications. In this blog, we profile the Top 10 Companies in the 2-Methyltetrahydrofuran Industry—a mix of global chemical giants, specialized manufacturers, and distributors shaping the future of this versatile solvent.

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🔟 1. Merck KGaA (Merck Millipore)

Headquarters: Darmstadt, Germany
Key Offering: High-Purity 2-MeTHF (Analytical & Laboratory Reagent Grades)

Merck KGaA, operating through its Millipore brand, is a leading global supplier of life science tools and high-purity performance materials. The company offers 2-Methyltetrahydrofuran that meets the stringent requirements of pharmaceutical R&D and quality control laboratories worldwide.

Innovation & Quality Initiatives:

• Supply of ultra-high purity solvents for critical pharmaceutical syntheses

• Extensive documentation and regulatory support (e.g., USP, EP, JP)

• Commitment to sustainable chemical production and green chemistry principles

Download FREE Sample Report: 2-Methyltetrahydrofuran Market – View in Detailed Research Report

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9️⃣ 2. Honeywell International Inc.

Headquarters: Charlotte, North Carolina, USA
Key Offering: Honeywell 2-MeTHF (Technical & Commercial Grades)

Honeywell is a major diversified technology and manufacturing leader, supplying high-performance chemicals to a broad industrial base. Their 2-MeTHF is used extensively as a solvent in resins, adhesives, and as a reaction medium in chemical manufacturing.

Innovation & Quality Initiatives:

• Production of consistent, high-quality solvent grades for industrial applications

• Robust global supply chain and logistics network

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8️⃣ 3. Monument Chemical

Headquarters: Indianapolis, Indiana, USA
Key Offering: 2-Methyltetrahydrofuran (Various Purity Grades)

Monument Chemical is a key North American manufacturer of specialty and performance chemicals. The company specializes in producing 2-MeTHF for use in pharmaceuticals, electronics, and specialty polymer applications, emphasizing reliable supply and product consistency.

Innovation & Quality Initiatives:

• Strategic focus on niche chemical intermediates

• Custom synthesis and purification services for specific client requirements

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7️⃣ 4. Tedia Company, Inc.

Headquarters: Fairfield, Ohio, USA
Key Offering: High-Purity Solvents including 2-MeTHF

Tedia is a renowned global manufacturer of high-purity solvents for chromatography, spectroscopy, and organic synthesis. The company supplies 2-Methyltetrahydrofuran that is essential for analytical laboratories and fine chemical production.

Innovation & Quality Initiatives:

• Specialization in HPLC and GC grade solvents

• Stringent quality control ensuring low water content and impurities

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6️⃣ 5. Oakwood Chemical

Headquarters: Estill, South Carolina, USA
Key Offering: Research-grade 2-MeTHF and custom chemical synthesis

Oakwood Chemical is a leading supplier of fine chemicals, research chemicals, and pharmaceutical intermediates. They provide high-quality 2-MeTHF primarily to the academic, R&D, and pharmaceutical sectors.

Innovation & Quality Initiatives:

• Extensive catalog of over 40,000 chemical products

• Focus on serving the research and development community

Download FREE Sample Report: 2-Methyltetrahydrofuran Market – View in Detailed Research Report

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5️⃣ 6. Novasol Chemicals

Headquarters: Hamburg, Germany
Key Offering: 2-MeTHF and other specialty solvents

Novasol Chemicals is a European supplier specializing in high-purity solvents and chemical intermediates. The company distributes 2-Methyltetrahydrofuran to various industries, with a strong focus on the European pharmaceutical and chemical manufacturing markets.

Innovation & Quality Initiatives:

• Distribution partnerships with leading chemical producers

• Compliance with REACH and other European chemical regulations

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4️⃣ 7. SynQuest Labs, Inc.

Headquarters: Alachua, Florida, USA
Key Offering: Specialty chemicals and custom synthesis, including 2-MeTHF

SynQuest Labs is a manufacturer and supplier of high-purity chemicals, catalysts, and specialty gases. The company provides 2-Methyltetrahydrofuran for research institutions and industrial clients engaged in advanced material synthesis.

Innovation & Quality Initiatives:

• Expertise in organometallic chemistry and catalyst systems

• Custom chemical synthesis services for niche applications

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3️⃣ 8. Scientific Laboratory Supplies Ltd (SLS)

Headquarters: Nottingham, United Kingdom
Key Offering: Laboratory chemicals and consumables, including 2-MeTHF

SLS is a major distributor of scientific products and laboratory chemicals across the UK and Ireland. They supply 2-Methyltetrahydrofuran primarily to academic, research, and quality control laboratories.

Innovation & Quality Initiatives:

• Comprehensive distribution network for laboratory supplies

• Strong relationships with educational and research institutions

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2️⃣ 9. Fluorochem Ltd.

Headquarters: Old Glossop, United Kingdom
Key Offering: Fine chemicals, building blocks, and solvents like 2-MeTHF

Fluorochem is a leading supplier of fine chemicals, biochemicals, and research compounds. The company provides high-quality 2-MeTHF to the pharmaceutical, agrochemical, and material science sectors.

Innovation & Quality Initiatives:

• Specialization in fluorinated compounds and chiral intermediates

• GMP and ISO 9001 certified facilities for quality assurance

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1️⃣ 10. Glentham Life Sciences

Headquarters: Corsham, United Kingdom
Key Offering: Research chemicals, APIs, and solvents including 2-MeTHF

Glentham Life Sciences is a global supplier of fine chemicals, raw materials, and research compounds. They distribute 2-Methyltetrahydrofuran to the life sciences, research, and industrial chemistry markets, emphasizing product purity and reliable delivery.

Innovation & Quality Initiatives:

• Broad portfolio of over 6,000 chemical products

• Strategic global sourcing and distribution capabilities

Get Full Report Here: 2-Methyltetrahydrofuran Market – View in Detailed Research Report

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🌍 Outlook: The Future of 2-Methyltetrahydrofuran Is Sustainable and High-Performance

The 2-Methyltetrahydrofuran market is undergoing a significant transformation. As a solvent derived from renewable resources like furfural, it is increasingly favored over petrochemical-based alternatives due to its superior environmental profile and excellent solvent properties. The industry is investing in advanced purification technologies and bio-based production pathways to meet the growing demand from the pharmaceutical and green chemistry sectors.

📈 Key Trends Shaping the Market:

• Shift towards bio-based and green solvents in pharmaceutical manufacturing

• Increasing adoption in polymer chemistry as a safer alternative to THF

• Stringent environmental regulations phasing out chlorinated and hazardous solvents

• Expansion of production capacities to meet rising demand from Asia-Pacific markets

Get Full Report Here: 2-Methyltetrahydrofuran Market – View in Detailed Research Report

The companies listed above are not only supplying a critical chemical intermediate—they are enabling the transition to safer, more sustainable chemical processes across multiple industries.