The Global 3D Biological Printing Market was valued at USD 1.56 Billion in 2024 and is projected to reach USD 3.24 Billion by 2030, growing at a Compound Annual Growth Rate (CAGR) of 12.9% during the forecast period (2024-2030). This rapid expansion is driven by advancements in regenerative medicine, increasing pharmaceutical R&D investments, and growing adoption of personalized medicine approaches.
As the healthcare sector embraces bioprinting’s revolutionary potential, industry leaders are developing innovative technologies to create functional human tissues, advanced drug testing platforms, and customized medical solutions. This report profiles the Top 10 Companies in the 3D Biological Printing Industry – a combination of established market leaders and emerging innovators shaping the future of medical science.
🔟 1. Organovo Holdings, Inc.
Headquarters: San Diego, California, USA
Key Offering: NovoGen Bioprinting Platform, ExVive Human Tissues
A pioneer in 3D bioprinting since 2007, Organovo specializes in creating functional human tissues for pharmaceutical research and therapeutic applications. Their patented NovoGen platform enables precise spatial arrangement of multiple cell types to generate architecturally accurate tissue structures.
Technology Highlights:
- First FDA-cleared 3D bioprinted liver tissue for preclinical drug testing
- Strategic collaborations with 8 of top 15 pharmaceutical companies
- Advanced vascularized tissue models for transplant research
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9️⃣ 2. CELLINK (BICO Group)
Headquarters: Gothenburg, Sweden
Key Offering: BIO X, LUMEN X, ECM-based Bioinks
Since its 2016 founding, CELLINK has become a global bioprinting solutions provider now operating under BICO Group. The company offers an integrated ecosystem including bioprinters, bioinks, and software solutions serving over 1,500 research institutions worldwide.
Technology Highlights:
- Pioneered universal bioink technology compatible with multiple cell types
- Industry-leading multi-material bioprinting capabilities
- Expanding into automated cell culture and analysis systems
8️⃣ 3. Allevi (3D Systems)
Headquarters: Philadelphia, Pennsylvania, USA
Key Offering: Allevi Bioprinters, Tissue Kits, Bioprinting Software
Acquired by 3D Systems in 2021, Allevi provides accessible bioprinting solutions to research institutions and pharmaceutical companies. Their platform enables researchers to design and print complex 3D tissues with micron-level precision.
Technology Highlights:
- Intuitive bioprinting software with drag-and-drop functionality
- Specialized bioinks for cardiac, neural, and musculoskeletal tissues
- Seamless integration with 3D Systems’ manufacturing expertise
7️⃣ 4. EnvisionTEC (Desktop Metal)
Headquarters: Gladbeck, Germany
Key Offering: 3D-Bioplotter Series, Medical-grade Bioprinters
Now part of Desktop Metal, EnvisionTEC delivers high-precision bioprinters used in both research and clinical settings. Their 3D-Bioplotter systems have become an industry standard for extrusion-based bioprinting applications.
Technology Highlights:
- Multiple FDA-cleared medical bioprinting systems
- Broad material compatibility including polymers and bioceramics
- Custom configurations for diverse research applications
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6️⃣ 5. Regemat 3D
Headquarters: Granada, Spain
Key Offering: BioV1, REG4LIFE, Custom Bioprinters
Regemat 3D specializes in modular bioprinting platforms focused on regenerative medicine applications. Their flexible systems allow customization to specific tissue engineering requirements across academic and clinical settings.
Technology Highlights:
- Pioneered commercial bioprinting in Southern Europe
- Open-source approach encourages collaborative development
- Strong emphasis on clinical translation solutions
5️⃣ 6. Advanced Solutions Life Sciences
Headquarters: Louisville, Kentucky, USA
Key Offering: BioAssemblyBot, TSIM Software
Advanced Solutions transformed bioprinting with their six-axis robotic BioAssemblyBot platform, enabling complex tissue vascularization and 3D tissue modeling capabilities beyond conventional systems.
Technology Highlights:
- First unified hardware/software bioprinting platform
- Tissue Structure Information Modeling (TSIM) software
- Developing implantable human organ constructs
4️⃣ 7. FluidForm
Headquarters: Acton, Massachusetts, USA
Key Offering: FRESH Technology, LifeSupport Bioinks
FluidForm innovated the FRESH (Freeform Reversible Embedding of Suspended Hydrogels) printing method, enabling fabrication of delicate tissue structures not possible with traditional bioprinting approaches.
Technology Highlights:
- NIH-funded technology development
- Created functional beating cardiac tissue constructs
- Extensive patent portfolio in advanced bioprinting
3️⃣ 8. Cyfuse Biomedical
Headquarters: Tokyo, Japan
Key Offering: Regenova 3D Bioprinter, Kenzan Method
This Japanese innovator developed the unique Kenzan technique using needle arrays to position cell spheroids that fuse into scaffold-free tissue structures – a fundamentally different approach to bioprinting.
Technology Highlights:
- Only scaffold-free 3D tissue construction technology
- Ongoing clinical trials for 3D printed vascular grafts
- Dominant position in Asian bioprinting markets
2️⃣ 9. Poietis
Headquarters: Pessac, France
Key Offering: NGB-R Bioprinter, Laser Assisted Bioprinting
Poietis specializes in high-resolution laser-assisted bioprinting (LAB), achieving single-cell precision for creating complex tissue architectures with multiple cell types – critical for advanced research applications.
Technology Highlights:
- European leader in LAB precision technology
- Proprietary 4D bioprinting capability
- Focus on advanced skin tissue models
1️⃣ 10. Brinter
Headquarters: Turku, Finland
Key Offering: Modular Bioprinting Platform, Multi-head Systems
Brinter delivers modular, customizable bioprinting solutions designed for both research and industrial-scale applications, emphasizing scalability, reliability, and ease of automation.
Technology Highlights:
- Hybrid multi-technology printing approaches
- GMP-compliant systems for clinical manufacturing
- Industrial-grade design for production environments
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Global 3D Biological Printing Market – View in Detailed Research Report
🔬 Outlook: The Future of 3D Biological Printing Is Complex and Automated
The 3D biological printing industry is rapidly evolving from research laboratories to clinical applications and industrial-scale production. While tissue models dominate current uses, the field is progressing toward functional organ printing and personalized medicine solutions at an accelerated pace.
🧪 Key Trends Transforming the Market:
- Growing pharmaceutical adoption for drug discovery and toxicology testing
- Advancements in vascularization and perfusion techniques
- Development of patient-specific implants and prosthetics
- Integration of AI and machine learning in bioprinting processes
- Expansion into microgravity bioprinting research
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Global 3D Biological Printing Market – View in Detailed Research Report
The featured companies represent more than just bioprinter manufacturers – they’re enabling a fundamental transformation in medical research, therapeutic development, and ultimately, patient care worldwide.
