Top 10 Companies in the 4-Phenylbutyric Acid Industry (2025): Market Leaders Driving Pharmaceutical Innovation

In Business Insights
October 24, 2025


The Global 4-Phenylbutyric Acid Market was valued at USD 122.8 Million in 2023 and is projected to reach USD 168.5 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 4.7% during the forecast period (2024–2030). This growth is being driven by increasing applications in pharmaceutical intermediates, rising demand for high-purity chemical compounds, and the expanding therapeutic applications across neurology, oncology, and metabolic disorders.

As the pharmaceutical and chemical industries continue to evolve with precision medicine and advanced manufacturing, the spotlight is on the key manufacturers who are driving innovation, quality control, and supply chain reliability. In this blog, we profile the Top 10 Companies in the 4-Phenylbutyric Acid Industry—a mix of established chemical manufacturers, pharmaceutical intermediates producers, and specialty chemical innovators shaping the future of this critical compound.


🔟 1. Zhejiang Shaxing Technology Co., Ltd.

Headquarters: Shaoxing, Zhejiang, China
Key Offering: 98% Purity 4-Phenylbutyric Acid, 99% Purity Pharmaceutical Grade

Zhejiang Shaxing Technology is one of China’s leading producers of 4-Phenylbutyric Acid, specializing in high-purity grades for pharmaceutical applications. Their manufacturing facilities adhere to strict quality control standards, serving both domestic and international markets with consistent product quality and reliable supply chains.

Manufacturing Capabilities:

  • Advanced purification technologies for high-purity grades

  • Strategic partnerships with global pharmaceutical companies

  • Continuous expansion of production capacity to meet growing market demand

Download FREE Sample Report: Global 4-Phenylbutyric Acid Market – View in Detailed Research Report


9️⃣ 2. Seqens

Headquarters: Paris, France
Key Offering: Pharmaceutical Grade 4-PBA, Ultra-Pure Chemical Intermediates

Seqens is a global leader in pharmaceutical solutions and specialty chemicals, offering high-quality 4-Phenylbutyric Acid through their extensive chemical synthesis expertise. The company operates multiple GMP-certified facilities across Europe and North America, ensuring consistent quality for critical pharmaceutical applications.

Manufacturing Capabilities:

  • Integrated manufacturing from chemical synthesis to purification

  • Custom synthesis capabilities for specialized pharmaceutical requirements


8️⃣ 3. AlzChem Group AG

Headquarters: Trostberg, Germany
Key Offering: Fine Chemicals, Pharmaceutical Intermediates, 4-PBA

AlzChem is a globally active specialty chemicals company with strong expertise in fine chemicals and pharmaceutical raw materials. Their production capabilities include both standard and custom synthesis of 4-Phenylbutyric Acid with rigorous quality assurance.

Manufacturing Capabilities:

  • Manufacturing plants in Germany and China

  • Focus on neurodegenerative and metabolic disorder applications


7️⃣ 4. Tokyo Chemical Industry Co., Ltd.

Headquarters: Tokyo, Japan
Key Offering: Research Grade 4-PBA, Laboratory Chemicals

Tokyo Chemical Industry (TCI) is a leading global manufacturer of laboratory chemicals and fine chemicals, including high-purity 4-Phenylbutyric Acid. TCI serves pharmaceutical companies, research institutions, and academic laboratories worldwide with high-purity chemical compounds.

Manufacturing Capabilities:

  • Extensive portfolio of specialty chemicals for research and development

  • Advanced analytical laboratories for quality verification

Download FREE Sample Report: Global 4-Phenylbutyric Acid Market – View in Detailed Research Report


6️⃣ 5. Merck KGaA

Headquarters: Darmstadt, Germany
Key Offering: Life Science Reagents, Pharmaceutical Intermediates

Merck KGaA, through its Life Science business, offers high-purity chemicals including 4-Phenylbutyric Acid for research and pharmaceutical applications.

Manufacturing Capabilities:

  • Manufacturing capabilities for pharmaceutical-grade compounds

  • Global distribution network serving pharmaceutical manufacturers and research institutions


5️⃣ 6. Spectrum Chemical Mfg. Corp.

Headquarters: Gardena, California, USA
Key Offering: GMP-grade Chemicals, Pharmaceutical Raw Materials

Spectrum Chemical is a leading manufacturer and worldwide supplier of fine chemicals and laboratory products, including 4-Phenylbutyric Acid. The company provides comprehensive quality documentation and regulatory support for pharmaceutical customers.

Manufacturing Capabilities: