Top 10 Companies in the Probiotics Original Powder Industry (2025): Market Leaders Revolutionizing Digestive Wellness

In Business Insights
June 02, 2025

The Global Probiotics Original Powder Market was valued at USD 3,622 Million in 2023 and is projected to reach USD 6,621.16 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 9.00% during the forecast period (2023–2030). This substantial expansion is fueled by rising consumer awareness of gut microbiome health, increasing demand for functional foods, and significant advancements in microbial stabilization technologies.

As scientific research continues to validate the connection between gut health and overall wellbeing, probiotic manufacturers are pioneering innovative formulations that maintain viability while delivering targeted health benefits. This analysis profiles the Top 10 Companies in the Probiotics Original Powder Industry—established leaders and specialized innovators driving the transformation of preventive healthcare through microbial science.


🔟 1. DuPont Nutrition & Biosciences

Headquarters: Wilmington, Delaware, USA
Key Offering: HOWARU® Premium Probiotic Strains

DuPont leads the market with scientifically validated probiotic strains backed by over 100 clinical studies. Their portfolio includes solutions for digestive health, immune support, and specialized applications across food, beverage, and supplement categories.

Innovation Highlights:

  • Proprietary DIRECT-FLEX® technology for enhanced stability
  • GRAS-approved strains with clinically demonstrated benefits
  • Custom formulation services for tailored applications

Download FREE Sample Report: Probiotics Original Powder Market – View in Detailed Research Report


9️⃣ 2. Chr. Hansen Holding A/S

Headquarters: Hørsholm, Denmark
Key Offering: BB-12® and LGG® probiotic strains

With 145+ years in microbial solutions, Chr. Hansen offers one of the industry’s most clinically researched probiotic portfolios, serving customers in over 140 countries with science-backed formulations.

Innovation Highlights:

  • PROBIOTIC+™ shelf-life extension technology
  • Strain-specific health claims supported by 300+ studies
  • Leading position in dairy and infant nutrition applications

8️⃣ 3. Lallemand Health Solutions

Headquarters: Montreal, Canada
Key Offering: Probio’Stick® and Lalflor® series

Lallemand specializes in pharmaceutical-grade probiotic powders with clinically validated benefits, offering B2B solutions for supplements, functional foods, and medical nutrition products.

Innovation Highlights:

  • Patented stabilization technology for oxygen-sensitive strains
  • GMP-certified manufacturing with pharmaceutical standards
  • Strains with EFSA-approved health claims

7️⃣ 4. China-Biotics Inc.

Headquarters: Shanghai, China
Key Offering: Generic probiotic formulations

As Asia’s largest probiotic manufacturer, China-Biotics provides cost-effective solutions for domestic and regional markets, operating one of the continent’s most advanced fermentation facilities.

Innovation Highlights:

  • Annual production capacity exceeding 10,000 metric tons
  • Strategic partnerships with local food and dairy brands
  • Expanding portfolio of specialized probiotic strains

6️⃣ 5. Nestlé Health Science

Headquarters: Vevey, Switzerland
Key Offering: Bifidobacterium lactis HN019

Leveraging Nestlé’s global nutrition expertise, this division develops clinically proven probiotic strains for infant nutrition, medical foods, and consumer health products worldwide.

Innovation Highlights:

  • Pioneering research in maternal-infant microbiome
  • Patented delivery systems for vulnerable populations
  • Global clinical trial network with 50+ studies

Download FREE Sample Report: Probiotics Original Powder Market – View in Detailed Research Report


5️⃣ 6. Danone Nutricia Research

Headquarters: Paris, France
Key Offering: Bifidobacterium lactis (BB-12®)

Danone’s specialized research center drives innovation in probiotic applications for dairy and medical nutrition, with particular expertise in gut-brain axis modulation through microbial interventions.

Innovation Highlights:

  • Industry’s largest probiotic clinical database
  • Groundbreaking research in psychobiotics
  • Vertical integration from strain development to final products

4️⃣ 7. Probi AB

Headquarters: Lund, Sweden
Key Offering: Lactobacillus plantarum 299v

Probi specializes in high-potency, clinically validated probiotic strains for pharmaceutical applications and condition-specific nutritional solutions.

Innovation Highlights:

  • Patented strain-specific delivery technologies
  • Concentrated powder formulations for medical foods
  • Strong IP portfolio with global patents

3️⃣ 8. BioGaia AB

Headquarters: Stockholm, Sweden
Key Offering: L. reuteri Protectis®

A global leader in pediatric probiotics, BioGaia offers products in over 100 countries through pharmaceutical, food, and supplement channels with clinically documented benefits.

Innovation Highlights:

  • Specialized formulations for infants and children
  • Patented gastro-resistant delivery technologies
  • Proven efficacy in 150+ clinical studies

2️⃣ 9. Yakult Honsha Co., Ltd.

Headquarters: Tokyo, Japan
Key Offering: Lactobacillus casei Shirota

Yakult’s proprietary strain represents one of the world’s most extensively researched probiotics, with over 80 years of continuous research and commercialization experience.

Innovation Highlights:

  • Unique fermentation and stabilization processes
  • Comprehensive epidemiological research database
  • Direct-to-consumer probiotic beverage expertise

1️⃣ 10. Novozymes A/S

Headquarters: Bagsværd, Denmark
Key Offering: PrecisionBiotics® range

Novozymes applies industrial biotechnology expertise to probiotic development, with particular strengths in strain selection, enhancement, and large-scale production optimization.

Innovation Highlights:

  • High-throughput screening platform for novel strains
  • Proprietary production scaling technologies
  • Academic partnerships for microbiome research

Get Full Report Here: Probiotics Original Powder Market – View in Detailed Research Report


🌍 Market Outlook: The Next Frontier in Probiotic Science

The probiotics industry is evolving from general wellness products to precision-formulated solutions targeting specific health conditions, supported by advances in microbiome research and stabilization technologies.

📈 Key Market Drivers:

  • Expanding clinical evidence linking gut health to broader wellbeing
  • Innovations in microencapsulation and delivery systems
  • Growing demand across food, beverage, and supplement categories
  • Increasing regulatory clarity in key markets

Get Full Report Here: Probiotics Original Powder Market – View in Detailed Research Report

These industry leaders are not just supplying probiotic ingredients—they’re pioneering a new paradigm in preventive healthcare through microbial science and innovation.