The Global 2-Fluoropyridine Market was valued at USD 112.3 Million in 2024 and is projected to reach USD 156.7 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 5.7% during the forecast period (2024–2030). This chemical intermediate’s vital role in pharmaceutical synthesis and crop protection formulations is creating sustained demand across North America, Europe, and Asia-Pacific markets.
With fluorine’s unique properties enhancing molecular performance in active pharmaceutical ingredients (APIs) and agricultural chemicals, specialized manufacturers are scaling production while maintaining exceptional purity standards. This analysis highlights the Top 10 Companies in the 2-Fluoropyridine Industry, featuring technology leaders and regional suppliers driving innovation in fluorine chemistry.
🔟 1. Fuxin Yongduo Chemical
Headquarters: Fuxin, China
Key Offering: Pharmaceutical & Agrochemical Grade 2-FP (98%-99.9%)
As China’s dominant fluoropyridine producer, Fuxin Yongduo operates dedicated production lines meeting stringent international standards. Their integrated fluorination technology ensures competitive pricing for bulk pharmaceutical customers.
Production Advantages:
- 800MT annual capacity with 95% utilization rate
- Halogen exchange reactor technology reduces byproducts
- Pharma-grade batches with <1ppm heavy metals
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9️⃣ 2. Fuxin XINKAIDA Fluorine Chemistry
Headquarters: Fuxin, China
Key Offering: Ultra-Pure 2-Fluoropyridine (≥99.95%)
Specializing in high-value fluorochemicals, XINKAIDA supplies multinational pharmaceutical firms through validated quality systems. Their continuous distillation process achieves exceptional purity for sensitive drug syntheses.
Technical Specifications:
- Residual solvents <100ppm by GC analysis
- Particle size control (10-50μm available)
- Stable isotopic forms (13C, 15N labeled)
8️⃣ 3. Changzhou Huanan Chemical
Headquarters: Changzhou, China
Key Offering: Custom Fluoropyridine Derivatives
With two decades of heterocyclic chemistry expertise, Changzhou Huanan provides tailored fluorinated building blocks for drug discovery programs and specialty material applications.
Innovation Capabilities:
- 15+ fluoropyridine analogs in regular production
- Metal-catalyzed fluorination pilot plant
- Process development for novel fluorinated APIs
7️⃣ 4. Capot Chemical
Headquarters: Hangzhou, China
Key Offering: Electronic Grade 2-Fluoropyridine
Capot’s semiconductor-grade fluorochemicals meet the exacting requirements of OLED and photovoltaic material manufacturers through precision purification technologies.
Quality Systems:
- Class 10,000 cleanroom packaging
- ICP-MS certified <0.1ppb metal content
- Moisture-controlled argon packaging
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6️⃣ 5. Zhejiang Xingsheng Technology
Headquarters: Zhejiang, China
Key Offering: Cost-Optimized Industrial Quantities
Xingsheng’s fully automated plant delivers price-competitive 2-fluoropyridine for large-scale agrochemical production through innovative continuous flow chemistry.
Operational Metrics:
- 5,000MT total fluorine compound capacity
- Zero liquid discharge water treatment
- On-site hydrogen fluoride production
5️⃣ 6. Jiangsu Wanlong Chemical
Headquarters: Jiangsu, China
Key Offering: Research-Grade Fluoropyridines
Wanlong serves academic and industrial researchers with specialty fluorinated compounds, including chiral auxiliaries and isotopically labeled materials.
Specialty Portfolio:
- Deuterated 2-fluoropyridine-d4
- N-methyl-2-fluoropyridinium salts
- Fluoropyridine boronic esters
4️⃣ 7. Hubei Norna Technology
Headquarters: Wuhan, China
Key Offering: cGMP Certified 2-FP
Norna’s FDA-inspected facility produces pharmaceutical intermediates under current Good Manufacturing Practices for regulated markets.
Regulatory Status:
- EDMF/ASMF dossier available
- US DMF #35742 (Type II)
- Stability data through ICH conditions
3️⃣ 8. Haihang Industry
Headquarters: Jinan, China
Key Offering: Global Distribution Network
This chemical supply chain specialist maintains strategic inventories of 2-fluoropyridine in North America, Europe, and Asia for just-in-time delivery.
Logistics Infrastructure:
- REACH/OSHA compliant warehouses
- Temperature-controlled transport
- 24/7 emergency response teams
2️⃣ 9. Vivitide
Headquarters: Massachusetts, USA
Key Offering: Small-Scale API Intermediates
Vivitide bridges the gap between research and production with gram-to-kilogram quantities of fluorinated pyridines for preclinical development.
Client Services:
- Process chemistry support
- Regulatory starting materials
- GMP-like documentation packages
1️⃣ 10. Tokyo Chemical Industry (TCI)
Headquarters: Tokyo, Japan
Key Offering: Ultra-High Purity Reagents
TCI’s analytical-grade 2-fluoropyridine sets global quality benchmarks for pharmaceutical analytical testing and formulation development.
Quality Leadership:
- ≥99.99% purity by quantitative NMR
- Gas chromatography-mass spectrometry profiles
- Strict oxygen/moisture exclusion protocols
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🔬 Market Dynamics: Fluorine Chemistry Driving Next-Gen Formulations
The 2-fluoropyridine sector reflects broader trends in fluorine incorporation, with drug developers increasingly utilizing fluorinated building blocks to enhance potency and metabolic stability.
📊 Growth Accelerators:
- 65% of new small molecule drugs contain fluorine (2023 data)
- Agrochemical sector adopting fluoropyridine motifs for new actives
- Asia-Pacific capacity expanding at 7.2% annually through 2030
- Patent expiries driving generic API production
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Global 2-Fluoropyridine Market – View in Detailed Research Report
The market leaders profiled above are enabling critical advancements across life sciences and advanced materials through their fluorochemical expertise and manufacturing capabilities.