The Global Thermostable Phytases Market was valued at USD 350 Million in 2023 and is projected to reach USD 520 Million by 2029, growing at a Compound Annual Growth Rate (CAGR) of 6.8% during the forecast period (2024-2029). This growth is driven by increasing demand for efficient animal feed solutions, rising environmental concerns about phosphate pollution, and expanding applications in food processing industries.

As industries prioritize sustainable agricultural practices and nutritional efficiency, thermostable phytases have become critical tools for phosphate release optimization. In this analysis, we examine the Top 10 Companies in the Thermostable Phytases Industry—biotechnology leaders advancing enzyme innovation for global food systems.

---

🔟 1. BASF SE

Headquarters: Ludwigshafen, Germany
Key Offering: Natuphos® E (thermostable phytase)

BASF leads the phytase market with its high-performance Natuphos E enzyme, specifically engineered for stability in high-temperature feed processing environments. Their solution demonstrates 95% activity retention at 80°C for 3 minutes.

Technical Advantages:

• Wide pH tolerance (2.5-6.5)
• Proven 30% phosphate release increase
• GMP+ certified production facilities

Download FREE Sample Report: Thermostable Phytases Market – View in Detailed Research Report

---

9️⃣ 2. DuPont Nutrition & Biosciences

Headquarters: Wilmington, Delaware, USA
Key Offering: Phytezyme® XP (6-phytase)

DuPont’s phytase enzymes set industry benchmarks for thermal resilience, maintaining >90% activity after standard pelleting conditions. Their microbial fermentation technology enables efficient large-scale production.

Technical Advantages:

• Consistent performance across feed matrices
• FDA-approved for food applications
• Enhanced phosphorus digestibility studies

---

8️⃣ 3. DSM Nutritional Products

Headquarters: Kaiseraugst, Switzerland
Key Offering: Ronozyme® HiPhos

DSM’s fungal phytase demonstrates exceptional stability, with proprietary formulation protecting enzyme activity during storage and feed processing. The company reports 15-30% improvements in phosphorus utilization across species.

Technical Advantages:

• High specific activity (800 FTU/mg)
• Validated reduction in phosphorus excretion
• Sustainability-certified production

---

7️⃣ 4. AB Enzymes

Headquarters: Darmstadt, Germany
Key Offering: Finase® EC

AB Enzymes specializes in E.coli-derived phytases with optimized thermostability profiles. Their enzymes maintain 85% activity after exposure to 85°C for 30 seconds, making them ideal for commercial feed production.

Technical Advantages:

• Broad substrate specificity
• Compatible with all major feed additives
• Validated palatability improvements

Download FREE Sample Report: Thermostable Phytases Market – View in Detailed Research Report

---

6️⃣ 5. Beijing Smistyle Sci. & Tech Development Co.

Headquarters: Beijing, China
Key Offering: SMZY® Thermophilic Phytase

This Chinese innovator has developed phytases with exceptional thermal resistance (>80% stability at 85°C for 10 minutes), combined with high specific activity (5,000 U/mg). Their production process achieves industry-leading yields.

Technical Advantages:

• Cost-effective manufacturing
• Custom formulations for Asian feed markets
• Proprietary strain protection technology

---

5️⃣ 6. VTR Biotech

Headquarters: Istanbul, Turkey
Key Offering: Phyzyme Pro

VTR’s double-coated enzyme technology provides enhanced protection against processing conditions. Independent testing shows 25% better residual activity compared to standard phytases after pelleting.

Technical Advantages:

• Stable across wide pH range
• Reduced enzyme dosage requirements
• Optimized for emerging market conditions

---

4️⃣ 7. Jinan Tiantianxiang (TTX®)

Headquarters: Jinan, China
Key Offering: TTX®-PHY

TTX’s ultra-thermostable phytase demonstrates 92% residual activity after exposure to 85°C for 90 seconds. The company focuses on cost-efficient production for high-volume feed applications.

Technical Advantages:

• Novel Bacillus-derived enzyme
• Enhanced mineral release properties
• Competitive pricing structure

---

3️⃣ 8. Huvepharma

Headquarters: Sofia, Bulgaria
Key Offering: OptiPhos® PLUS

Huvepharma’s fungal phytase delivers consistent performance across diverse feed formulations, with specialized variants for poultry, swine, and aquaculture applications.

Technical Advantages:

• High concentration formulations
• Complete traceability from fermentation
• Validated 1.5:1 Ca:P release ratio

---

2️⃣ 9. Novozymes A/S

Headquarters: Bagsværd, Denmark
Key Offering: Phyzyme® XP

Novozymes combines Scandinavian biotechnology with global application expertise. Their phytase maintains full functionality after 5 minutes at 75°C, with excellent gastric survivability in animals.

Technical Advantages:

• High-activity liquid formulations
• Sustainable production processes
• Comprehensive technical support

---

1️⃣ 10. Vland Biotech Group

Headquarters: Qingdao, China
Key Offering: Vlandzyme® TP

Vland’s patented post-fermentation processing enhances native enzyme stability, resulting in only 10% activity loss at 85°C/30s. The company specializes in APAC market solutions.

Technical Advantages:

• Stable multi-enzyme formulations
• Custom particle size options
• Cost-competitive Asian production

Get Full Report Here: Thermostable Phytases Market – View in Detailed Research Report

---

🔬 Industry Outlook: The Next Generation of Phytase Technology

The thermostable phytase market continues to evolve with advancements in enzyme engineering and production technologies. Current developments focus on extreme thermal resistance, enhanced gastric survivability, and multi-functional enzyme systems.

📈 Emerging Market Trends:

• Development of >90°C stable phytases for expanded processing flexibility
• Integration with other feed enzymes for synergistic effects
• Expansion into aquaculture and pet food applications
• Growing emphasis on sustainable production methods

Get Full Report Here: Thermostable Phytases Market – View in Detailed Research Report

The companies profiled represent the forefront of enzyme innovation—delivering solutions that enhance nutritional efficiency while supporting sustainable agriculture worldwide.