The Global Dry Granulation Excipients Market was valued at US$ 1,250 million in 2022 and is projected to reach US$ 1,850 million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 5.1% during the forecast period (2023–2030). This growth is being driven by expanding pharmaceutical production, the need for cost-effective granulation processes, and rising demand for high-quality excipients that ensure tablet stability and bioavailability in oral solid dosage forms.

As the pharmaceutical industry advances toward more efficient manufacturing techniques and sustainable practices, attention turns to the essential suppliers of dry granulation excipients who enable faster, solvent-free production methods. These materials, including binders, diluents, and lubricants, play a critical role in creating robust granules without the moisture-related challenges of wet granulation. In this blog, we profile the Top 10 Companies in the Dry Granulation Excipients Industry—a blend of global chemical giants, specialized pharma suppliers, and innovation-driven firms shaping the future of tablet formulation and drug delivery.

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🔟 1. BASF SE

Headquarters: Ludwigshafen, Germany
Key Offering: Kollidon (PVP-based binders), Ludipress (direct compression excipient), Magnesium Stearate (lubricants)

BASF stands as a powerhouse in the excipients space, providing a wide array of materials optimized for dry granulation processes used in tablet manufacturing. Their portfolio supports pharmaceutical companies worldwide by offering excipients that enhance powder flow, compressibility, and disintegration, making them indispensable for producing high-volume generics and complex formulations. With a focus on scalability, BASF’s solutions are integrated into production lines across North America, Europe, and Asia, helping manufacturers reduce processing times and improve yield.

Innovation Initiatives:

• Development of multifunctional excipients like Polyplasdone for superior disintegration

• Collaborations with pharma firms to customize excipient blends for dry granulation

• Commitment to sustainable sourcing and eco-friendly production methods

Download FREE Sample Report: Dry Granulation Excipients Market – View in Detailed Research Report

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9️⃣ 2. Dow Chemical Company

Headquarters: Midland, Michigan, USA
Key Offering: Methocel (HPMC-based binders), Ethocel (ethylcellulose), Specialty lubricants

Dow is renowned for its polymer-based excipients that excel in dry granulation, providing controlled release and moisture protection for sensitive active pharmaceutical ingredients (APIs). Operating in over 30 countries, Dow supplies excipients that facilitate roller compaction and slugging techniques, ensuring consistent granule quality for oral tablets. Their emphasis on R&D has led to excipients compatible with high-speed tableting, addressing the needs of contract manufacturers and big pharma alike.

Innovation Initiatives:

• Advancements in polymer excipients for improved API stability during dry processing

• Partnerships with equipment makers to optimize granulation machinery

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8️⃣ 3. Ashland Global Holdings Inc.

Headquarters: Wilmington, Delaware, USA
Key Offering: Pharmaburst (co-processed excipients), Klucel (HPC binders), Stearic acid derivatives

Ashland delivers innovative excipient solutions tailored for dry granulation, focusing on enhancing tablet hardness and dissolution rates. Their products are widely used in the production of immediate-release and extended-release formulations, serving the global pharma market through a robust supply chain. Ashland’s expertise in co-processing allows for streamlined dry granulation workflows, reducing the number of unit operations and minimizing waste in manufacturing.

Innovation Initiatives:

• Investment in co-processed excipients for one-step dry granulation

• Sustainability programs reducing carbon footprint in excipient production

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7️⃣ 4. Roquette Frères

Headquarters: Lestrem, France
Key Offering: Pearlitol (mannitol diluents), Lycatab (PVP binders), Glucidex (maltodextrins for glidants)

Roquette, a leader in plant-based excipients, specializes in natural and semi-synthetic materials ideal for dry granulation in nutraceuticals and pharmaceuticals. With production facilities in Europe and Asia, they supply excipients that improve flowability and compressibility, supporting the shift toward greener manufacturing. Their solutions are particularly valued for hypoallergenic properties and compatibility with heat-sensitive APIs, making them a go-to for ethical drug formulators.

Innovation Initiatives:

• Expansion of bio-based excipient lines for sustainable dry granulation

• Target to increase renewable content in excipients to 50% by 2030

Download FREE Sample Report: Dry Granulation Excipients Market – View in Detailed Research Report

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6️⃣ 5. Gattefossé

Headquarters: Lyon, France
Key Offering: Compritol (glyceryl behenate lubricants), Gelucire (multi-functional excipients), Lipicol (for glidants)

Gattefossé excels in lipid-based excipients that enhance lubrication and flow in dry granulation processes, crucial for avoiding sticking and capping in tablets. Their global reach extends to over 100 countries, where they support innovative drug delivery systems like orally disintegrating tablets. By focusing on multifunctional excipients, Gattefossé helps manufacturers achieve higher efficiency and compliance with stringent regulatory standards.

Innovation Initiatives:

• R&D into lipid excipients for better granule uniformity

• Certifications for GMP and sustainability in excipient manufacturing

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5️⃣ 6. DFE Pharma

Headquarters: Goch, Germany
Key Offering: Ludiflash (co-processed disintegrants), Microcrystalline cellulose (MCC) diluents, Emcompress

DFE Pharma is a dedicated excipient specialist, offering co-processed materials that simplify dry granulation for direct compression and roller compaction. Their products are engineered for superior binding and rapid disintegration, serving major pharma hubs in Europe and the US. DFE’s commitment to quality has earned them partnerships with leading CDMOs, enabling faster time-to-market for new drug products.

Innovation Initiatives:

• Current output of co-processed excipients exceeding 50,000 tons annually

• Goal to double production capacity by 2027 through facility expansions

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4️⃣ 7. Colorcon Inc.

Headquarters: Harleysville, Pennsylvania, USA
Key Offering: Opadry (functional coatings with excipients), Sureteric (for glidants), Advantab

Colorcon provides integrated excipient and coating solutions that complement dry granulation, ensuring tablets meet aesthetic and performance criteria. With a presence in emerging markets like India and China, they cater to the growing demand for affordable, high-quality formulations. Their expertise in particle engineering helps optimize granule attributes for consistent tableting results.

Innovation Initiatives:

• Development of low-moisture excipients for sensitive APIs

• Collaborative R&D with pharma innovators on customized dry granulation systems

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3️⃣ 8. JRS Pharma GmbH & Co. KG

Headquarters: Rosenberg, Germany
Key Offering: Vivapur (MCC diluents), Prosolv (co-processed excipients), Emdex (for direct compression)

JRS Pharma focuses on cellulose-based excipients that provide excellent compressibility in dry granulation, ideal for high-dose APIs. As a family-owned company, they emphasize reliability and innovation, supplying to over 70 countries with tailored solutions for nutraceutical and biopharma applications. Their products help reduce formulation challenges, promoting efficient scale-up from lab to commercial production.

Innovation Initiatives:

• Indigenous research into sustainable cellulose sourcing

• Public-private partnerships to advance excipient standards

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2️⃣ 9. FMC Corporation

Headquarters: Philadelphia, Pennsylvania, USA
Key Offering: Avicel (MCC binders), Ac-Di-Sol (superdisintegrants), Specialty glidants

FMC is a key player in providing disintegrants and binders for dry granulation, enhancing tablet performance in terms of breakup and absorption. Their global operations support the pharmaceutical industry’s push for faster dissolution profiles, particularly in over-the-counter products. FMC’s investments in bioprocessing ensure their excipients align with modern manufacturing demands.

Innovation Initiatives:

• Aiming to produce 100,000 tons/year of advanced excipients

• Expansion of supply chains for Asian and Latin American markets

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1️⃣ 10. GEA Group Aktiengesellschaft

Headquarters: Düsseldorf, Germany
Key Offering: Excipients for integrated granulation systems, Binders and lubricants, Process aids

GEA combines excipient supply with equipment expertise, offering holistic solutions for dry granulation lines. They support thousands of installations worldwide, providing excipients that optimize roller compaction and fluid bed processes. As leaders in process engineering, GEA enables pharma companies to achieve higher throughput and quality control in excipient-dependent manufacturing.

Innovation Initiatives:

• End-to-end solutions integrating excipients with granulation technology

• Strategic alliances with excipient producers for seamless integration

Read Full Report: Dry Granulation Excipients Market – View in Detailed Research Report

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🌍 Outlook: The Future of Dry Granulation Excipients Is Innovative and Sustainable

The dry granulation excipients market is experiencing significant evolution. While traditional materials remain foundational, the sector is channeling substantial resources into multifunctional, bio-based alternatives, advanced co-processing, and integrated process technologies to meet the demands of modern pharmaceuticals.

📈 Key Trends Shaping the Market:

• Acceleration in bio-based and sustainable excipient development across Europe, North America, and Asia

• Regulatory requirements for enhanced excipient characterization and impurity control by 2030

• Adoption of Industry 4.0 technologies for smart granulation and excipient optimization

• Strategic mergers and collaborations between excipient suppliers and pharma equipment providers

Read Full Report: Dry Granulation Excipients Market – View in Detailed Research Report

The companies highlighted here are not just supplying materials—they’re at the forefront of transforming pharmaceutical manufacturing into a more efficient, eco-conscious powerhouse.