Top 10 Companies in the Global Sodium Acetylated Hyaluronate Market (2025): Innovation Leaders Driving Cosmetic & Pharmaceutical Advancements

In Business Insights
June 11, 2025

The Global Sodium Acetylated Hyaluronate Market was valued at USD 124.7 Million in 2023 and is projected to reach USD 205.3 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 7.4% during the forecast period (2024-2030). This growth is driven by increasing demand for advanced skincare solutions, anti-aging products, and specialized medical applications of this modified hyaluronic acid derivative.

As the cosmetics and pharmaceutical industries increasingly prioritize bioactive ingredients with enhanced performance characteristics, sodium acetylated hyaluronate has emerged as a premium ingredient in high-end formulations. In this analysis, we examine the Top 10 Companies in the Sodium Acetylated Hyaluronate Market—including biotechnology innovators, specialty chemical producers, and cosmetic ingredient specialists.


🔟 1. FreShine Chemicals Company

Headquarters: Zhengzhou, China
Key Offering: Pharmaceutical & Cosmetic Grade Sodium Acetylated Hyaluronate

A pioneer in hyaluronic acid derivatives, FreShine Chemicals manufactures high-purity sodium acetylated hyaluronate with molecular weights ranging from 800kDa to 2.4MDa. Their patented acetylation process enhances the molecule’s skin adhesion and moisture retention properties.

Innovation Highlights:

  • GMP-certified fermentation and purification facilities

  • Customizable molecular weight distributions

  • Strategic supply agreements with global cosmetic brands

Download FREE Sample Report: Global Sodium Acetylated Hyaluronate Market – View in Detailed Research Report


9️⃣ 2. Bloomage BioTechnology Corporation Limited

Headquarters: Jinan, China
Key Offering: AcHA (Acetylated Hyaluronic Acid Sodium Salt)

Bloomage leads the global hyaluronic acid market with vertically integrated production. Their acetylated formulation demonstrates superior stability and prolonged cutaneous residence time compared to conventional HA.

Innovation Highlights:

  • Proprietary bacterial fermentation technology

  • Annual production capacity of 330 metric tons


8️⃣ 3. Anward

Headquarters: Carlsbad, California, USA
Key Offering: Ultra-Low Molecular Weight AcHA (10-50kDa)

Anward specializes in cosmetic-grade acetylated HA optimized for transdermal delivery. Their low molecular weight variants penetrate the skin barrier more effectively while maintaining moisture retention.

Innovation Highlights:

  • Bioactive fragment synthesis technology

  • FDA-compliant cGMP manufacturing


7️⃣ 4. AbaChemScene

Headquarters: Monmouth Junction, New Jersey, USA
Key Offering: Research-Grade AcHA for Pharmaceutical Development

AbaChemScene supplies high-purity acetylated HA for drug delivery research and medical applications, supporting clinical trials in ophthalmology and dermatology treatments.

Innovation Highlights:

  • Custom chemical modifications services

  • Consistent batch-to-batch performance

Download FREE Sample Report: Global Sodium Acetylated Hyaluronate Market – View in Detailed Research Report


6️⃣ 5. Alfa Chemistry

Headquarters: New York, USA
Key Offering: Pharmaceutical Intermediates with AcHA

Alfa Chemistry develops acetylated HA solutions engineered for controlled drug release applications, particularly in transdermal patches and injectable formulations.

Innovation Highlights:

  • GMP-grade biocompatibility testing

  • Sterile fill-finish capabilities


5️⃣ 6. MolPort

> Riga, Latvia
Key Offering: Synthetic AcHA Building Blocks

This European chemical supplier provides molecular components for acetylated HA synthesis, serving cosmetic formulators with customized solutions.

Innovation Highlights:

  • Structure-activity relationship expertise

  • Adjustable acetylation degrees (10%-95%)


4️⃣ 7. BLD Pharm

Headquarters: Shanghai, China
Key Offering: AcHA-Polymer Conjugates

BLD Pharm develops advanced acetylated HA derivatives combined with biocompatible polymers for specialized medical and cosmetic applications.

Innovation Highlights:

  • Crosslinked hydrogel technologies

  • Temperature-responsive formulations


3️⃣ 8. HAORS Chem

Headquarters: Hangzhou, China
Key Offering: Low-Endotoxin AcHA for Injectable Use

HAORS Chem specializes in medical-grade acetylated HA meeting stringent pharmacopeia standards for aesthetic medicine and ophthalmic applications.

Innovation Highlights:

  • Certified sterile production

  • Custom rheology profiles


2️⃣ 9. Wuhan Fortuna Chemical Co., Ltd

Headquarters: Wuhan, China
Key Offering: Cost-Competitive AcHA for Mass Market

Fortuna Chemical provides affordable acetylated HA variants for mainstream skincare products while maintaining pharmaceutical-grade quality standards.

Innovation Highlights:

  • Large-scale fermentation capacity

  • Sustainable production methods

Download FREE Sample Report: Global Sodium Acetylated Hyaluronate Market – View in Detailed Research Report


1️⃣ 10. Bioberica S.A.U.

Headquarters: Barcelona, Spain
Key Offering: Medical Device & Nutraceutical AcHA

This European biotechnology firm develops acetylated HA formulations specifically for orthopedic and wound healing applications, leveraging extended residence time.

Innovation Highlights:

  • OSTENIL® product line for joint health

  • CE-marked medical devices

Get Full Report Here: Global Sodium Acetylated Hyaluronate Market – View in Detailed Research Report


🔬 Outlook: Sodium Acetylated Hyaluronate’s Expanding Applications

The sodium acetylated hyaluronate market is evolving beyond traditional moisturizing benefits, with new biomedical uses and advanced delivery platforms emerging.

📈 Key Market-Shaping Trends:

  • Development of “smart” acetylated HA with environmental responsiveness

  • Growing adoption in microneedle delivery systems

  • Expansion into cartilage repair and wound healing applications

  • Increasing preference in premium anti-aging formulations

Get Full Report Here: Global Sodium Acetylated Hyaluronate Market – View in Detailed Research Report

The companies profiled above are not only supplying high-performance ingredients—they’re actively defining the future of skincare science and therapeutic biomaterials.