Top 10 Companies in the Liquid Nicotine Industry (2025): Market Leaders Powering Global Vaping Trends

In Business Insights
August 13, 2025

The Global Liquid Nicotine Market was valued at USD 9.2 Billion in 2023 and is projected to reach USD 15.8 Billion by 2030, growing at a Compound Annual Growth Rate (CAGR) of 8.1% during the forecast period (2024-2030). This growth is fueled by increasing demand for e-cigarettes, innovative vaping technologies, and the shift from combustible tobacco products amid rising health consciousness.

As the vaping industry evolves with stricter regulations and technological advancements, key manufacturers are innovating with purity standards, flavor formulations, and nicotine concentration variants. In this analysis, we examine the Top 10 Companies in the Liquid Nicotine Industry—established chemical producers and emerging specialists driving the nicotine formulation landscape.


🔟 1. Feellife Health Inc.

Headquarters: Shenzhen, China
Key Offering: Pharmaceutical-grade nicotine (99.9% purity), custom formulations

Feellife Health leads the market with GMP-certified nicotine production facilities serving global vape brands. Their USP is ultra-high-purity nicotine solutions compliant with FDA, PMTA, and EU TPD regulations.

Innovation Highlights:

  • Patented nicotine salt formulations

  • Invested $50M in new extraction facility (2023)

  • Supplies 18 of top 20 global vape brands

Download FREE Sample Report: Liquid Nicotine Market – View in Detailed Research Report


9️⃣ 2. Hangsen International Group

Headquarters: Hong Kong
Key Offering: Nicotine bases (PG/VG), flavor concentrates

Hangsen controls 22% of global vape liquid OEM production, with vertically integrated operations from tobacco sourcing to finished e-liquids. Their R&D focuses on tobacco-free nicotine alternatives.

Innovation Highlights:

  • 300+ proprietary flavor formulations

  • 5 nicotine extraction patents filed in 2023


8️⃣ 3. China Boton Group

Headquarters: Shenzhen, China
Key Offering: Synthetic nicotine, nicotine bitartrate

China Boton pioneered synthetic nicotine production independent of tobacco, circumventing regulatory hurdles. Their biotech division develops patented fermentation-based nicotine production.

Innovation Highlights:

  • 40,000-ton annual synthetic nicotine capacity

  • USP-grade nicotine for pharma applications


7️⃣ 4. U-GREEN Biotechnology

Headquarters: Shanghai, China
Key Offering: Organic nicotine, nicotine polacrilex

Specializing in “green nicotine,” U-GREEN uses patented CO₂ supercritical extraction for solvent-free production. Their nicotine is certified Kosher, Halal, and vegan-friendly.

Innovation Highlights:

  • Zero-tobacco nicotine from eggplant extract

  • FDA-registered facility (2022)

Download FREE Sample Report: Liquid Nicotine Market – View in Detailed Research Report


6️⃣ 5. Huizhou Hangboo Biotech

Headquarters: Guangdong, China
Key Offering: Nicotine salts, nicotine freebase

Hangboo supplies 70% of China’s domestic vape market with cost-effective nicotine solutions. Their proprietary salt formulation technology optimizes throat hit and vapor production.

Innovation Highlights:

  • High-stability nicotine salts (24-month shelf life)

  • Dual-certified (GMP/ISO) production lines

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