Top 10 Companies in the Macrocyclic Musks for Cosmetics Industry (2025): Fragrance Innovators Shaping Sustainable Perfumery

In Business Insights
June 08, 2025

The Global Macrocyclic Musks for Cosmetics Market was valued at USD 184 million in 2023 and is projected to reach USD 299.35 million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 7.20% during the forecast period (2023-2030). This expansion is driven by tightening regulations on nitro musks, growing consumer demand for long-lasting fragrances, and the beauty industry’s shift toward sustainable ingredient sourcing.

As perfume houses and personal care brands reformulate products to meet environmental standards, macrocyclic musks have become the preferred choice for their exceptional stability and biodegradability. This report examines the Top 10 Companies in the Macrocyclic Musks for Cosmetics Industry—specialty chemical firms and fragrance houses leading the market through technological innovation and eco-conscious production.


🔟 1. International Flavors & Fragrances Inc. (IFF)

Headquarters: New York, USA
Key Offering: Exaltolide®, Globalide®, Musk Ketone Derivatives

IFF dominates 28% of the global macrocyclic musk market, supplying premium fragrance compounds to 78% of prestige perfumery brands. The company’s biotech-derived musks achieve 140% greater tenacity than conventional alternatives while reducing environmental persistence by 92%.

Industry Leadership:

  • Pioneered the first enzymatic musk synthesis platform (2021)

  • Strategic acquisition of Fragrance Resources (2023) expanding portfolio

  • $650 million R&D investment in green chemistry since 2020

Download FREE Sample Report: Macrocyclic Musks for Cosmetics Market – View in Detailed Research Report


9️⃣ 2. Firmenich SA

Headquarters: Geneva, Switzerland
Key Offering: Habanolide®, Ethylene Brassylate, Cyclopentadecanolide

Firmenich leads European macrocyclic musk production with six dedicated synthesis facilities generating 15,000 metric tons annually. Its patented molecular encapsulation technology extends fragrance longevity by up to 36 hours while meeting the strictest IFRA standards.

Industry Leadership:

  • Developed carbon-neutral musk production process (2022)

  • Exclusive supplier to 32 luxury fragrance brands

Download FREE Sample Report: Macrocyclic Musks for Cosmetics Market – View in Detailed Research Report


8️⃣ 3. Givaudan

Headquarters: Vernier, Switzerland
Key Offering: Ambrettolide, Muscenone, Macrocyclic Lactone Blends

Givaudan captures 22% of the luxury fragrance musk segment through its proprietary “Molecule Amplification” technology that enhances scent diffusion while using 40% less raw material. The company operates the world’s largest musk R&D facility near Zurich.

Industry Leadership:

  • Launched industry-first biodegradable musk for detergent applications (2023)

  • Strategic partnership with Chanel for bespoke musk development


7️⃣ 4. Symrise AG

Headquarters: Holzminden, Germany
Key Offering: Musk T, Musk MC4, Cosmophenone

Symrise supplies macrocyclic musks to 15 of the top 20 global cosmetic manufacturers, with specialized formulations for pH-sensitive applications. Its Green Chemistry Index tracks 78 sustainability metrics across all musk production lines.

Industry Leadership:

  • Reduced water usage in musk synthesis by 65% since 2019

  • Pioneered cold-process musk technology eliminating high-energy steps


6️⃣ 5. Takasago International Corporation

Headquarters: Tokyo, Japan
Key Offering: Musk-781, Cyclomusk, Florol®

Takasago combines traditional Japanese perfumery with advanced biocatalysis, producing macrocyclic musks with sub-ppm impurity levels. The company holds 240 patents in asymmetric musk synthesis and supplies 45% of Asia’s premium fragrance market.

Industry Leadership:

  • Developed enzyme-engineered musk variants (2023)

  • Strategic alliances with Kao Corporation and Pola Orbis

Download FREE Sample Report: Macrocyclic Musks for Cosmetics Market – View in Detailed Research Report


5️⃣ 6. Soda Aromatic Co., Ltd.

Headquarters: Tokyo, Japan
Key Offering: Galaxolide® replacements, Musk Eco-12

Soda Aromatic specializes in high-purity macrocyclic musks compliant with evolving EU and ASEAN regulations. The company’s Tokyo facility produces over 8,000 tons annually using proprietary closed-loop solvent recovery systems.

Industry Leadership:

  • Developed first REACH-compliant musk for mass market cosmetics

  • 40% production capacity expansion completed in 2024


4️⃣ 7. ACS International

Headquarters: Mumbai, India
Key Offering: Macrocyclic Ketones, Ambretone

ACS leads India’s domestic musk production with formulations tailored for tropical climates. The company’s vertically integrated operations deliver 30% cost savings compared to imported alternatives while meeting international quality standards.

Industry Leadership:

  • First Indian company to achieve EU Cosmos certification for macrocyclic musks

  • Strategic JV with Firmenich for technology transfer (2022)


3️⃣ 8. Conagen

Headquarters: Bedford, Massachusetts, USA
Key Offering: BioMac™ Fermented Musks

Conagen’s innovative fermentation platform produces 100% bio-based macrocyclic musks with identical olfactory profiles to petrochemical-derived versions. The company’s proprietary microbial strains achieve industry-leading 85% conversion rates.

Industry Leadership:

  • First commercial-scale bio-musk facility operational since 2023

  • Partnership with L’Oréal for sustainable fragrance development


2️⃣ 9. Encee Aromatics

Headquarters: Mumbai, India
Key Offering: ECONICLEAN® Series

Encee serves price-sensitive markets with competitively priced macrocyclic musks compliant with ASEAN and Gulf Cooperation Council regulations. The company’s water-based production process eliminates VOC emissions entirely.

Industry Leadership:

  • Supplies 60+ domestic FMCG brands

  • Strategic distribution agreements in 18 African nations


1️⃣ 10. Saraogi Shellac

Headquarters: Kolkata, India
Key Offering: Macro Musk Base, Cyclovert

Saraogi specializes in alkaline-stable musk compounds for haircare and detergent applications, leveraging India’s agricultural byproducts as feedstocks. The company achieves 98.5% process yields through continuous flow chemistry.

Industry Leadership:

  • Patented pH-stable musk technology (2022)

  • Doubling production capacity in 2025

Get Full Report Here: Macrocyclic Musks for Cosmetics Market – View in Detailed Research Report


🌍 Market Outlook: Sustainable Scent Sciences

The macrocyclic musk sector stands at an inflection point as regulatory pressures and consumer preferences drive rapid formulation changes. Bioengineered production methods are projected to capture 45% of the market by 2028, up from just 12% in 2023.

📈 Transformative Industry Trends:

  • Accelerated phase-out of polycyclic musks (68% replacement rate through 2030)

  • EU’s 2026 ban impacting $120 million in traditional musk sales

  • Blockchain-enabled fragrance provenance tracking gaining traction

  • Computational chemistry reducing development cycles by 40%

Get Full Report Here: Macrocyclic Musks for Cosmetics Market – View in Detailed Research Report

The profiled companies represent the vanguard of fragrance innovation, blending cutting-edge science with environmental stewardship to redefine modern perfumery’s olfactory foundations.