The Global 1,2,4-Trifluorobenzene Market was valued at USD 145.6 Million in 2024 and is projected to reach USD 198.4 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 5.3% during the forecast period (2024-2030). This growth is primarily driven by increasing pharmaceutical applications, agrochemical sector expansion, and rising demand for high-purity fluorinated compounds in advanced materials.
As the specialty chemicals industry evolves with stricter quality requirements and environmental regulations, key manufacturers are delivering the molecular building blocks for next-generation pharmaceuticals. In this report, we profile the Top 10 Companies in the 1,2,4-Trifluorobenzene Industry—specialized chemical producers enabling drug discovery and advanced material applications.
🔟 1. Zhejiang Jitai New Materials Co., Ltd.
Headquarters: Zhejiang, China
Key Offering: 99% Purity 1,2,4-Trifluorobenzene
As the largest Chinese producer of fluorinated aromatic compounds, Zhejiang Jitai operates dedicated production lines with a combined annual capacity exceeding 1,200 metric tons. The company supplies pharmaceutical companies across Asia, Europe and North America.
Technical Capabilities:
- Halogen exchange reaction technology
- Pharmaceutical-grade distillation systems
- GMP-compliant analytical testing
Download FREE Sample Report: Global 1,2,4-Trifluorobenzene Market – View in Detailed Research Report
9️⃣ 2. Zhejiang Xieshi New Materials Co., Ltd.
Headquarters: Zhejiang, China
Key Offering: Technical & Pharmaceutical Grade Products
Specializing in fluorination processes, Xieshi New Materials has vertically integrated production from raw materials to finished 1,2,4-Trifluorobenzene. Their proprietary purification methods ensure batch-to-batch consistency required by pharmaceutical customers.
Technical Capabilities:
- Continuous flow manufacturing
- Low-temperature fluorination technology
8️⃣ 3. Zhejiang Zhongxin Fluorine Materials Co., Ltd.
Headquarters: Zhejiang, China
Key Offering: 98-99% Purity Grades
With 15+ years of fluorochemical expertise, Zhongxin supplies European and Indian pharmaceutical markets. The company has invested significantly in solvent recovery systems to improve sustainability.
Technical Capabilities:
- Closed-loop production processes
- Waste minimization protocols
7️⃣ 4. Capot Chemical Co., Ltd.
Headquarters: Zhejiang, China
Key Offering: Ultra-High Purity Intermediates
Capot Chemical’s 800 metric ton annual production capacity serves regulated pharmaceutical markets. Their quality systems meet FDA and EMA standards for impurity control.
Technical Capabilities:
- Trace metal analysis capabilities
- Stable isotope labeling services
Download FREE Sample Report: Global 1,2,4-Trifluorobenzene Market – View in Detailed Research Report
6️⃣ 5. Huaian Dongsheng Chemical Co., Ltd.
Headquarters: Jiangsu, China
Key Offering: Industrial & Pharmaceutical Grades
Dongsheng Chemical has developed specialized halogen exchange reactors that improve yield and purity in 1,2,4-Trifluorobenzene production. Their technical team supports custom synthesis projects.
Technical Capabilities:
- Catalyst development expertise
- Process intensification technologies
5️⃣ 6. Shanghai Huayi Chemical Co., Ltd.
Headquarters: Shanghai, China
Key Offering: Specialty Fluorochemicals
Huayi Chemical provides analytical method development alongside their product offerings, helping pharmaceutical clients meet regulatory submission requirements.
Technical Capabilities:
- Impurity identification services
- Structure elucidation expertise
4️⃣ 7. Chemieliva Pharmaceutical Co., Ltd.
Headquarters: Wuhan, China
Key Offering: API Intermediates
With dual expertise in chemistry and pharmaceutics, Chemieliva delivers building blocks that meet pharmacopeial standards for drug development.
Technical Capabilities:
- Process validation support
- Regulatory documentation packages
3️⃣ 8. Shanghai Yixin Chemical Co., Ltd.
Headquarters: Shanghai, China
Key Offering: Contract Fluorination Services
Yixin’s modular production facility enables flexible batch sizes from laboratory to commercial scale, supporting customers through all development phases.
Technical Capabilities:
- Kilogram-scale cGMP production
- Process safety evaluations
Read Full Report: Global 1,2,4-Trifluorobenzene Market – View in Detailed Research Report
2️⃣ 9. Manus Aktteva Biopharma LLP
Headquarters: Gujarat, India
Key Offering: Regulated Market Intermediates
This Indian manufacturer combines Western regulatory expertise with cost-effective production capabilities serving global pharmaceutical clients.
Technical Capabilities:
- FDA/EMA compliance support
- Quality by Design approaches
1️⃣ 10. Fluoropharm Chemical Co., Ltd.
Headquarters: Jiangsu, China
Key Offering: Specialty Fluorination Solutions
Fluoropharm’s exclusive focus on fluorochemicals enables deep technical expertise in challenging synthesis routes for pharmaceutical applications.
Technical Capabilities:
- Electrophilic fluorination methods
- Process analytical technology
Download FREE Sample Report: Global 1,2,4-Trifluorobenzene Market – View in Detailed Research Report
🔬 Market Outlook: Pharmaceutical Demand Driving Expansion
The 1,2,4-Trifluorobenzene market is poised for steady growth, with pharmaceutical applications accounting for 60% of consumption. The compound’s unique properties make it invaluable for developing improved drug candidates with enhanced metabolic stability and membrane permeability.
📈 Key Industry Trends:
- Growing adoption in protease inhibitors and kinase modulators
- Increasing complexity of drug molecules requiring specialized intermediates
- Tighter regulatory scrutiny of impurities in pharmaceutical synthesis
- Expansion of manufacturing capabilities in India and China
Read Full Report: Global 1,2,4-Trifluorobenzene Market – View in Detailed Research Report
The companies profiled represent the backbone of pharmaceutical chemical supply chains, enabling the development of life-changing medications through their specialized expertise in fluorinated compounds production.
