The Global N-glycanase Market was valued at USD 85 million in 2024 and is projected to reach USD 115 million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 5.2% during the forecast period (2024–2030). This expansion is driven by rising demand for biopharmaceutical characterization, increasing therapeutic monoclonal antibody production, and advancements in glycobiology research tools.

As the biopharmaceutical industry prioritizes protein quality control and glycan analysis, N-glycanase enzymes have become indispensable for therapeutic development. This report examines the Top 10 Companies in the N-glycanase Industry—innovators shaping the future of glycoprotein research and biomanufacturing quality control.

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🔟 1. Sunson Industry Group

Headquarters: Beijing, China
Key Offering: Industrial-grade N-glycanase, Glycoanalysis Solutions

Sunson has emerged as China’s leading enzyme manufacturer, specializing in cost-effective N-glycanase formulations for large-scale bioprocessing applications.

Technical Advantages:

• High-yield microbial expression systems
• Thermostable enzyme variants
• GMP-compliant production facilities

Download FREE Sample Report:
Global N-glycanase Market – View in Detailed Research Report

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9️⃣ 2. New England Biolabs

Headquarters: Ipswich, Massachusetts, USA
Key Offering: PNGase F, GlykoPrep Kits

NEB sets the gold standard for research-grade N-glycanase, with enzymes trusted by academic and pharmaceutical laboratories worldwide.

Technical Advantages:

• Ultra-pure, protease-free formulations
• Optimized for mass spectrometry workflows
• Comprehensive technical validation data

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8️⃣ 3. Agilent Technologies (ProZyme)

Headquarters: Santa Clara, California, USA
Key Offering: GlycanRelease Kits, Automated Solutions

Agilent’s acquisition of ProZyme has created a powerhouse in glycoprotein analysis instrumentation and reagents.

Technical Advantages:

• HPLC/MS compatible formulations
• High-throughput workflow integration
• cGMP quality systems

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7️⃣ 4. Merck KGaA (Sigma-Aldrich)

Headquarters: Darmstadt, Germany
Key Offering: PNGase A & F, Glycobiology Research Suite

Merck’s life science division provides comprehensive glycoprotein research tools, serving both academic and industrial markets.

Technical Advantages:

• Animal-component free production
• Global distribution network
• Technical support specialists

Download FREE Sample Report:
Global N-glycanase Market – View in Detailed Research Report

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6️⃣ 5. Thermo Fisher Scientific

Headquarters: Waltham, Massachusetts, USA
Key Offering: Rapid PNGase F, Glycan Labeling Systems

Thermo Fisher delivers complete N-glycan analysis solutions through its extensive portfolio of reagents and instruments.

Technical Advantages:

• Integrated mass spec compatibility
• Fast 15-minute deglycosylation
• Regulatory support documentation

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5️⃣ 6. Takara Bio

Headquarters: Shiga, Japan
Key Offering: Endo F Series, Glycan Mapping Kits

Takara Bio specializes in enzymatic solutions for Asian biopharmaceutical markets, with customized stabilization for regional needs.

Technical Advantages:

• Specific glycan linkage cleavage
• Optimized for humidity-sensitive regions
• Bilingual technical support

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4️⃣ 7. Bio-Techne (BioVision)

Headquarters: Minneapolis, Minnesota, USA
Key Offering: ELISA-Compatible PNGase, Glycan Standards

Bio-Techne’s BioVision division focuses on antibody-compatible deglycosylation reagents for immunology research.

Technical Advantages:

• Epitope preservation technology
• High-sensitivity detection systems
• Antibody pairing guidance

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3️⃣ 8. QA-Bio

Headquarters: Palm Desert, California, USA
Key Offering: cGMP Glycan Release Systems

QA-Bio specializes in quality control solutions for commercial biomanufacturing, with regulatory-ready documentation.

Technical Advantages:

• Validation packages for FDA submissions
• Lot-to-lot consistency protocols
• Biotherapeutic-specific formulations

Download FREE Sample Report:
Global N-glycanase Market – View in Detailed Research Report

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2️⃣ 9. Genovis

Headquarters: Lund, Sweden
Key Offering: SmartEnzymes, Glycan Analysis Platform

Genovis develops innovative enzyme engineering solutions for challenging glycoprotein characterization needs.

Technical Advantages:

• Site-specific cleavage variants
• Automated platform compatibility
• Antibody-focused applications

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1️⃣ 10. Shenqiu Biotechnology

Headquarters: Henan, China
Key Offering: Value-Priced Research Enzymes

Shenqiu Biotech provides affordable N-glycanase options for academic and emerging market researchers.

Technical Advantages:

• Competitive pricing structure
• Custom molecular weight options
• Rapid order fulfillment

Get Full Report Here:
Global N-glycanase Market – View in Detailed Research Report

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🔬 Market Outlook: Evolving Needs in Glycoprotein Analysis

The N-glycanase sector is adapting to new challenges in biotherapeutic development, with increasing demand for:

📈 Key Industry Trends:

• High-throughput glycan profiling for biosimilar development
• Automated sample preparation solutions
• Advanced characterization of complex glycoproteins
• Regulatory-compliant quality control systems

These market leaders are enabling breakthroughs across precision medicine, vaccine development, and next-generation biologics through innovative glycoprotein analysis solutions.

Get Full Report Here:
Global N-glycanase Market – View in Detailed Research Report