Top 10 Companies in the Hesperidinase Market (2025): Biotech Leaders Driving Next-Gen Enzyme Solutions

In Business Insights
June 01, 2025

The Global Hesperidinase Market was valued at USD 22 million in 2023 and is projected to reach USD 27.96 million by 2032, growing at a Compound Annual Growth Rate (CAGR) of 2.70% during the forecast period (2023-2032). This market growth is fueled by increasing demand for natural bioactive ingredients, expansion in nutraceutical applications, and the rising adoption of enzymatic processes in pharmaceutical and cosmetic formulations.

As industries increasingly shift toward sustainable bio-based solutions, hesperidinase enzymes are playing a pivotal role in enhancing flavonoid bioavailability and functionality. This analysis profiles the Top 10 Companies in the Hesperidinase Market – a carefully selected group of biotechnology innovators and enzyme specialists transforming multiple industries through their expertise.


🔟 1. Ulcho Biochemical

Headquarters: Yancheng, China
Key Offering: High-purity hesperidinase (98-99%)

Ulcho Biochemical has established itself as a market leader in enzyme manufacturing, with particular expertise in flavonoid-modifying enzymes. The company operates advanced microbial fermentation facilities that produce hesperidinase with exceptional purity levels.

Technology Leadership:

  • Proprietary microbial strains for maximum enzyme yield
  • GMP-certified production infrastructure
  • Custom formulation capabilities for specific industry needs

Download FREE Sample Report: Hesperidinase Market – View in Detailed Research Report


9️⃣ 2. Hangzhou Keying Chem

Headquarters: Hangzhou, China
Key Offering: Food and cosmetic-grade enzyme solutions

Hangzhou Keying Chem supplies high-performance hesperidinase formulations to global markets, with a focus on stability-enhanced products for demanding industrial applications.

Technology Leadership:

  • Advanced enzyme stabilization technologies
  • Customizable particle size distributions
  • Stringent quality control protocols

8️⃣ 3. Hangzhou Fanda Chemical

Headquarters: Hangzhou, China
Key Offering: Pharmaceutical-grade hesperidinase

Specializing in enzymes for pharmaceutical use, Hangzhou Fanda Chemical has developed expertise in flavonoid bioconversion processes critical for drug development and formulation.

Technology Leadership:

  • GMP-compliant production batches
  • Crystalline enzyme preparations
  • Proprietary purification methods

7️⃣ 4. Huayuan Shengtai Biological Technology

Headquarters: Xi’an, China
Key Offering: Industrial-scale enzyme production

Huayuan Shengtai focuses on cost-efficient, large-volume manufacturing of hesperidinase for food additive and animal feed applications.

Technology Leadership:

  • High-yield fermentation processes
  • Bulk packaging solutions
  • Application-specific technical support

Download FREE Sample Report: Hesperidinase Market – View in Detailed Research Report


6️⃣ 5. Creative Enzymes

Headquarters: Shirley, New York, USA
Key Offering: Research-grade enzyme preparations

Creative Enzymes provides high-quality hesperidinase to research institutions and biotech companies globally, supporting scientific advancement in enzyme applications.

Technology Leadership:

  • Broad purity range (90%-99.9%)
  • Multiple formulation options
  • Custom enzyme modification services

5️⃣ 6. Novozymes

Headquarters: Bagsværd, Denmark
Key Offering: Industrial enzyme solutions

While not exclusively focused on hesperidinase, Novozymes’ advanced enzyme platform includes specialized flavonoid-modifying enzymes with applications across multiple industries.

Technology Leadership:

  • Proprietary microbial strain development
  • Sustainable production methodologies
  • Enzyme stabilization technologies

4️⃣ 7. Advanced Enzyme Technologies