Top 10 Companies in the 2-Methylbutanedioic Acid Industry (2025): Market Leaders Powering Specialty Chemical Innovation

In Business Insights
September 09, 2025

The Global 2-Methylbutanedioic Acid Market was valued at USD 42.8 Million in 2022 and is projected to reach USD 63.1 Million by 2029, growing at a Compound Annual Growth Rate (CAGR) of 5.7% during the forecast period (2024-2029). This growth is driven by rising demand for pharmaceutical intermediates, food-grade additives, and high-purity chemical applications across global markets.

As industries increasingly demand versatile organic acids for critical manufacturing processes, 2-Methylbutanedioic Acid (CAS 498-21-5) has become a key intermediate in pharmaceutical synthesis and specialty chemical production. This analysis examines the Top 10 Companies in the 2-Methylbutanedioic Acid Market that are leading production capabilities, technological innovation, and global supply chain development.


🔟 1. Beijing Risun Technology Co., Ltd.

Headquarters: Beijing, China
Key Offering: Pharmaceutical and Food Grade (98-99% purity)

Beijing Risun Technology dominates the Chinese market for 2-Methylbutanedioic Acid production with state-of-the-art manufacturing facilities. The company supplies API manufacturers and food additive producers across Asia and Europe.

Market Position:

  • 30% market share in Asia Pacific region
  • 5,000 MT annual production capacity
  • ISO 9001 certified facilities

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9️⃣ 2. Xiang Yang Nuo Er Chemical Co., Ltd.

Headquarters: Hubei, China
Key Offering: Technical and Industrial Grade

Xiang Yang Nuo Er Chemical operates one of China’s largest continuous production lines for 2-Methylbutanedioic Acid, serving bulk chemical buyers and industrial applications.

Market Position:

  • 40% revenue growth year-over-year
  • Vertically integrated production from raw materials
  • Major exporter to Southeast Asian markets

8️⃣ 3. Hefei TNJ Chemical Industry Co., Ltd.

Headquarters: Anhui, China
Key Offering: Pharmaceutical Intermediates

TNJ Chemical specializes in high-purity 2-Methylbutanedioic Acid for global pharmaceutical supply chains, with strict quality control systems meeting international pharmacopeia standards.

Market Position:

  • USP/EP grade production capabilities
  • Strategic partnerships with major drug manufacturers
  • GMP-compliant manufacturing processes

7️⃣ 4. Tokyo Chemical Industry Co., Ltd. (TCI)

Headquarters: Tokyo, Japan
Key Offering: High-Purity Laboratory Reagents

TCI supplies research-grade 2-Methylbutanedioic Acid to academic institutions and pharmaceutical R&D centers worldwide, with unparalleled purity standards.

Market Position:

  • 99.9%+ purity formulations
  • Global distribution to over 50 countries
  • Technical support for analytical applications

Download FREE Sample Report: 2-Methylbutanedioic Acid Market – View in Detailed Research Report


6️⃣ 5. Hangzhou Dayangchem Co., Ltd.

Headquarters: Zhejiang, China
Key Offering: Custom Synthesis Services

Dayangchem provides both standard and tailored 2-Methylbutanedioic Acid solutions for specialty chemical manufacturers, with flexible production scales from kg to ton quantities.

Market Position:

  • 500MT+ annual capacity
  • Custom purity and packaging options
  • Strong presence in emerging markets

5️⃣ 6. Sigma-Aldrich (Merck KGaA)

Headquarters: Darmstadt, Germany
Key Offering: Analytical and HPLC Grade

As part of Merck’s life science division, Sigma-Aldrich supplies ultra-pure 2-Methylbutanedioic Acid for quality control and research applications in regulated industries.

Market Position:

  • Certified reference materials
  • Batch-specific documentation
  • Global regulatory compliance

4️⃣ 7. Alfa Aesar (Thermo Fisher Scientific)

Headquarters: Massachusetts, USA
Key Offering: Research Chemicals

Alfa Aesar provides high-purity 2-Methylbutanedioic Acid to research institutions and specialty chemical manufacturers through Thermo Fisher’s extensive global distribution network.

Market Position:

  • Metrology-grade standards
  • Custom packaging solutions
  • Technical documentation support

3️⃣ 8. Biosynth Carbosynth

Headquarters: Staad, Switzerland
Key Offering: Pharmaceutical Building Blocks

This Swiss specialty chemical company provides certified 2-Methylbutanedioic Acid for drug development and manufacturing processes meeting rigorous European quality standards.

Market Position:

  • ICH Q7 compliant manufacturing
  • Regulatory support services
  • Stable isotope-labeled compounds

2️⃣ 9. Toronto Research Chemicals

Headquarters: Ontario, Canada
Key Offering: Certified Reference Materials

TRC specializes in authenticated 2-Methylbutanedioic Acid standards for analytical testing and method validation in pharmaceutical quality control laboratories.

Market Position:

  • GMP-manufactured reference standards
  • Method development support
  • FDA/EMA compliant documentation

1️⃣ 10. Capot Chemical Co., Ltd.

Headquarters: Zhejiang, China
Key Offering: Industrial Chemicals

Capot Chemical has emerged as a reliable bulk supplier of 2-Methylbutanedioic Acid, with expanding distribution networks across Asia and Middle Eastern markets.

Market Position:

  • Competitive pricing for bulk orders
  • Container quantity capabilities
  • Rapid response to market demands

Get Full Report Here: 2-Methylbutanedioic Acid Market – View in Detailed Research Report


🌍 Market Outlook: Expanding Applications Drive Growth

The 2-Methylbutanedioic Acid market is poised for steady expansion as pharmaceutical and specialty chemical applications continue to diversify. While drug intermediates currently account for over 60% of demand, emerging uses in food preservation and polymer production show significant potential.

📈 Key Market Trends:

  • Growing demand for high-purity pharmaceutical intermediates
  • Increasing R&D investment in chiral compound synthesis
  • Expansion of Chinese manufacturers in international markets
  • Stringent quality requirements for food-grade applications

Get Full Report Here: 2-Methylbutanedioic Acid Market – View in Detailed Research Report

The companies profiled represent the leading innovators and suppliers shaping the global 2-Methylbutanedioic Acid market’s trajectory through 2025 and beyond.