The Global 2-Methylbutanedioic Acid Market was valued at USD 42.8 Million in 2022 and is projected to reach USD 63.1 Million by 2029, growing at a Compound Annual Growth Rate (CAGR) of 5.7% during the forecast period (2024-2029). This growth is driven by rising demand for pharmaceutical intermediates, food-grade additives, and high-purity chemical applications across global markets.
As industries increasingly demand versatile organic acids for critical manufacturing processes, 2-Methylbutanedioic Acid (CAS 498-21-5) has become a key intermediate in pharmaceutical synthesis and specialty chemical production. This analysis examines the Top 10 Companies in the 2-Methylbutanedioic Acid Market that are leading production capabilities, technological innovation, and global supply chain development.
🔟 1. Beijing Risun Technology Co., Ltd.
Headquarters: Beijing, China
Key Offering: Pharmaceutical and Food Grade (98-99% purity)
Beijing Risun Technology dominates the Chinese market for 2-Methylbutanedioic Acid production with state-of-the-art manufacturing facilities. The company supplies API manufacturers and food additive producers across Asia and Europe.
Market Position:
- 30% market share in Asia Pacific region
- 5,000 MT annual production capacity
- ISO 9001 certified facilities
Download FREE Sample Report: 2-Methylbutanedioic Acid Market – View in Detailed Research Report
9️⃣ 2. Xiang Yang Nuo Er Chemical Co., Ltd.
Headquarters: Hubei, China
Key Offering: Technical and Industrial Grade
Xiang Yang Nuo Er Chemical operates one of China’s largest continuous production lines for 2-Methylbutanedioic Acid, serving bulk chemical buyers and industrial applications.
Market Position:
- 40% revenue growth year-over-year
- Vertically integrated production from raw materials
- Major exporter to Southeast Asian markets
8️⃣ 3. Hefei TNJ Chemical Industry Co., Ltd.
Headquarters: Anhui, China
Key Offering: Pharmaceutical Intermediates
TNJ Chemical specializes in high-purity 2-Methylbutanedioic Acid for global pharmaceutical supply chains, with strict quality control systems meeting international pharmacopeia standards.
Market Position:
- USP/EP grade production capabilities
- Strategic partnerships with major drug manufacturers
- GMP-compliant manufacturing processes
7️⃣ 4. Tokyo Chemical Industry Co., Ltd. (TCI)
Headquarters: Tokyo, Japan
Key Offering: High-Purity Laboratory Reagents
TCI supplies research-grade 2-Methylbutanedioic Acid to academic institutions and pharmaceutical R&D centers worldwide, with unparalleled purity standards.
Market Position:
- 99.9%+ purity formulations
- Global distribution to over 50 countries
- Technical support for analytical applications
Download FREE Sample Report: 2-Methylbutanedioic Acid Market – View in Detailed Research Report
6️⃣ 5. Hangzhou Dayangchem Co., Ltd.
Headquarters: Zhejiang, China
Key Offering: Custom Synthesis Services
Dayangchem provides both standard and tailored 2-Methylbutanedioic Acid solutions for specialty chemical manufacturers, with flexible production scales from kg to ton quantities.
Market Position:
- 500MT+ annual capacity
- Custom purity and packaging options
- Strong presence in emerging markets
5️⃣ 6. Sigma-Aldrich (Merck KGaA)
Headquarters: Darmstadt, Germany
Key Offering: Analytical and HPLC Grade
As part of Merck’s life science division, Sigma-Aldrich supplies ultra-pure 2-Methylbutanedioic Acid for quality control and research applications in regulated industries.
Market Position:
- Certified reference materials
- Batch-specific documentation
- Global regulatory compliance
4️⃣ 7. Alfa Aesar (Thermo Fisher Scientific)
Headquarters: Massachusetts, USA
Key Offering: Research Chemicals
Alfa Aesar provides high-purity 2-Methylbutanedioic Acid to research institutions and specialty chemical manufacturers through Thermo Fisher’s extensive global distribution network.
Market Position:
- Metrology-grade standards
- Custom packaging solutions
- Technical documentation support
3️⃣ 8. Biosynth Carbosynth
Headquarters: Staad, Switzerland
Key Offering: Pharmaceutical Building Blocks
This Swiss specialty chemical company provides certified 2-Methylbutanedioic Acid for drug development and manufacturing processes meeting rigorous European quality standards.
Market Position:
- ICH Q7 compliant manufacturing
- Regulatory support services
- Stable isotope-labeled compounds
2️⃣ 9. Toronto Research Chemicals
Headquarters: Ontario, Canada
Key Offering: Certified Reference Materials
TRC specializes in authenticated 2-Methylbutanedioic Acid standards for analytical testing and method validation in pharmaceutical quality control laboratories.
Market Position:
- GMP-manufactured reference standards
- Method development support
- FDA/EMA compliant documentation
1️⃣ 10. Capot Chemical Co., Ltd.
Headquarters: Zhejiang, China
Key Offering: Industrial Chemicals
Capot Chemical has emerged as a reliable bulk supplier of 2-Methylbutanedioic Acid, with expanding distribution networks across Asia and Middle Eastern markets.
Market Position:
- Competitive pricing for bulk orders
- Container quantity capabilities
- Rapid response to market demands
Get Full Report Here: 2-Methylbutanedioic Acid Market – View in Detailed Research Report
🌍 Market Outlook: Expanding Applications Drive Growth
The 2-Methylbutanedioic Acid market is poised for steady expansion as pharmaceutical and specialty chemical applications continue to diversify. While drug intermediates currently account for over 60% of demand, emerging uses in food preservation and polymer production show significant potential.
📈 Key Market Trends:
- Growing demand for high-purity pharmaceutical intermediates
- Increasing R&D investment in chiral compound synthesis
- Expansion of Chinese manufacturers in international markets
- Stringent quality requirements for food-grade applications
Get Full Report Here: 2-Methylbutanedioic Acid Market – View in Detailed Research Report
The companies profiled represent the leading innovators and suppliers shaping the global 2-Methylbutanedioic Acid market’s trajectory through 2025 and beyond.
- Top 10 Companies in the Octafluorocyclobutane Industry (2025): Market Leaders Driving Specialty Gas Innovation - September 10, 2025
- Alpha-GPC Market, Global Outlook and Forecast 2023-2032 - September 10, 2025
- Top 10 Companies in the Minimally Invasive Medical Robotics Industry (2025): Pioneers Advancing Precision Surgery - September 10, 2025