Top 10 Companies in the Global and United States Calcium Phosphate Based Ceramic Market (2025): Pioneering Biomaterial Innovations for Orthopedic and Dental Applications

In Business Insights
July 01, 2025

The Global Calcium Phosphate Based Ceramic Market was valued at USD 1.2 Billion in 2024 and is projected to reach USD 2.3 Billion by 2032, growing at a Compound Annual Growth Rate (CAGR) of 8.5% during the forecast period (2024–2032). This robust growth stems from increasing demand for bone graft substitutes, rising dental implant procedures, and technological advancements in bioactive ceramic formulations that enhance osseointegration.


🔟 1. Evonik Industries AG

Headquarters: Essen, Germany
Key Offering: VITOSSO® Bone Graft Substitutes

Evonik dominates the calcium phosphate ceramics sector with its clinically proven bone void fillers and dental regeneration materials. Their patented BONITmatrix® technology demonstrates superior osteoconductivity through precisely engineered porosity and crystallinity.

Clinical Advantages:

  • 3D printed custom implants with patient-specific geometries

  • Nanotextured surfaces that accelerate bone growth by 40% versus standard materials

  • Strategic collaborations with 15+ academic medical centers for clinical validation

Download FREE Sample Report: Global and United States Calcium Phosphate Based Ceramic Market – View in Detailed Research Report


9️⃣ 2. CeramTec GmbH

Headquarters: Plochingen, Germany
Key Offering: BIOLOX® Advanced Ceramic Implants

CeramTec specializes in high-performance medical ceramics, with FDA-cleared calcium phosphate formulations for spinal fusion and joint reconstruction that achieve 92% clinical success rates at five-year follow-ups.

Clinical Advantages:

  • Antimicrobial ceramic composites reduce post-op infection rates by 60%

  • Multiphase ceramics mimic natural bone’s mechanical properties


8️⃣ 3. Stryker Corporation

Headquarters: Kalamazoo, Michigan, USA
Key Offering: Tritanium® Porous Implant Technology

Stryker’s FDA-approved titanium-calcium phosphate composites demonstrate 15% faster radiographic fusion compared to traditional PEEK implants in spinal applications, with over 500,000 successful clinical cases.

Clinical Advantages:

  • 3D printed β-TCP scaffolds with controlled degradation profiles

  • Surface modifications that enhance protein adsorption and cell attachment

Download FREE Sample Report: Global and United States Calcium Phosphate Based Ceramic Market – View in Detailed Research Report


7️⃣ 4. Kyocera Corporation

Headquarters: Kyoto, Japan
Key Offering: AWP® Nanostructured Coatings

Kyocera’s atomic-layer-deposited hydroxyapatite coatings achieve 97% crystallinity and increase bone-implant contact area by 35% in loaded dental applications, with clinical data showing 99% 10-year survival rates.

Clinical Advantages:

  • Sub-micron thickness control across complex implant geometries

  • Asia’s most advanced bioceramic manufacturing facilities (ISO 13485 certified)


6️⃣ 5. Nobel Biocare (Envista Holdings)

Headquarters: Yorba Linda, California, USA
Key Offering: NobelParallel™ Ceramic Implant Systems

Nobel Biocare’s fluoride-modified calcium phosphate surface treatments demonstrate 30% greater bone-to-implant contact at 6 weeks post-op compared to standard titanium implants in multicenter clinical trials.

Clinical Advantages:

  • OsseoSpeed™ surface chemistry accelerates osteoblast activity

  • Integrated digital workflow for precise ceramic restorations


5️⃣ 6. Zimmer Biomet Holdings, Inc.

Headquarters: Warsaw, Indiana, USA
Key Offering: trabecular metal-ceramic composites

Zimmer Biomet’s porous tantalum-calcium phosphate constructs demonstrate 80% bone ingrowth at 12 weeks in load-bearing applications, with mechanical properties matching cancellous bone.

Clinical Advantages:

  • Surface microtextures that guide osteoblast migration

  • Ionic substitutions that stimulate mesenchymal stem cell differentiation

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