The Global and United States 2-Methyl-4-Isothiazolin-3-One (CAS 2682-20-4) Market was valued at USD 132.5 Million in 2023 and is projected to reach USD 215.8 Million by 2029, growing at a Compound Annual Growth Rate (CAGR) of 8.7% during the forecast period (2023–2029). This growth is being driven by rising demand in personal care products, cosmetics, and industrial applications like coatings and pulp processing, coupled with increasing awareness of microbial control solutions, though tempered by regulatory scrutiny on allergenicity in consumer goods.

As the chemical industry evolves toward safer, more effective preservatives and fungicides, the spotlight is on the key manufacturers who are driving innovation, compliance, and antimicrobial advancements. In this blog, we profile the Top 10 Companies in the 2-Methyl-4-Isothiazolin-3-One (CAS 2682-20-4) Market—a blend of global specialists, regional producers, and application-focused suppliers shaping the future of chemical applications worldwide and in the United States.

---

🔟 1. Santa Cruz Biotechnology

Headquarters: Dallas, Texas, USA
Key Offering: High-purity 2-Methyl-4-Isothiazolin-3-One for research and industrial use

Santa Cruz Biotechnology stands out as a prominent supplier in the US market, providing ultra-pure grades of 2-Methyl-4-Isothiazolin-3-One (MIT) tailored for laboratory and small-scale industrial applications. Their products are widely used in biochemical research and formulation development, ensuring high efficacy in microbial inhibition across various testing environments.

Market Focus Areas:

• Specialized formulations for personal care and cosmetic testing

• Compliance with stringent US regulatory standards like FDA guidelines

• Global distribution reaching over 50 countries

Download FREE Sample Report: Global and United States 2-Methyl-4-Isothiazolin-3-One (CAS 2682-20-4) Market – View in Detailed Research Report

---

9️⃣ 2. Promchem

Headquarters: Shanghai, China
Key Offering: Industrial-grade MIT as fungicide and preservative

Promchem is a key player in the Asia-Pacific region, supplying cost-effective 2-Methyl-4-Isothiazolin-3-One for large-scale applications in coatings and pulp industries. Their production facilities emphasize scalability, allowing them to meet the growing demands from emerging markets where microbial contamination poses significant challenges to manufacturing processes.

Market Focus Areas:

• Export-oriented supply to North America and Europe

• Custom blending services for coating and adhesive sectors

---

8️⃣ 3. Spectrum Chemical

Headquarters: New Brunswick, New Jersey, USA
Key Offering: USP-grade MIT for pharmaceutical and cosmetic preservatives

Spectrum Chemical excels in the United States market by offering certified, high-quality 2-Methyl-4-Isothiazolin-3-One that meets pharmacopeia standards. Their portfolio supports the formulation of personal care products and cosmetics, where effective preservation is critical to extending shelf life without compromising safety.

Market Focus Areas:

• Targeted applications in personal care and cosmetic industries

• Extensive inventory for quick US domestic fulfillment

---

7️⃣ 4. Leap Labchem

Headquarters: Mumbai, India
Key Offering: MIT solutions for pulp and paper preservation

Leap Labchem contributes significantly to the Asia-Pacific and global markets with reliable 2-Methyl-4-Isothiazolin-3-One products optimized for the pulp industry. Their expertise lies in preventing biodeterioration in paper processing, where humidity and organic materials foster microbial growth.

Market Focus Areas:

• Innovative applications in pulp and water treatment

• Growing presence in the US through export partnerships

• Sustainable production practices reducing environmental impact

Download FREE Sample Report: Global and United States 2-Methyl-4-Isothiazolin-3-One (CAS 2682-20-4) Market – View in Detailed Research Report

---

6️⃣ 5. ShanDong Fine Chemical

Headquarters: Jinan, Shandong, China
Key Offering: Bulk MIT for fungicide applications in coatings

ShanDong Fine Chemical is a major force in China’s chemical sector, producing high-volume 2-Methyl-4-Isothiazolin-3-One for use as a fungicide in protective coatings. Their operations support the construction and marine industries globally, where durable antimicrobial protection is essential against mold and mildew.

Market Focus Areas:

• Large-scale production for industrial coatings

• Adaptation to US import regulations for seamless distribution

---

5️⃣ 6. Hangzhou DayangChem

Headquarters: Hangzhou, Zhejiang, China
Key Offering: Versatile MIT grades for cosmetics and personal care

Hangzhou DayangChem specializes in fine chemicals, delivering 2-Methyl-4-Isothiazolin-3-One formulations that enhance product safety in cosmetics. As consumer demand for long-lasting beauty products rises, their solutions provide effective microbial control while addressing formulation challenges.

Market Focus Areas:

• Development of hypoallergenic preservative systems

• Strong export network to the United States market

---

4️⃣ 7. Hangzhou J&H Chemical

Headquarters: Hangzhou, China
Key Offering: MIT for diverse applications including pulp and others

Hangzhou J&H Chemical offers a broad range of 2-Methyl-4-Isothiazolin-3-One products, serving niche markets like pulp preservation and specialty coatings. Their integrated manufacturing approach ensures consistent quality, making them a preferred supplier for companies seeking reliable antimicrobial agents.

Market Focus Areas:

• Customization for pulp and specialty chemical uses

• Compliance with international safety and efficacy standards

---

3️⃣ 8. Shanghai Orgpharma Chemical

Headquarters: Shanghai, China
Key Offering: Pharmaceutical-grade MIT as preservative

Shanghai Orgpharma Chemical focuses on organic synthesis, providing high-purity 2-Methyl-4-Isothiazolin-3-One for preservative roles in personal care and pharmaceutical intermediates. Their expertise in scalable production supports the expanding US market for safe, effective biocides.

Market Focus Areas:

• Applications in personal care and cosmetic preservation

• R&D collaborations for US regulatory approvals

---

2️⃣ 9. Thor GmbH

Headquarters: Speyer, Germany
Key Offering: Advanced MIT-based biocides for industrial and consumer uses

Thor GmbH, a leader in biocide solutions, produces 2-Methyl-4-Isothiazolin-3-One integrated into multifunctional preservative systems for coatings, personal care, and pulp applications. Operating across Europe and exporting to the US, they emphasize formulation expertise to optimize efficacy at lower dosages.

Market Focus Areas:

• Integrated solutions for coatings and personal care

• Strong compliance with US EPA and EU REACH regulations

---

1️⃣ 10. Lonza Group

Headquarters: Basel, Switzerland
Key Offering: Specialty MIT formulations for cosmetics and industrial preservation

Lonza Group tops the list as a global innovator in microbial control, offering 2-Methyl-4-Isothiazolin-3-One in advanced blends for cosmetics, personal care, and other sectors. Their US operations, including facilities in Georgia, enable direct service to North American clients, focusing on high-performance preservatives.

Market Focus Areas:

• Premium products for cosmetic and personal care industries

• Global supply chain with dedicated US manufacturing

• Focus on regulatory-compliant, low-allergen innovations

Read Full Report: Global and United States 2-Methyl-4-Isothiazolin-3-One (CAS 2682-20-4) Market – View in Detailed Research Report

---

🌍 Outlook: The Future of 2-Methyl-4-Isothiazolin-3-One Market Is Innovative and Compliant

The 2-Methyl-4-Isothiazolin-3-One market is experiencing steady evolution, with traditional applications in preservatives and fungicides remaining core, while investments pour into safer formulations and expanded uses in emerging sectors.

📈 Key Trends Shaping the Market:

• Shift toward combination preservatives reducing MIT usage in cosmetics

• Regulatory mandates in the US and EU for allergen disclosure by 2025

• Digital tracking of supply chains for compliance and traceability

• Partnerships between chemical firms and end-users for customized solutions

Read Full Report: Global and United States 2-Methyl-4-Isothiazolin-3-One (CAS 2682-20-4) Market – View in Detailed Research Report

The companies listed above are not only supplying essential antimicrobial solutions—they’re leading the responsible innovation in global chemical applications.