The Global Mono-Ammonium Glycyrrhizinate Market was valued at USD 140 Million in 2022 and is projected to reach USD 220 Million by 2029, growing at a Compound Annual Growth Rate (CAGR) of 6.8% during the forecast period (2023–2029). This growth is being driven by rising demand for natural sweeteners and anti-inflammatory agents in pharmaceuticals, cosmetics, and the food industry, coupled with increasing consumer preference for clean-label products and health-focused formulations in emerging markets.

As the natural ingredients sector evolves toward sustainable sourcing and multifunctional bioactive compounds, the focus sharpens on leading manufacturers who are advancing extraction technologies, purity standards, and applications in therapeutic and cosmetic products. In this blog, we profile the Top 10 Companies in the Mono-Ammonium Glycyrrhizinate Industry—a blend of pharmaceutical specialists, biotech innovators, and global suppliers shaping the future of glycyrrhizinate derivatives for health and wellness.

---

🔟 1. Tiansheng Pharmaceutical

Headquarters: Xi’an, Shaanxi Province, China
Key Offering: High-purity Mono-Ammonium Glycyrrhizinate for pharmaceuticals and cosmetics

Tiansheng Pharmaceutical stands out as a prominent producer in the Mono-Ammonium Glycyrrhizinate space, specializing in the extraction and refinement of licorice root derivatives. The company supplies high-quality grades used in anti-inflammatory medications, skin care formulations, and oral health products, serving major clients across Asia and Europe. With a strong emphasis on traditional Chinese medicine integration, Tiansheng has expanded its production capacity to meet the surging demand for natural alternatives to synthetic sweeteners and preservatives.

Key Initiatives:

• Investments in advanced chromatography for ultra-high purity levels exceeding 98%

• Partnerships with cosmetic giants for anti-melanin and antioxidant applications

• Commitment to sustainable licorice sourcing from controlled farmlands in Inner Mongolia

Download FREE Sample Report: Mono-Ammonium Glycyrrhizinate Market – View in Detailed Research Report

---

9️⃣ 2. Alps Pharmaceutical

Headquarters: Gifu, Japan
Key Offering: Pharmaceutical-grade Mono-Ammonium Glycyrrhizinate, including Minophagen-branded variants

Alps Pharmaceutical, a key player from Japan, excels in producing Mono-Ammonium Glycyrrhizinate for liver protection and anti-ulcer treatments. Operating with stringent Japanese pharmacopeia standards, the company distributes its products to hospitals and pharmacies worldwide, particularly in Asia-Pacific regions where herbal-derived therapies are popular. Their focus on clinical efficacy has positioned them as a trusted supplier for formulations targeting viral infections and inflammatory conditions.

Key Initiatives:

• Research collaborations with universities on antiviral properties

• Expansion of low-purity grades for cost-effective food industry uses

---

8️⃣ 3. Xinjiang Kunlunshengnong

Headquarters: Urumqi, Xinjiang, China
Key Offering: Bulk Mono-Ammonium Glycyrrhizinate for food and pharmaceutical applications

Xinjiang Kunlunshengnong leverages the region’s abundant licorice resources to produce large volumes of Mono-Ammonium Glycyrrhizinate, catering primarily to the food and beverage sector as a natural sweetener. The company’s vertically integrated operations, from cultivation to processing, ensure consistent supply and quality, making it a vital partner for international exporters seeking reliable raw materials for health supplements and confectionery.

Key Initiatives:

• Organic certification programs for sustainable harvesting

• Development of customized purity levels for export markets

---

7️⃣ 4. Ruihong Bio-technique

Headquarters: Shandong Province, China
Key Offering: High and low-purity Mono-Ammonium Glycyrrhizinate extracts

Ruihong Bio-technique is renowned for its biotechnological approaches to isolating Mono-Ammonium Glycyrrhizinate, offering versatile products for cosmetics and pharmaceuticals. By employing enzymatic hydrolysis methods, the company achieves higher yields and bioactivity, which has boosted its presence in the global anti-aging skincare market. Their products are widely used in creams and serums for their soothing and antioxidant effects.

Key Initiatives:

• Goal to increase production capacity by 20% annually through biotech upgrades

• Strategic alliances with European cosmetic firms for joint R&D

Download FREE Sample Report: Mono-Ammonium Glycyrrhizinate Market – View in Detailed Research Report

---

6️⃣ 5. ELION Group

Headquarters: Beijing, China
Key Offering: Industrial-scale Mono-Ammonium Glycyrrhizinate for multiple sectors

ELION Group, a diversified conglomerate, plays a significant role in the bulk production of Mono-Ammonium Glycyrrhizinate, supplying it for use in tobacco flavoring, food additives, and pharmaceutical excipients. Their extensive distribution network spans Asia, Africa, and the Middle East, where demand for natural flavor enhancers is growing. The group’s emphasis on quality control has earned certifications from international bodies, ensuring compliance with global standards.

Key Initiatives:

• Integration of AI in extraction processes for efficiency gains

• Exploration of new applications in veterinary medicine

---

5️⃣ 6. Hunan Dinuo Pharmaceutical

Headquarters: Changsha, Hunan Province, China
Key Offering: Specialty Mono-Ammonium Glycyrrhizinate for oral care and therapeutics

Hunan Dinuo Pharmaceutical focuses on developing Mono-Ammonium Glycyrrhizinate-based products for throat and dental care, capitalizing on its antibacterial and soothing properties. As a leader in the Chinese pharmaceutical landscape, the company exports to over 30 countries, supporting formulations in cough syrups and mouthwashes. Their commitment to clinical trials underscores a dedication to evidence-based health solutions.

Key Initiatives:

• Current output exceeding 500 tons annually

• Target to double capacity by 2027 through facility expansions

---

4️⃣ 7. Minophagen Pharmaceutical

Headquarters: Tokyo, Japan
Key Offering: High-purity Mono-Ammonium Glycyrrhizinate for liver and anti-inflammatory drugs

Minophagen Pharmaceutical is a pioneer in glycyrrhizinate applications, particularly for treating chronic liver diseases with its flagship product Stronger Neo-Minophagen C. The company’s rigorous R&D has led to innovations in intravenous formulations, making it a go-to supplier for medical institutions in Japan and beyond. Their expertise in pharmacokinetics ensures optimal bioavailability in therapeutic uses.

Key Initiatives:

• Ongoing studies on glycyrrhizinate’s role in metabolic disorders

• Expansion into cosmetic-grade variants for skin health

Download FREE Sample Report: Mono-Ammonium Glycyrrhizinate Market – View in Detailed Research Report

---

3️⃣ 8. Xinjiang TIANSHAN Pharmaceuticals Industry

Headquarters: Urumqi, Xinjiang, China
Key Offering: Natural Mono-Ammonium Glycyrrhizinate for food and pharma

Xinjiang TIANSHAN Pharmaceuticals Industry harnesses local biodiversity to produce Mono-Ammonium Glycyrrhizinate, emphasizing its use in traditional Uyghur medicine and modern nutraceuticals. Serving the domestic market dominantly, the company is venturing into exports, providing low-calorie sweeteners for the growing functional food sector. Their sustainable practices include eco-friendly extraction to preserve Xinjiang’s ecosystems.

Key Initiatives:

• Indigenous research on licorice variants for enhanced bioactivity

• Collaborations with food processors for customized blends

---

2️⃣ 9. Shaanxi Fujie Pharmaceutical

Headquarters: Xi’an, Shaanxi Province, China
Key Offering: Multi-grade Mono-Ammonium Glycyrrhizinate for cosmetics and health products

Shaanxi Fujie Pharmaceutical specializes in the purification of Mono-Ammonium Glycyrrhizinate for high-end cosmetics, where it serves as an anti-irritant and whitening agent. With a portfolio that includes partnerships with global beauty brands, the company has scaled operations to support the booming K-beauty and clean beauty trends. Their focus on stability testing ensures product longevity in formulations.

Key Initiatives:

• Aims to achieve 99% purity standards for premium markets

• Major investments in supply chain traceability

---

1️⃣ 10. MAFCO Worldwide

Headquarters: McCook, Illinois, USA
Key Offering: Global supply of Mono-Ammonium Glycyrrhizinate for food, pharma, and tobacco

MAFCO Worldwide leads in the Western market for Mono-Ammonium Glycyrrhizinate, distributing it for flavor enhancement in tobacco and as a sweetener in beverages. As one of the few non-Asian majors, the company bridges Eastern production with Western demand, offering logistics solutions and regulatory compliance support. Their versatility spans from high-purity pharma grades to industrial applications.

Key Initiatives:

• End-to-end solutions including blending and certification services

• Strategic partnerships with sustainable suppliers in Asia

Get Full Report Here: Mono-Ammonium Glycyrrhizinate Market – View in Detailed Research Report

---

🌍 Outlook: The Future of Mono-Ammonium Glycyrrhizinate Is Natural and Multifunctional

The Mono-Ammonium Glycyrrhizinate market is experiencing a vibrant evolution. While traditional pharmaceutical uses remain core, the sector is channeling significant resources into natural cosmetic integrations, advanced purification techniques, and expanded food applications to align with wellness trends.

📈 Key Trends Shaping the Market:

• Rapid expansion in high-purity segments for anti-aging and skin brightening in cosmetics

• Regulatory advancements supporting natural sweeteners with low-calorie profiles

• Digital tracking of supply chains for authenticity and sustainability verification

• Cross-industry alliances between pharma, food, and biotech for innovative formulations

Get Full Report Here: Mono-Ammonium Glycyrrhizinate Market – View in Detailed Research Report

The companies highlighted here are not only supplying essential glycyrrhizinate compounds—they’re pioneering the natural wellness revolution across global industries.