Top 10 Companies in the Global CBD Vape Oil Market (2025): Industry Leaders Driving Cannabidiol Innovation

In Business Insights
August 06, 2025

The Global CBD Vape Oil Market was valued at USD 1.2 Billion in 2023 and is projected to reach USD 3.5 Billion by 2030, growing at a Compound Annual Growth Rate (CAGR) of 16.8% during the forecast period (2024–2030). This expansion is fueled by increasing legalization of cannabis products, growing consumer preference for alternative wellness solutions, and technological advancements in vaporizer devices.

As the CBD industry matures, the market is witnessing intensified competition among brands offering premium vape formulations. In this analysis, we examine the Top 10 Companies in the CBD Vape Oil Market—pioneers in extraction technologies, product safety standards, and cannabinoid innovation.


🔟 1. Kazmira

Headquarters: Denver, Colorado, USA
Key Offering: THC-Free CBD Vape Oils, Full-Spectrum Formulations

Kazmira is a vertically integrated CBD company specializing in ultra-pure cannabinoid distillates. Their vape oils utilize proprietary CO2 extraction and nanoemulsion technologies for enhanced bioavailability.

Innovation Highlights:

  • Patented THC remediation process (0.0% THC guarantee)

  • FDA-registered manufacturing facility

  • Military and first responder wellness programs

Download FREE Sample Report: Global CBD Vape Oil Market – View in Detailed Research Report


9️⃣ 2. CW Hemp/CW Botanicals

Headquarters: Boulder, Colorado, USA
Key Offering: Charlotte’s Web CBD Vape Oils

As the pioneer behind the famous Charlotte’s Web strain, CW Hemp offers premium CBD vape products with consistent dosing and proprietary hemp genetics.

Innovation Highlights:

  • Seed-to-sale tracking with blockchain technology

  • Clinical research partnerships with major universities


8️⃣ 3. Freedom Leaf

Headquarters: Nevada, USA
Key Offering: Ilera CBD Vape Products

Freedom Leaf operates one of the most advanced cannabinoid processing facilities in the U.S., supplying vape-ready CBD distillates to white-label and retail markets.

Innovation Highlights:

  • Organic hemp cultivation practices

  • Multi-state manufacturing footprint


7️⃣ 4. Green Roads

Headquarters: Florida, USA
Key Offering: Pharmacist-Formulated CBD Vape Oils

Green Roads sets industry standards with pharmacist-developed formulations and rigorous third-party testing protocols for all vape products.

Innovation Highlights:

  • Precise milligram-per-dose formulations

  • 40+ cannabinoid profile testing

Download FREE Sample Report: Global CBD Vape Oil Market – View in Detailed Research Report


6️⃣ 5. Medical Marijuana, Inc.

Headquarters: California, USA
Key Offering: HempMeds® CBD Vape Products

This publicly traded company focuses on medical-grade CBD with international distribution networks spanning 40+ countries.

Innovation Highlights:

  • First company to legally export CBD products internationally

  • GACP-certified hemp cultivation


5️⃣ 6. Folium Biosciences

Headquarters: Colorado, USA
Key Offering: Bulk CBD Vape Oils

As North America’s largest vertically integrated hemp producer, Folium supplies high-volume CBD distillates to vape manufacturers globally.

Innovation Highlights:

  • 25,000-acre organic hemp cultivation

  • EU-GMP certified manufacturing


4️⃣ 7. ENDOCA

Headquarters: Netherlands
Key Offering: Organic CBD Vape Cartridges

ENDOCA maintains complete supply chain control from Dutch organic farms to CO2-extracted vape formulations meeting pharmaceutical standards.

Innovation Highlights:

  • Cold extraction technology preserving terpenes

  • Certified B Corporation


3️⃣ 8. Canopy Growth Corporation

Headquarters: Ontario, Canada
Key Offering: Spectrum Therapeutics CBD Vapes

This cannabis giant leverages its extensive R&D capabilities to produce science-backed CBD vape products with precise cannabinoid ratios.

Innovation Highlights:

  • Cannabis research partnerships with 30+ universities

  • GxP-compliant facilities


2️⃣ 9. Aphria/ Tilray Brands

Headquarters: Ontario, Canada
Key Offering: RIFF CBD Vape Products

The merged entity combines Aphria’s extraction expertise with Tilray’s global distribution network, producing premium CBD vape formulations.

Innovation Highlights:

  • EU-GMP and FDA-approved facilities

  • Clinical trial participation


1️⃣ 10. CBD American Shaman

Headquarters: Kansas City, MO, USA
Key Offering: Water-Soluble CBD Vape Oils

Their proprietary nanotechnology creates vape oils with significantly higher absorption rates compared to conventional CBD vape products.

Innovation Highlights:

  • 9x increased bioavailability technology

  • 500+ franchised retail locations

Get Full Report Here: Global CBD Vape Oil Market – View in Detailed Research Report


🌿 Market Outlook: The Future of CBD Vaping

The CBD vape oil sector is moving toward pharmaceutical-grade standards, with increasing regulatory oversight and consumer demand for lab-verified products. While the market currently focuses on North America and Europe, Asia-Pacific is emerging as the next growth frontier.

📈 Key Industry Trends:

  • Shift toward isolate-based formulations for consistent dosing

  • Growing adoption of pod-based CBD vaporizers

  • Increasing GMP certification requirements

  • Expansion of medical cannabis programs incorporating CBD vapes

Get Full Report Here: Global CBD Vape Oil Market – View in Detailed Research Report

The profiled companies are not only meeting current market needs—they’re actively shaping the future of cannabinoid wellness through research, technology, and quality innovation.